An exploratory study of two Caco-2 cell models for oral absorption: A report on their within-laboratory and between-laboratory variability, and their predictive capacity

Alternatives to Laboratory Animals

Volumn 38, Issue 5, 2010, Pages 367-386

  Prieto, Pilar ^a   Hoffmann, Sebastian ^b   Tirelli, Valentina ^c   Tancredi, Francesco ^c   González, Isabel ^d   Bermejo, Marival ^d   De Angelis, Isabella ^c  

^a JOINT RESEARCH CENTRE   (Italy)

^b Seh Consulting + Services   (Germany)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Caco 2; Caco 2 TC7; Intestinal absorption; Prediction model; Prevalidation

Indexed keywords

ACETYLSALICYLIC ACID; ATENOLOL; CARBON 14; CIMETIDINE; COLCHICINE; COPPER SULFATE; DEOXYGLUCOSE; ETHYLENE GLYCOL; LUCIFER YELLOW; MANNITOL; PARACETAMOL; PARAQUAT; PROPRANOLOL; SODIUM AZIDE; VALPROIC ACID;

ACTIVE TRANSPORT; ANIMAL TESTING ALTERNATIVE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CELL STRAIN CACO 2; CONTROLLED STUDY; ELECTRIC RESISTANCE; EUROPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; LABORATORY; MATHEMATICAL MODEL; PERMEABILITY; PREDICTION; PRIORITY JOURNAL; REPRODUCIBILITY; TOXICITY TESTING;

EID: 79251493055     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119291003800510     Document Type: Article

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