A self-regulating cell culture analog device to mimic animal and human toxicological responses

Biotechnology and Bioengineering

Volumn 52, Issue 1, 1996, Pages 45-60

  Shuler, M L ^a   Ghanem, A ^a   Quick, D ^a   Wong, M C ^a,b   Miller, P ^a  

^a School of Operations Research and Industrial Engineering   (United States)

^b NONE   (United States)

Author keywords

cell culture analog; In vitro toxicology; physiologically based pharmacokinetic models

Indexed keywords

CHEMICALS; HAZARDOUS MATERIALS; METABOLISM; METABOLITES; NAPHTHALENE; PHARMACOKINETICS; PHYSIOLOGY; TOXICITY;

HUMAN TOXICOLOGICAL RESPONSES; IN VITRO TOXICOLOGY; SELF REGULATING ANALOG DEVICE; TOXIC CHEMICALS;

CELL CULTURE;

GLUTATHIONE; LACTATE DEHYDROGENASE; NAPHTHALENE;

ANIMAL CELL; CELL CULTURE; CELL LINE; CELL POPULATION; COMPARTMENT MODEL; CONFERENCE PAPER; DOSE RESPONSE; ENZYME RELEASE; LD 50; METABOLITE; METHODOLOGY; NONHUMAN; PHYSICAL MODEL; RAT; TOXICOLOGY;

EID: 0030571207     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19961005)52:1<45::AID-BIT5>3.0.CO;2-Z     Document Type: Conference Paper

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