Dose-dependent targeted suppression of P-glycoprotein expression and function in Caco-2 cells

Molecular Pharmaceutics

Volumn 10, Issue 6, 2013, Pages 2323-2330

  Lee, Stephen D ^a   Osei Twum, Jo Ann ^a   Wasan, Kishor M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

ATP binding cassette transporters; drug transport; gastrointestinal absorption; multidrug resistance; P glycoprotein; siRNA

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; POLYCARBONATE; RHODAMINE 123; SMALL INTERFERING RNA;

ARTICLE; BRUSH BORDER; CELL STRAIN CACO 2; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUSPENSION; TIGHT JUNCTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CACO-2 CELLS; HUMANS; P-GLYCOPROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84878635355     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300668e     Document Type: Article

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