Development of a new microfluidic platform integrating co-cultures of intestinal and liver cell lines

Toxicology in Vitro

Volumn 28, Issue 5, 2014, Pages 885-895

  Bricks, Thibault ^a   Paullier, Patrick ^a   Legendre, Audrey ^a   Fleury, Marie José ^a   Zeller, Perrine ^a   Merlier, Franck ^b   Anton, Pauline M ^c   Leclerc, Eric ^a  

^a UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

^b UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

^c INSTITUT POLYTECHNIQUE LASALLE BEAUVAIS   (France)

Author keywords

Caco 2 TC7; Co cultures; Drug screening; HepG2 C3A; Microfluidic biochips; Phenacetin

Indexed keywords

CYTOCHROME P450 1A; PARACETAMOL; PHENACETIN; POLYCARBONATE; CYTOCHROME P450 1A1;

ARTICLE; BIOCHIP; BIOREACTOR; BIOTRANSFORMATION; CELL CULTURE; CELL LINE; CELL METABOLISM; CELL TRANSPORT; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE CELL; INTESTINE MUCOSA PERMEABILITY; LIVER CELL; MICROFLUIDICS; PETRI DISH; SIMULATION; CACO 2 CELL LINE; HEPG2 CELL LINE; INTESTINE ABSORPTION; LIVER; METABOLISM; PROCEDURES;

ACETAMINOPHEN; BIOREACTORS; CACO-2 CELLS; COCULTURE TECHNIQUES; CYTOCHROME P-450 CYP1A1; HEP G2 CELLS; HUMANS; INTESTINAL ABSORPTION; LIVER; MICROFLUIDICS; PHENACETIN;

EID: 84899535269     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.02.005     Document Type: Article

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