-
1
-
-
33746353046
-
LKB1-dependent signaling pathways
-
Alessi, D.R., Sakamoto, K. & Bayascas, J.R. (2006) LKB1-dependent signaling pathways. Annu. Rev. Biochem. 75, 137-163.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 137-163
-
-
Alessi, D.R.1
Sakamoto, K.2
Bayascas, J.R.3
-
2
-
-
79953830840
-
AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization
-
Amato, S., Liu, X., Zheng, B., Cantley, L., Rakic, P. & Man, H.Y. (2011) AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization. Science 332, 247-251.
-
(2011)
Science
, vol.332
, pp. 247-251
-
-
Amato, S.1
Liu, X.2
Zheng, B.3
Cantley, L.4
Rakic, P.5
Man, H.Y.6
-
3
-
-
67049100271
-
LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye
-
Amin, N., Khan, A., St Johnston, D., Tomlinson, I., Martin, S., Brenman, J. & McNeill, H. (2009) LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye. Proc. Natl Acad. Sci. USA 106, 8941-8946.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8941-8946
-
-
Amin, N.1
Khan, A.2
St Johnston, D.3
Tomlinson, I.4
Martin, S.5
Brenman, J.6
McNeill, H.7
-
4
-
-
0038614742
-
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD
-
Baas, A.F., Boudeau, J., Sapkota, G.P., Smit, L., Medema, R., Morrice, N.A., Alessi, D.R. & Clevers, H.C. (2003) Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J. 22, 3062-3072.
-
(2003)
EMBO J.
, vol.22
, pp. 3062-3072
-
-
Baas, A.F.1
Boudeau, J.2
Sapkota, G.P.3
Smit, L.4
Medema, R.5
Morrice, N.A.6
Alessi, D.R.7
Clevers, H.C.8
-
5
-
-
1542777034
-
Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD
-
Baas, A.F., Kuipers, J., van der Wel, N.N., Batlle, E., Koerten, H.K., Peters, P.J. & Clevers, H.C. (2004a) Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 116, 457-466.
-
(2004)
Cell
, vol.116
, pp. 457-466
-
-
Baas, A.F.1
Kuipers, J.2
van der Wel, N.N.3
Batlle, E.4
Koerten, H.K.5
Peters, P.J.6
Clevers, H.C.7
-
6
-
-
2942729619
-
LKB1 tumor suppressor protein: PARtaker in cell polarity
-
Baas, A.F., Smit, L. & Clevers, H. (2004b) LKB1 tumor suppressor protein: PARtaker in cell polarity. Trends Cell Biol. 14, 312-319.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 312-319
-
-
Baas, A.F.1
Smit, L.2
Clevers, H.3
-
7
-
-
79952747862
-
Alzheimer's disease
-
Ballard, C., Gauthier, S., Corbett, A., Brayne, C., Aarsland, D. & Jones, E. (2011) Alzheimer's disease. Lancet 377, 1019-1031.
-
(2011)
Lancet
, vol.377
, pp. 1019-1031
-
-
Ballard, C.1
Gauthier, S.2
Corbett, A.3
Brayne, C.4
Aarsland, D.5
Jones, E.6
-
8
-
-
0347596668
-
Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells
-
Benton, R. & St Johnston, D. (2003) Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells. Cell 115, 691-704.
-
(2003)
Cell
, vol.115
, pp. 691-704
-
-
Benton, R.1
St Johnston, D.2
-
9
-
-
0031213571
-
Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity
-
Bohm, H., Brinkmann, V., Drab, M., Henske, A. & Kurzchalia, T.V. (1997) Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity. Curr. Biol. 7, 603-606.
-
(1997)
Curr. Biol.
, vol.7
, pp. 603-606
-
-
Bohm, H.1
Brinkmann, V.2
Drab, M.3
Henske, A.4
Kurzchalia, T.V.5
-
10
-
-
34250844968
-
The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division
-
Bonaccorsi, S., Mottier, V., Giansanti, M.G., Bolkan, B.J., Williams, B., Goldberg, M.L. & Gatti, M. (2007) The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division. Development 134, 2183-2193.
-
(2007)
Development
, vol.134
, pp. 2183-2193
-
-
Bonaccorsi, S.1
Mottier, V.2
Giansanti, M.G.3
Bolkan, B.J.4
Williams, B.5
Goldberg, M.L.6
Gatti, M.7
-
11
-
-
0141753981
-
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
-
Boudeau, J., Baas, A.F., Deak, M., Morrice, N.A., Kieloch, A., Schutkowski, M., Prescott, A.R., Clevers, H.C. & Alessi, D.R. (2003) MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J. 22, 5102-5114.
-
(2003)
EMBO J.
, vol.22
, pp. 5102-5114
-
-
Boudeau, J.1
Baas, A.F.2
Deak, M.3
Morrice, N.A.4
Kieloch, A.5
Schutkowski, M.6
Prescott, A.R.7
Clevers, H.C.8
Alessi, D.R.9
-
12
-
-
10344236460
-
PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos
-
Boyd, L., Guo, S., Levitan, D., Stinchcomb, D.T. & Kemphues, K.J. (1996) PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos. Development 122, 3075-3084.
-
(1996)
Development
, vol.122
, pp. 3075-3084
-
-
Boyd, L.1
Guo, S.2
Levitan, D.3
Stinchcomb, D.T.4
Kemphues, K.J.5
-
13
-
-
37249011204
-
AMPK/LKB1 signaling in epithelial cell polarity and cell division
-
Brenman, J.E. (2007) AMPK/LKB1 signaling in epithelial cell polarity and cell division. Cell Cycle 6, 2755-2759.
-
(2007)
Cell Cycle
, vol.6
, pp. 2755-2759
-
-
Brenman, J.E.1
-
14
-
-
63849210402
-
The regulation and function of mammalian AMPK-related kinases
-
Bright, N.J., Thornton, C. & Carling, D. (2009) The regulation and function of mammalian AMPK-related kinases. Acta Physiol. (Oxf) 196, 15-26.
-
(2009)
Acta Physiol. (Oxf)
, vol.196
, pp. 15-26
-
-
Bright, N.J.1
Thornton, C.2
Carling, D.3
-
15
-
-
54549091120
-
From cells to organs: building polarized tissue
-
Bryant, D.M. & Mostov, K.E. (2008) From cells to organs: building polarized tissue. Nat. Rev. Mol. Cell Biol. 9, 887-901.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 887-901
-
-
Bryant, D.M.1
Mostov, K.E.2
-
16
-
-
57749198014
-
Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes
-
Bultot, L., Horman, S., Neumann, D., Walsh, M.P., Hue, L. & Rider, M.H. (2009) Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes. FEBS Lett. 583, 25-28.
-
(2009)
FEBS Lett.
, vol.583
, pp. 25-28
-
-
Bultot, L.1
Horman, S.2
Neumann, D.3
Walsh, M.P.4
Hue, L.5
Rider, M.H.6
-
17
-
-
0023642627
-
A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis
-
Carling, D., Zammit, V.A. & Hardie, D.G. (1987) A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis. FEBS Lett. 223, 217-222.
-
(1987)
FEBS Lett.
, vol.223
, pp. 217-222
-
-
Carling, D.1
Zammit, V.A.2
Hardie, D.G.3
-
18
-
-
24944547584
-
Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends
-
Dzhindzhev, N.S., Rogers, S.L., Vale, R.D. & Ohkura, H. (2005) Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends. J. Cell Sci. 118, 3781-3790.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3781-3790
-
-
Dzhindzhev, N.S.1
Rogers, S.L.2
Vale, R.D.3
Ohkura, H.4
-
19
-
-
0032731434
-
Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells
-
Ebneth, A., Drewes, G., Mandelkow, E.M. & Mandelkow, E. (1999) Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells. Cell Motil. Cytoskeleton 44, 209-224.
-
(1999)
Cell Motil. Cytoskeleton
, vol.44
, pp. 209-224
-
-
Ebneth, A.1
Drewes, G.2
Mandelkow, E.M.3
Mandelkow, E.4
-
20
-
-
78650308096
-
Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans
-
Gallo, C.M., Wang, J.T., Motegi, F. & Seydoux, G. (2010) Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans. Science 330, 1685-1689.
-
(2010)
Science
, vol.330
, pp. 1685-1689
-
-
Gallo, C.M.1
Wang, J.T.2
Motegi, F.3
Seydoux, G.4
-
21
-
-
35549001736
-
The PAR proteins: fundamental players in animal cell polarization
-
Goldstein, B. & Macara, I.G. (2007) The PAR proteins: fundamental players in animal cell polarization. Dev. Cell 13, 609-622.
-
(2007)
Dev. Cell
, vol.13
, pp. 609-622
-
-
Goldstein, B.1
Macara, I.G.2
-
22
-
-
80052951973
-
Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle
-
Griffin, E.E., Odde, D.J. & Seydoux, G. (2011) Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle. Cell 146, 955-968.
-
(2011)
Cell
, vol.146
, pp. 955-968
-
-
Griffin, E.E.1
Odde, D.J.2
Seydoux, G.3
-
23
-
-
34648828532
-
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
-
Hardie, D.G. (2007) AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat. Rev. Mol. Cell Biol. 8, 774-785.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 774-785
-
-
Hardie, D.G.1
-
24
-
-
80052385397
-
AMP-activated protein kinase: also regulated by ADP?
-
Hardie, D.G., Carling, D. & Gamblin, S.J. (2011) AMP-activated protein kinase: also regulated by ADP? Trends Biochem. Sci. 36, 470-477.
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 470-477
-
-
Hardie, D.G.1
Carling, D.2
Gamblin, S.J.3
-
25
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
-
Hawley, S.A., Boudeau, J., Reid, J.L., Mustard, K.J., Udd, L., Makela, T.P., Alessi, D.R. & Hardie, D.G. (2003) Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J. Biol. 2, 28.
-
(2003)
J. Biol.
, vol.2
, pp. 28
-
-
Hawley, S.A.1
Boudeau, J.2
Reid, J.L.3
Mustard, K.J.4
Udd, L.5
Makela, T.P.6
Alessi, D.R.7
Hardie, D.G.8
-
26
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley, S.A., Pan, D.A., Mustard, K.J., Ross, L., Bain, J., Edelman, A.M., Frenguelli, B.G. & Hardie, D.G. (2005) Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab. 2, 9-19.
-
(2005)
Cell Metab.
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
27
-
-
84861325586
-
PAR-1/MARK: a kinase essential for maintaining the dynamic state of microtubules
-
Hayashi, K., Suzuki, A. & Ohno, S. (2012) PAR-1/MARK: a kinase essential for maintaining the dynamic state of microtubules. Cell Struct. Funct. 37, 21-25.
-
(2012)
Cell Struct. Funct.
, vol.37
, pp. 21-25
-
-
Hayashi, K.1
Suzuki, A.2
Ohno, S.3
-
28
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
-
Hemminki, A., Markie, D., Tomlinson, I., et al. (1998) A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 391, 184-187.
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
-
29
-
-
0031012344
-
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
-
Hemminki, A., Tomlinson, I., Markie, D., Jarvinen, H., Sistonen, P., Bjorkqvist, A.M., Knuutila, S., Salovaara, R., Bodmer, W., Shibata, D., de la Chapelle, A. & Aaltonen, L.A. (1997) Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat. Genet. 15, 87-90.
-
(1997)
Nat. Genet.
, vol.15
, pp. 87-90
-
-
Hemminki, A.1
Tomlinson, I.2
Markie, D.3
Jarvinen, H.4
Sistonen, P.5
Bjorkqvist, A.M.6
Knuutila, S.7
Salovaara, R.8
Bodmer, W.9
Shibata, D.10
de la Chapelle, A.11
Aaltonen, L.A.12
-
30
-
-
39749194712
-
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms
-
Hezel, A.F., Gurumurthy, S., Granot, Z., Swisa, A., Chu, G.C., Bailey, G., Dor, Y., Bardeesy, N. & Depinho, R.A. (2008) Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol. Cell. Biol. 28, 2414-2425.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 2414-2425
-
-
Hezel, A.F.1
Gurumurthy, S.2
Granot, Z.3
Swisa, A.4
Chu, G.C.5
Bailey, G.6
Dor, Y.7
Bardeesy, N.8
Depinho, R.A.9
-
31
-
-
0041305909
-
Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases
-
Hong, S.P., Leiper, F.C., Woods, A., Carling, D. & Carlson, M. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc. Natl Acad. Sci. USA 100, 8839-8843.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 8839-8843
-
-
Hong, S.P.1
Leiper, F.C.2
Woods, A.3
Carling, D.4
Carlson, M.5
-
32
-
-
49649085586
-
AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase
-
Horman, S., Morel, N., Vertommen, D., Hussain, N., Neumann, D., Beauloye, C., El Najjar, N., Forcet, C., Viollet, B., Walsh, M.P., Hue, L. & Rider, M.H. (2008) AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase. J. Biol. Chem. 283, 18505-18512.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 18505-18512
-
-
Horman, S.1
Morel, N.2
Vertommen, D.3
Hussain, N.4
Neumann, D.5
Beauloye, C.6
El Najjar, N.7
Forcet, C.8
Viollet, B.9
Walsh, M.P.10
Hue, L.11
Rider, M.H.12
-
33
-
-
23844471263
-
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases
-
Hurley, R.L., Anderson, K.A., Franzone, J.M., Kemp, B.E., Means, A.R. & Witters, L.A. (2005) The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J. Biol. Chem. 280, 29060-29066.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29060-29066
-
-
Hurley, R.L.1
Anderson, K.A.2
Franzone, J.M.3
Kemp, B.E.4
Means, A.R.5
Witters, L.A.6
-
34
-
-
54549104845
-
Crosstalk between small GTPases and polarity proteins in cell polarization
-
Iden, S. & Collard, J.G. (2008) Crosstalk between small GTPases and polarity proteins in cell polarization. Nat. Rev. Mol. Cell Biol. 9, 846-859.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 846-859
-
-
Iden, S.1
Collard, J.G.2
-
35
-
-
0032487494
-
An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
-
Izumi, Y., Hirose, T., Tamai, Y., Hirai, S., Nagashima, Y., Fujimoto, T., Tabuse, Y., Kemphues, K.J. & Ohno, S. (1998) An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J. Cell Biol. 143, 95-106.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 95-106
-
-
Izumi, Y.1
Hirose, T.2
Tamai, Y.3
Hirai, S.4
Nagashima, Y.5
Fujimoto, T.6
Tabuse, Y.7
Kemphues, K.J.8
Ohno, S.9
-
36
-
-
67650898228
-
LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism
-
Jansen, M., Ten Klooster, J.P., Offerhaus, G.J. & Clevers, H. (2009) LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism. Physiol. Rev. 89, 777-798.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 777-798
-
-
Jansen, M.1
Ten Klooster, J.P.2
Offerhaus, G.J.3
Clevers, H.4
-
37
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
Jenne, D.E., Reimann, H., Nezu, J., Friedel, W., Loff, S., Jeschke, R., Muller, O., Back, W. & Zimmer, M. (1998) Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat. Genet. 18, 38-43.
-
(1998)
Nat. Genet.
, vol.18
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
Muller, O.7
Back, W.8
Zimmer, M.9
-
38
-
-
0034253536
-
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
-
Joberty, G., Petersen, C., Gao, L. & Macara, I.G. (2000) The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat. Cell Biol. 2, 531-539.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 531-539
-
-
Joberty, G.1
Petersen, C.2
Gao, L.3
Macara, I.G.4
-
39
-
-
0034640089
-
PARsing embryonic polarity
-
Kemphues, K. (2000) PARsing embryonic polarity. Cell 101, 345-348.
-
(2000)
Cell
, vol.101
, pp. 345-348
-
-
Kemphues, K.1
-
40
-
-
0024284814
-
Identification of genes required for cytoplasmic localization in early C. elegans embryos
-
Kemphues, K.J., Priess, J.R., Morton, D.G. & Cheng, N.S. (1988) Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52, 311-320.
-
(1988)
Cell
, vol.52
, pp. 311-320
-
-
Kemphues, K.J.1
Priess, J.R.2
Morton, D.G.3
Cheng, N.S.4
-
41
-
-
73649105150
-
C. elegans STRADalpha and SAD cooperatively regulate neuronal polarity and synaptic organization
-
Kim, J.S., Hung, W., Narbonne, P., Roy, R. & Zhen, M. (2010) C. elegans STRADalpha and SAD cooperatively regulate neuronal polarity and synaptic organization. Development 137, 93-102.
-
(2010)
Development
, vol.137
, pp. 93-102
-
-
Kim, J.S.1
Hung, W.2
Narbonne, P.3
Roy, R.4
Zhen, M.5
-
42
-
-
70350366605
-
Kinase-activity-independent functions of atypical protein kinase C in Drosophila
-
Kim, S., Gailite, I., Moussian, B., Luschnig, S., Goette, M., Fricke, K., Honemann-Capito, M., Grubmuller, H. & Wodarz, A. (2009) Kinase-activity-independent functions of atypical protein kinase C in Drosophila. J. Cell Sci. 122, 3759-3771.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3759-3771
-
-
Kim, S.1
Gailite, I.2
Moussian, B.3
Luschnig, S.4
Goette, M.5
Fricke, K.6
Honemann-Capito, M.7
Grubmuller, H.8
Wodarz, A.9
-
43
-
-
77955119964
-
Phosphorylation controls autoinhibition of cytoplasmic linker protein-170
-
Lee, H.S., Komarova, Y.A., Nadezhdina, E.S., Anjum, R., Peloquin, J.G., Schober, J.M., Danciu, O., van Haren, J., Galjart, N., Gygi, S.P., Akhmanova, A. & Borisy, G.G. (2010) Phosphorylation controls autoinhibition of cytoplasmic linker protein-170. Mol. Biol. Cell 21, 2661-2673.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2661-2673
-
-
Lee, H.S.1
Komarova, Y.A.2
Nadezhdina, E.S.3
Anjum, R.4
Peloquin, J.G.5
Schober, J.M.6
Danciu, O.7
van Haren, J.8
Galjart, N.9
Gygi, S.P.10
Akhmanova, A.11
Borisy, G.G.12
-
44
-
-
34250827107
-
Energy-dependent regulation of cell structure by AMP-activated protein kinase
-
Lee, J.H., Koh, H., Kim, M., Kim, Y., Lee, S.Y., Karess, R.E., Lee, S.H., Shong, M., Kim, J.M., Kim, J. & Chung, J. (2007) Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 447, 1017-1020.
-
(2007)
Nature
, vol.447
, pp. 1017-1020
-
-
Lee, J.H.1
Koh, H.2
Kim, M.3
Kim, Y.4
Lee, S.Y.5
Karess, R.E.6
Lee, S.H.7
Shong, M.8
Kim, J.M.9
Kim, J.10
Chung, J.11
-
45
-
-
54549102288
-
Beyond polymer polarity: how the cytoskeleton builds a polarized cell
-
Li, R. & Gundersen, G.G. (2008) Beyond polymer polarity: how the cytoskeleton builds a polarized cell. Nat. Rev. Mol. Cell Biol. 9, 860-873.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 860-873
-
-
Li, R.1
Gundersen, G.G.2
-
46
-
-
12144287284
-
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
-
Lizcano, J.M., Goransson, O., Toth, R., Deak, M., Morrice, N.A., Boudeau, J., Hawley, S.A., Udd, L., Makela, T.P., Hardie, D.G. & Alessi, D.R. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J. 23, 833-843.
-
(2004)
EMBO J.
, vol.23
, pp. 833-843
-
-
Lizcano, J.M.1
Goransson, O.2
Toth, R.3
Deak, M.4
Morrice, N.A.5
Boudeau, J.6
Hawley, S.A.7
Udd, L.8
Makela, T.P.9
Hardie, D.G.10
Alessi, D.R.11
-
47
-
-
0036696011
-
Heads or tails: cell polarity and axis formation in the early Caenorhabditis elegans embryo
-
Lyczak, R., Gomes, J.E. & Bowerman, B. (2002) Heads or tails: cell polarity and axis formation in the early Caenorhabditis elegans embryo. Dev. Cell 3, 157-166.
-
(2002)
Dev. Cell
, vol.3
, pp. 157-166
-
-
Lyczak, R.1
Gomes, J.E.2
Bowerman, B.3
-
48
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning, G., Whyte, D.B., Martinez, R., Hunter, T. & Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
49
-
-
0037461735
-
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
-
Martin, S.G. & St Johnston, D. (2003) A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature 421, 379-384.
-
(2003)
Nature
, vol.421
, pp. 379-384
-
-
Martin, S.G.1
St Johnston, D.2
-
50
-
-
67649983118
-
The tau of MARK: a polarized view of the cytoskeleton
-
Matenia, D. & Mandelkow, E.M. (2009) The tau of MARK: a polarized view of the cytoskeleton. Trends Biochem. Sci. 34, 332-342.
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 332-342
-
-
Matenia, D.1
Mandelkow, E.M.2
-
51
-
-
80052511813
-
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
-
Mihaylova, M.M. & Shaw, R.J. (2011) The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol. 13, 1016-1023.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1016-1023
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
52
-
-
79953233213
-
The LKB1/AMPK polarity pathway
-
Mirouse, V. & Billaud, M. (2011) The LKB1/AMPK polarity pathway. FEBS Lett. 585, 981-985.
-
(2011)
FEBS Lett.
, vol.585
, pp. 981-985
-
-
Mirouse, V.1
Billaud, M.2
-
53
-
-
33748747706
-
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
-
Momcilovic, M., Hong, S.P. & Carlson, M. (2006) Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J. Biol. Chem. 281, 25336-25343.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25336-25343
-
-
Momcilovic, M.1
Hong, S.P.2
Carlson, M.3
-
54
-
-
0026773728
-
par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis
-
Morton, D.G., Roos, J.M. & Kemphues, K.J. (1992) par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis. Genetics 130, 771-790.
-
(1992)
Genetics
, vol.130
, pp. 771-790
-
-
Morton, D.G.1
Roos, J.M.2
Kemphues, K.J.3
-
55
-
-
33748202573
-
Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos
-
Motegi, F. & Sugimoto, A. (2006) Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos. Nat. Cell Biol. 8, 978-985.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 978-985
-
-
Motegi, F.1
Sugimoto, A.2
-
56
-
-
4544316472
-
Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo
-
Munro, E., Nance, J. & Priess, J.R. (2004) Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo. Dev. Cell 7, 413-424.
-
(2004)
Dev. Cell
, vol.7
, pp. 413-424
-
-
Munro, E.1
Nance, J.2
Priess, J.R.3
-
57
-
-
77953121697
-
AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation
-
Nakano, A., Kato, H., Watanabe, T., et al. (2010) AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. Nat. Cell Biol. 12, 583-590.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 583-590
-
-
Nakano, A.1
Kato, H.2
Watanabe, T.3
-
58
-
-
58149339613
-
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
-
Narbonne, P. & Roy, R. (2009) Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457, 210-214.
-
(2009)
Nature
, vol.457
, pp. 210-214
-
-
Narbonne, P.1
Roy, R.2
-
59
-
-
0038583957
-
Yeast Pak1 kinase associates with and activates Snf1
-
Nath, N., McCartney, R.R. & Schmidt, M.C. (2003) Yeast Pak1 kinase associates with and activates Snf1. Mol. Cell. Biol. 23, 3909-3917.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3909-3917
-
-
Nath, N.1
McCartney, R.R.2
Schmidt, M.C.3
-
60
-
-
0037032795
-
Anterior-posterior polarity in C. elegans and Drosophila-PARallels and differences
-
Pellettieri, J. & Seydoux, G. (2002) Anterior-posterior polarity in C. elegans and Drosophila-PARallels and differences. Science 298, 1946-1950.
-
(2002)
Science
, vol.298
, pp. 1946-1950
-
-
Pellettieri, J.1
Seydoux, G.2
-
61
-
-
0033582659
-
CLIP-170 highlights growing microtubule ends in vivo
-
Perez, F., Diamantopoulos, G.S., Stalder, R. & Kreis, T.E. (1999) CLIP-170 highlights growing microtubule ends in vivo. Cell 96, 517-527.
-
(1999)
Cell
, vol.96
, pp. 517-527
-
-
Perez, F.1
Diamantopoulos, G.S.2
Stalder, R.3
Kreis, T.E.4
-
62
-
-
0026793891
-
CLIP-170 links endocytic vesicles to microtubules
-
Pierre, P., Scheel, J., Rickard, J.E. & Kreis, T.E. (1992) CLIP-170 links endocytic vesicles to microtubules. Cell 70, 887-900.
-
(1992)
Cell
, vol.70
, pp. 887-900
-
-
Pierre, P.1
Scheel, J.2
Rickard, J.E.3
Kreis, T.E.4
-
63
-
-
0025293853
-
Identification of a novel nucleotide-sensitive microtubule-binding protein in HeLa cells
-
Rickard, J.E. & Kreis, T.E. (1990) Identification of a novel nucleotide-sensitive microtubule-binding protein in HeLa cells. J. Cell Biol. 110, 1623-1633.
-
(1990)
J. Cell Biol.
, vol.110
, pp. 1623-1633
-
-
Rickard, J.E.1
Kreis, T.E.2
-
64
-
-
84861706622
-
A functional link between localized Oskar, dynamic microtubules, and endocytosis
-
Sanghavi, P., Lu, S. & Gonsalvez, G.B. (2012) A functional link between localized Oskar, dynamic microtubules, and endocytosis. Dev. Biol. 367, 66-77.
-
(2012)
Dev. Biol.
, vol.367
, pp. 66-77
-
-
Sanghavi, P.1
Lu, S.2
Gonsalvez, G.B.3
-
65
-
-
45949103263
-
Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration
-
Sapir, T., Sapoznik, S., Levy, T., Finkelshtein, D., Shmueli, A., Timm, T., Mandelkow, E.M. & Reiner, O. (2008) Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration. J. Neurosci. 28, 5710-5720.
-
(2008)
J. Neurosci.
, vol.28
, pp. 5710-5720
-
-
Sapir, T.1
Sapoznik, S.2
Levy, T.3
Finkelshtein, D.4
Shmueli, A.5
Timm, T.6
Mandelkow, E.M.7
Reiner, O.8
-
66
-
-
0036499467
-
Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome
-
Sapkota, G.P., Boudeau, J., Deak, M., Kieloch, A., Morrice, N. & Alessi, D.R. (2002) Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome. Biochem. J. 362, 481-490.
-
(2002)
Biochem. J.
, vol.362
, pp. 481-490
-
-
Sapkota, G.P.1
Boudeau, J.2
Deak, M.3
Kieloch, A.4
Morrice, N.5
Alessi, D.R.6
-
67
-
-
0346155807
-
Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote
-
Schneider, S.Q. & Bowerman, B. (2003) Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote. Annu. Rev. Genet. 37, 221-249.
-
(2003)
Annu. Rev. Genet.
, vol.37
, pp. 221-249
-
-
Schneider, S.Q.1
Bowerman, B.2
-
68
-
-
0035906940
-
Microtubule "plus-end-tracking proteins": the end is just the beginning
-
Schuyler, S.C. & Pellman, D. (2001) Microtubule "plus-end-tracking proteins": the end is just the beginning. Cell 105, 421-424.
-
(2001)
Cell
, vol.105
, pp. 421-424
-
-
Schuyler, S.C.1
Pellman, D.2
-
69
-
-
80055022978
-
The LKB1 complex-AMPK pathway: the tree that hides the forest
-
Sebbagh, M., Olschwang, S., Santoni, M.J. & Borg, J.P. (2011) The LKB1 complex-AMPK pathway: the tree that hides the forest. Fam. Cancer 10, 415-424.
-
(2011)
Fam. Cancer
, vol.10
, pp. 415-424
-
-
Sebbagh, M.1
Olschwang, S.2
Santoni, M.J.3
Borg, J.P.4
-
70
-
-
67749111502
-
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
-
Shackelford, D.B. & Shaw, R.J. (2009) The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat. Rev. Cancer 9, 563-575.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
71
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw, R.J., Kosmatka, M., Bardeesy, N., Hurley, R.L., Witters, L.A., DePinho, R.A. & Cantley, L.C. (2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl Acad. Sci. USA 101, 3329-3335.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
DePinho, R.A.6
Cantley, L.C.7
-
72
-
-
0041700137
-
Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex
-
Sutherland, C.M., Hawley, S.A., McCartney, R.R., Leech, A., Stark, M.J., Schmidt, M.C. & Hardie, D.G. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr. Biol. 13, 1299-1305.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1299-1305
-
-
Sutherland, C.M.1
Hawley, S.A.2
McCartney, R.R.3
Leech, A.4
Stark, M.J.5
Schmidt, M.C.6
Hardie, D.G.7
-
73
-
-
59149101705
-
MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation
-
Tenlen, J.R., Molk, J.N., London, N., Page, B.D. & Priess, J.R. (2008) MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation. Development 135, 3665-3675.
-
(2008)
Development
, vol.135
, pp. 3665-3675
-
-
Tenlen, J.R.1
Molk, J.N.2
London, N.3
Page, B.D.4
Priess, J.R.5
-
74
-
-
0037015294
-
The fusome and microtubules enrich Par-1 in the oocyte, where it effects polarization in conjunction with Par-3, BicD, Egl, and dynein
-
Vaccari, T. & Ephrussi, A. (2002) The fusome and microtubules enrich Par-1 in the oocyte, where it effects polarization in conjunction with Par-3, BicD, Egl, and dynein. Curr. Biol. 12, 1524-1528.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1524-1528
-
-
Vaccari, T.1
Ephrussi, A.2
-
75
-
-
0034090975
-
The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry
-
Watts, J.L., Morton, D.G., Bestman, J. & Kemphues, K.J. (2000) The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry. Development 127, 1467-1475.
-
(2000)
Development
, vol.127
, pp. 1467-1475
-
-
Watts, J.L.1
Morton, D.G.2
Bestman, J.3
Kemphues, K.J.4
-
76
-
-
23044437445
-
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
Woods, A., Dickerson, K., Heath, R., Hong, S.P., Momcilovic, M., Johnstone, S.R., Carlson, M. & Carling, D. (2005) Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2, 21-33.
-
(2005)
Cell Metab.
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
77
-
-
10744230065
-
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
-
Woods, A., Johnstone, S.R., Dickerson, K., Leiper, F.C., Fryer, L.G., Neumann, D., Schlattner, U., Wallimann, T., Carlson, M. & Carling, D. (2003) LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr. Biol. 13, 2004-2008.
-
(2003)
Curr. Biol.
, vol.13
, pp. 2004-2008
-
-
Woods, A.1
Johnstone, S.R.2
Dickerson, K.3
Leiper, F.C.4
Fryer, L.G.5
Neumann, D.6
Schlattner, U.7
Wallimann, T.8
Carlson, M.9
Carling, D.10
-
78
-
-
33751229931
-
A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
-
Xie, M., Zhang, D., Dyck, J.R., Li, Y., Zhang, H., Morishima, M., Mann, D.L., Taffet, G.E., Baldini, A., Khoury, D.S. & Schneider, M.D. (2006) A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc. Natl Acad. Sci. USA 103, 17378-17383.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17378-17383
-
-
Xie, M.1
Zhang, D.2
Dyck, J.R.3
Li, Y.4
Zhang, H.5
Morishima, M.6
Mann, D.L.7
Taffet, G.E.8
Baldini, A.9
Khoury, D.S.10
Schneider, M.D.11
-
79
-
-
33751204464
-
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
-
Zhang, L., Li, J., Young, L.H. & Caplan, M.J. (2006) AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc. Natl Acad. Sci. USA 103, 17272-17277.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17272-17277
-
-
Zhang, L.1
Li, J.2
Young, L.H.3
Caplan, M.J.4
-
80
-
-
33846521353
-
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
-
Zheng, B. & Cantley, L.C. (2007) Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase. Proc. Natl Acad. Sci. USA 104, 819-822.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 819-822
-
-
Zheng, B.1
Cantley, L.C.2
|