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Volumn 108, Issue 7, 2011, Pages 1704-1715

Improvement of HepG2/C3a cell functions in a microfluidic biochip

Author keywords

Hepatocytes; Liver; Microfluidic biochip; PDMS; Transcriptomic

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELL CULTURE; CELL DEATH; ENZYMES; GENES; LIVER; METABOLISM; MICROCHANNELS; MICROFLUIDICS; PHYSIOLOGY; PULSE WIDTH MODULATION; TISSUE ENGINEERING;

EID: 79953236870     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23104     Document Type: Article
Times cited : (89)

References (44)
  • 1
    • 0037450505 scopus 로고    scopus 로고
    • Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors
    • Akiyama TE, Gonzalez FJ. 2003. Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors. Biochim Biophys Acta 1619: 223-234.
    • (2003) Biochim Biophys Acta , vol.1619 , pp. 223-234
    • Akiyama, T.E.1    Gonzalez, F.J.2
  • 2
    • 77949280164 scopus 로고    scopus 로고
    • Role of human liver microsomes in in vitro metabolism of drugs: A review
    • Asha S, Vidyavathi M. 2010. Role of human liver microsomes in in vitro metabolism of drugs: A review. Appl Biochem Biotechnol 160: 1699-1722.
    • (2010) Appl Biochem Biotechnol , vol.160 , pp. 1699-1722
    • Asha, S.1    Vidyavathi, M.2
  • 3
    • 34147108130 scopus 로고    scopus 로고
    • Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity
    • Baudoin R, Corlu A, Griscom L, Legallais C, Leclerc E. 2007a. Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity. Toxicol In Vitro 21: 535-544.
    • (2007) Toxicol In Vitro , vol.21 , pp. 535-544
    • Baudoin, R.1    Corlu, A.2    Griscom, L.3    Legallais, C.4    Leclerc, E.5
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 64549117445 scopus 로고    scopus 로고
    • Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes
    • Chang T, Hughes-Fulford M. 2009. Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes. Tissue Eng Part A 15: 559-567.
    • (2009) Tissue Eng Part A , vol.15 , pp. 559-567
    • Chang, T.1    Hughes-Fulford, M.2
  • 9
    • 67749115964 scopus 로고    scopus 로고
    • Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
    • Chao P, Maguire T, Novik E, Cheng KC, Yarmush ML. 2009. Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human. Biochem Pharmacol 78: 625-632.
    • (2009) Biochem Pharmacol , vol.78 , pp. 625-632
    • Chao, P.1    Maguire, T.2    Novik, E.3    Cheng, K.C.4    Yarmush, M.L.5
  • 10
    • 0032136806 scopus 로고    scopus 로고
    • Diffusion of gases in silicone polymer: Molecular dynamics simulations
    • Charati S, Stern S. 1998. Diffusion of gases in silicone polymer: Molecular dynamics simulations. Macromolecules 31: 5529-5535.
    • (1998) Macromolecules , vol.31 , pp. 5529-5535
    • Charati, S.1    Stern, S.2
  • 11
    • 0035756796 scopus 로고    scopus 로고
    • Review of a flat membrane bioreactor as a bioartificial liver
    • De Bartolo L, Bader A. 2001. Review of a flat membrane bioreactor as a bioartificial liver. Ann Transplant 6: 40-46.
    • (2001) Ann Transplant , vol.6 , pp. 40-46
    • De Bartolo, L.1    Bader, A.2
  • 12
    • 0036216461 scopus 로고    scopus 로고
    • Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues
    • De Kanter R, Monshouwer M, Meijer D, Groothuis G. 2002. Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues. Curr Drug Metab 3: 39-59.
    • (2002) Curr Drug Metab , vol.3 , pp. 39-59
    • De Kanter, R.1    Monshouwer, M.2    Meijer, D.3    Groothuis, G.4
  • 14
    • 34147102481 scopus 로고    scopus 로고
    • Biotransformation: A balance between bioactivation and detoxification
    • In: Williams PL, James RC, Roberts SM, editors. New York, NY: John Wiley & Sons.
    • Franklin MR, Yost GS. 2000. Biotransformation: A balance between bioactivation and detoxification. In: Williams PL, James RC, Roberts SM, editors. Principles of toxicology: Environmental and industrial applications. New York, NY: John Wiley & Sons, pp. 57-86.
    • (2000) Principles of toxicology: Environmental and industrial applications , pp. 57-86
    • Franklin, M.R.1    Yost, G.S.2
  • 16
    • 18244366662 scopus 로고    scopus 로고
    • Tissue enginnering-Current challenges and expanding opportunities
    • Griffith L, Naughton G. 2002. Tissue enginnering-Current challenges and expanding opportunities. Science 295: 1009-1014.
    • (2002) Science , vol.295 , pp. 1009-1014
    • Griffith, L.1    Naughton, G.2
  • 17
    • 0031832805 scopus 로고    scopus 로고
    • Liver cell models in in vitro toxicology
    • Guillouzo A. 1998. Liver cell models in in vitro toxicology. Environ Health Respect 106: 511-532.
    • (1998) Environ Health Respect , vol.106 , pp. 511-532
    • Guillouzo, A.1
  • 18
    • 68649096405 scopus 로고    scopus 로고
    • New perspectives in the use of human hepatocytes in the preclinical drug development process
    • Guillouzo A. 2008. New perspectives in the use of human hepatocytes in the preclinical drug development process. Ann Pharm Fr 66: 288-295.
    • (2008) Ann Pharm Fr , vol.66 , pp. 288-295
    • Guillouzo, A.1
  • 19
    • 57749188894 scopus 로고    scopus 로고
    • Global gene expression changes including drug metabolism and disposition induced by three-dimensional culture of HepG2 cells-Involvement of microtubules
    • Horiuchi SI, Ishida S, Hongo T, Ishikawa Y, Miyajima A, Sawada J, Ohno Y, Nakazawa K, Ozawa S. 2009. Global gene expression changes including drug metabolism and disposition induced by three-dimensional culture of HepG2 cells-Involvement of microtubules. Biochem Biophys Res Commun 378: 558-562.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 558-562
    • Horiuchi, S.I.1    Ishida, S.2    Hongo, T.3    Ishikawa, Y.4    Miyajima, A.5    Sawada, J.6    Ohno, Y.7    Nakazawa, K.8    Ozawa, S.9
  • 20
    • 0033822059 scopus 로고    scopus 로고
    • A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition
    • Kelly J, Sussman N. 2000. A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition. J Biomol Screen 5: 249-254.
    • (2000) J Biomol Screen , vol.5 , pp. 249-254
    • Kelly, J.1    Sussman, N.2
  • 21
    • 0141690719 scopus 로고    scopus 로고
    • Surface chemistry modulates fibronectin conformation and directs integrin binding and specificity to control cell adhesion
    • Keselowsky BG, Collard DM, Garcia AJ, 2003. Surface chemistry modulates fibronectin conformation and directs integrin binding and specificity to control cell adhesion. J Biomed Mater Res A 66: 247-259.
    • (2003) J Biomed Mater Res A , vol.66 , pp. 247-259
    • Keselowsky, B.G.1    Collard, D.M.2    Garcia, A.J.3
  • 22
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • Knowles BB, Howe CC, Aden DP. 1980. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209: 497-499.
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 23
    • 0041695170 scopus 로고    scopus 로고
    • Cell culture in 3-dimensional microfluidic structure of PDMS (polydimethylsiloxane)
    • Leclerc E, Sakai Y, Fujii T. 2003. Cell culture in 3-dimensional microfluidic structure of PDMS (polydimethylsiloxane). Biomed Microdevices 5: 109-114.
    • (2003) Biomed Microdevices , vol.5 , pp. 109-114
    • Leclerc, E.1    Sakai, Y.2    Fujii, T.3
  • 24
    • 3042614049 scopus 로고    scopus 로고
    • Perfusion culture of fetal human hepatocytes in microfluidic-environments
    • Leclerc E, Sakai Y, Fujii T. 2004. Perfusion culture of fetal human hepatocytes in microfluidic-environments. Biochem Eng J 20: 143-148.
    • (2004) Biochem Eng J , vol.20 , pp. 143-148
    • Leclerc, E.1    Sakai, Y.2    Fujii, T.3
  • 25
    • 0344737989 scopus 로고    scopus 로고
    • Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devices
    • Lee JN, Park C, Whitesides GM. 2003. Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devices. Anal Chem 75: 6544-6554.
    • (2003) Anal Chem , vol.75 , pp. 6544-6554
    • Lee, J.N.1    Park, C.2    Whitesides, G.M.3
  • 27
    • 38949218019 scopus 로고    scopus 로고
    • Cell shape, cell-cell contact, cell-extracellular matrix contact and cell polarity are all required for the maximum induction of CYP2B1 and CYP2B2 gene expression by phenobarbital in adult rat cultured hepatocytes
    • Oda H, Yoshida Y, Kawamura A, Kakinuma A. 2008. Cell shape, cell-cell contact, cell-extracellular matrix contact and cell polarity are all required for the maximum induction of CYP2B1 and CYP2B2 gene expression by phenobarbital in adult rat cultured hepatocytes. Biochem Pharmacol 75: 1209-1217.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1209-1217
    • Oda, H.1    Yoshida, Y.2    Kawamura, A.3    Kakinuma, A.4
  • 28
    • 19544374885 scopus 로고    scopus 로고
    • Microfabricated grooved substrates as platforms for bioartificial liver reactors
    • Park J, Berthiaume F, Toner M, Yarmush ML, Tilles AW. 2005. Microfabricated grooved substrates as platforms for bioartificial liver reactors. Biotechnol Bioeng 90: 632-644.
    • (2005) Biotechnol Bioeng , vol.90 , pp. 632-644
    • Park, J.1    Berthiaume, F.2    Toner, M.3    Yarmush, M.L.4    Tilles, A.W.5
  • 29
    • 77949285974 scopus 로고    scopus 로고
    • System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: Human hepatocytes versus liver microsomes versus recombinant enzymes
    • Parkinson A, Kazmi F, Buckley DB, Yerino P, Ogilvie BW, Paris BL. 2010. System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: Human hepatocytes versus liver microsomes versus recombinant enzymes. Drug Metab Pharmacokinet 25: 16-27.
    • (2010) Drug Metab Pharmacokinet , vol.25 , pp. 16-27
    • Parkinson, A.1    Kazmi, F.2    Buckley, D.B.3    Yerino, P.4    Ogilvie, B.W.5    Paris, B.L.6
  • 30
    • 0031790097 scopus 로고    scopus 로고
    • Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain
    • Parmar D, Dhawan A, Seth PK. 1998. Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain. Mol Cell Biochem 189: 201-205.
    • (1998) Mol Cell Biochem , vol.189 , pp. 201-205
    • Parmar, D.1    Dhawan, A.2    Seth, P.K.3
  • 32
    • 0036019367 scopus 로고    scopus 로고
    • Functional Behavior of Primary Rat Liver Cells in a Three-Dimensional Perfused Microarray Bioreactor
    • Powers MJ, Janigian DM, Wack KE, Baker CS, Stolz DB, Griffith LG. 2002. Functional Behavior of Primary Rat Liver Cells in a Three-Dimensional Perfused Microarray Bioreactor. Tissue Eng 8: 499-513.
    • (2002) Tissue Eng , vol.8 , pp. 499-513
    • Powers, M.J.1    Janigian, D.M.2    Wack, K.E.3    Baker, C.S.4    Stolz, D.B.5    Griffith, L.G.6
  • 34
    • 36448936383 scopus 로고    scopus 로고
    • TGFbeta-SMAD signal transduction: Molecular specificity and functional flexibility
    • Schmierer B, Hill CS. 2007. TGFbeta-SMAD signal transduction: Molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 8: 970-982.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 35
    • 0036200587 scopus 로고    scopus 로고
    • Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression
    • Schrem H, Klempnauer J, Borlak J. 2002. Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression. Pharmacol Rev 54: 129-158.
    • (2002) Pharmacol Rev , vol.54 , pp. 129-158
    • Schrem, H.1    Klempnauer, J.2    Borlak, J.3
  • 37
    • 75749153235 scopus 로고    scopus 로고
    • A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip
    • Sung JH, Kam C, Shuler MJ. 2010. A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip. Lab Chip 10: 446-455.
    • (2010) Lab Chip , vol.10 , pp. 446-455
    • Sung, J.H.1    Kam, C.2    Shuler, M.J.3
  • 38
    • 67650481611 scopus 로고    scopus 로고
    • A microfluidic 3D hepatocyte chip for drug toxicity testing
    • Toh YC, Lim TC, Tai D, Xiao G, van Noort D, Yu H. 2009. A microfluidic 3D hepatocyte chip for drug toxicity testing. Lab Chip 9: 2026-2031.
    • (2009) Lab Chip , vol.9 , pp. 2026-2031
    • Toh, Y.C.1    Lim, T.C.2    Tai, D.3    Xiao, G.4    van Noort, D.5    Yu, H.6
  • 39
    • 1842814047 scopus 로고    scopus 로고
    • Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies
    • Viravaidya K, Shuler ML. 2004. Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies. Biotechnol Prog 20: 590-597.
    • (2004) Biotechnol Prog , vol.20 , pp. 590-597
    • Viravaidya, K.1    Shuler, M.L.2
  • 40
    • 39149134269 scopus 로고    scopus 로고
    • Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor
    • Vrzal R, Daujat-Chavanieu M, Pascussi JM, Ulrichova J, Maurel P, Dvorak Z. 2008. Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor. Eur J Pharmacol 581: 244-254.
    • (2008) Eur J Pharmacol , vol.581 , pp. 244-254
    • Vrzal, R.1    Daujat-Chavanieu, M.2    Pascussi, J.M.3    Ulrichova, J.4    Maurel, P.5    Dvorak, Z.6
  • 42
    • 0029921547 scopus 로고    scopus 로고
    • Molecular genetics of early liver development
    • Zaret KS. 1996. Molecular genetics of early liver development. Annu Rev Physiol 58: 231-251.
    • (1996) Annu Rev Physiol , vol.58 , pp. 231-251
    • Zaret, K.S.1
  • 44
    • 0001208214 scopus 로고    scopus 로고
    • Acetaminophen hepatotoxicity
    • Zimmerman HJ. 1998. Acetaminophen hepatotoxicity. Clin Liver Dis 2: 523-541.
    • (1998) Clin Liver Dis , vol.2 , pp. 523-541
    • Zimmerman, H.J.1


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