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Volumn 157, Issue 3, 2014, Pages 565-579

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

(25)  Puente, Bao N a   Kimura, Wataru a   Muralidhar, Shalini A a   Moon, Jesung a   Amatruda, James F a   Phelps, Kate L a   Grinsfelder, David a   Rothermel, Beverly A a   Chen, Rui a   Garcia, Joseph A a   Santos, Celio X c   Thet, Suwannee a   Mori, Eiichiro b   Kinter, Michael T d   Rindler, Paul M d   Zacchigna, Serena e   Mukherjee, Shibani b   Chen, David J b   Mahmoud, Ahmed I g   Giacca, Mauro e   more..


Author keywords

[No Author keywords available]

Indexed keywords

DNA; OXYGEN;

EID: 84899533827     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.03.032     Document Type: Article
Times cited : (668)

References (79)
  • 1
    • 0031454026 scopus 로고    scopus 로고
    • Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo
    • R. Agah, L.A. Kirshenbaum, M. Abdellatif, L.D. Truong, S. Chakraborty, L.H. Michael, and M.D. Schneider Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo J. Clin. Invest. 100 1997 2722 2728
    • (1997) J. Clin. Invest. , vol.100 , pp. 2722-2728
    • Agah, R.1    Kirshenbaum, L.A.2    Abdellatif, M.3    Truong, L.D.4    Chakraborty, S.5    Michael, L.H.6    Schneider, M.D.7
  • 2
    • 0016193606 scopus 로고
    • Regeneration of the ventricular myocardium in amphibians
    • R.O. Becker, S. Chapin, and R. Sherry Regeneration of the ventricular myocardium in amphibians Nature 248 1974 145 147
    • (1974) Nature , vol.248 , pp. 145-147
    • Becker, R.O.1    Chapin, S.2    Sherry, R.3
  • 4
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • K. Bersell, S. Arab, B. Haring, and B. Kühn Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury Cell 138 2009 257 270
    • (2009) Cell , vol.138 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3    Kühn, B.4
  • 6
    • 84880040358 scopus 로고    scopus 로고
    • Mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts
    • J. Chen, Z.P. Huang, H.Y. Seok, J. Ding, M. Kataoka, Z. Zhang, X. Hu, G. Wang, Z. Lin, and S. Wang et al. mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts Circ. Res. 112 2013 1557 1566
    • (2013) Circ. Res. , vol.112 , pp. 1557-1566
    • Chen, J.1    Huang, Z.P.2    Seok, H.Y.3    Ding, J.4    Kataoka, M.5    Zhang, Z.6    Hu, X.7    Wang, G.8    Lin, Z.9    Wang, S.10
  • 11
    • 0018991609 scopus 로고
    • Myocardial oxygen and carbohydrate consumption in fetal lambs in utero and in adult sheep
    • D.J. Fisher, M.A. Heymann, and A.M. Rudolph Myocardial oxygen and carbohydrate consumption in fetal lambs in utero and in adult sheep Am. J. Physiol. 238 1980 H399 H405
    • (1980) Am. J. Physiol. , vol.238
    • Fisher, D.J.1    Heymann, M.A.2    Rudolph, A.M.3
  • 12
    • 0036089980 scopus 로고    scopus 로고
    • Cell cycle reentry of ventricular and atrial cardiomyocytes and cells within the epicardium following amputation of the ventricular apex in the axolotl, Amblystoma mexicanum: Confocal microscopic immunofluorescent image analysis of bromodeoxyuridine-labeled nuclei
    • I.L. Flink Cell cycle reentry of ventricular and atrial cardiomyocytes and cells within the epicardium following amputation of the ventricular apex in the axolotl, Amblystoma mexicanum: confocal microscopic immunofluorescent image analysis of bromodeoxyuridine-labeled nuclei Anat. Embryol. (Berl.) 205 2002 235 244
    • (2002) Anat. Embryol. (Berl.) , vol.205 , pp. 235-244
    • Flink, I.L.1
  • 13
    • 0024267688 scopus 로고
    • Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments
    • E.W. Gertz, J.A. Wisneski, W.C. Stanley, and R.A. Neese Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments J. Clin. Invest. 82 1988 2017 2025
    • (1988) J. Clin. Invest. , vol.82 , pp. 2017-2025
    • Gertz, E.W.1    Wisneski, J.A.2    Stanley, W.C.3    Neese, R.A.4
  • 14
    • 79955364546 scopus 로고    scopus 로고
    • Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish
    • J.M. González-Rosa, V. Martín, M. Peralta, M. Torres, and N. Mercader Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish Development 138 2011 1663 1674
    • (2011) Development , vol.138 , pp. 1663-1674
    • González-Rosa, J.M.1    Martín, V.2    Peralta, M.3    Torres, M.4    Mercader, N.5
  • 16
    • 0027244234 scopus 로고
    • Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase
    • R. Heald, M. McLoughlin, and F. McKeon Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase Cell 74 1993 463 474
    • (1993) Cell , vol.74 , pp. 463-474
    • Heald, R.1    McLoughlin, M.2    McKeon, F.3
  • 17
    • 70349859881 scopus 로고    scopus 로고
    • DNA damage, aging, and cancer
    • J.H. Hoeijmakers DNA damage, aging, and cancer N. Engl. J. Med. 361 2009 1475 1485
    • (2009) N. Engl. J. Med. , vol.361 , pp. 1475-1485
    • Hoeijmakers, J.H.1
  • 21
    • 34447526330 scopus 로고    scopus 로고
    • Cardiac mitochondrial bioenergetics, oxidative stress, and aging
    • S. Judge, and C. Leeuwenburgh Cardiac mitochondrial bioenergetics, oxidative stress, and aging Am. J. Physiol. Cell Physiol. 292 2007 C1983 C1992
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Judge, S.1    Leeuwenburgh, C.2
  • 23
    • 0037023632 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts
    • M.A. Laflamme, D. Myerson, J.E. Saffitz, and C.E. Murry Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts Circ. Res. 90 2002 634 640
    • (2002) Circ. Res. , vol.90 , pp. 634-640
    • Laflamme, M.A.1    Myerson, D.2    Saffitz, J.E.3    Murry, C.E.4
  • 24
    • 37349006946 scopus 로고    scopus 로고
    • Prenatal nicotine exposure increases heart susceptibility to ischemia/reperfusion injury in adult offspring
    • J. Lawrence, D. Xiao, Q. Xue, M. Rejali, S. Yang, and L. Zhang Prenatal nicotine exposure increases heart susceptibility to ischemia/reperfusion injury in adult offspring J. Pharmacol. Exp. Ther. 324 2008 331 341
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , pp. 331-341
    • Lawrence, J.1    Xiao, D.2    Xue, Q.3    Rejali, M.4    Yang, S.5    Zhang, L.6
  • 25
    • 22144457305 scopus 로고    scopus 로고
    • A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation
    • N.K. Lee, Y.G. Choi, J.Y. Baik, S.Y. Han, D.W. Jeong, Y.S. Bae, N. Kim, and S.Y. Lee A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation Blood 106 2005 852 859
    • (2005) Blood , vol.106 , pp. 852-859
    • Lee, N.K.1    Choi, Y.G.2    Baik, J.Y.3    Han, S.Y.4    Jeong, D.W.5    Bae, Y.S.6    Kim, N.7    Lee, S.Y.8
  • 26
    • 33750906556 scopus 로고    scopus 로고
    • The redox regulation of PI 3-kinase-dependent signaling
    • N.R. Leslie The redox regulation of PI 3-kinase-dependent signaling Antioxid. Redox Signal. 8 2006 1765 1774
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 1765-1774
    • Leslie, N.R.1
  • 27
    • 0035793914 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of cyclin-dependent kinase 2 increases smaller mononuclear cardiomyocytes
    • H.S. Liao, P.M. Kang, H. Nagashima, N. Yamasaki, A. Usheva, B. Ding, B.H. Lorell, and S. Izumo Cardiac-specific overexpression of cyclin-dependent kinase 2 increases smaller mononuclear cardiomyocytes Circ. Res. 88 2001 443 450
    • (2001) Circ. Res. , vol.88 , pp. 443-450
    • Liao, H.S.1    Kang, P.M.2    Nagashima, H.3    Yamasaki, N.4    Usheva, A.5    Ding, B.6    Lorell, B.H.7    Izumo, S.8
  • 28
    • 77952419621 scopus 로고    scopus 로고
    • Regulation of cardiomyocyte polyploidy and multinucleation by CyclinG1
    • Z. Liu, S. Yue, X. Chen, T. Kubin, and T. Braun Regulation of cardiomyocyte polyploidy and multinucleation by CyclinG1 Circ. Res. 106 2010 1498 1506
    • (2010) Circ. Res. , vol.106 , pp. 1498-1506
    • Liu, Z.1    Yue, S.2    Chen, X.3    Kubin, T.4    Braun, T.5
  • 29
    • 85047677277 scopus 로고
    • Developmental changes in energy substrate use by the heart
    • G.D. Lopaschuk, R.L. Collins-Nakai, and T. Itoi Developmental changes in energy substrate use by the heart Cardiovasc. Res. 26 1992 1172 1180
    • (1992) Cardiovasc. Res. , vol.26 , pp. 1172-1180
    • Lopaschuk, G.D.1    Collins-Nakai, R.L.2    Itoi, T.3
  • 32
    • 0037373455 scopus 로고    scopus 로고
    • Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
    • L.J. Marnett, J.N. Riggins, and J.D. West Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein J. Clin. Invest. 111 2003 583 593
    • (2003) J. Clin. Invest. , vol.111 , pp. 583-593
    • Marnett, L.J.1    Riggins, J.N.2    West, J.D.3
  • 34
  • 36
    • 0026538047 scopus 로고
    • Effects of alcohol on intrauterine oxygen tension in the rat
    • J.A. Mitchell, and B.R. Van Kainen Effects of alcohol on intrauterine oxygen tension in the rat Alcohol. Clin. Exp. Res. 16 1992 308 310
    • (1992) Alcohol. Clin. Exp. Res. , vol.16 , pp. 308-310
    • Mitchell, J.A.1    Van Kainen, B.R.2
  • 37
    • 0034255499 scopus 로고    scopus 로고
    • Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins
    • P.J. Moos, K. Edes, and F.A. Fitzpatrick Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins Proc. Natl. Acad. Sci. USA 97 2000 9215 9220
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9215-9220
    • Moos, P.J.1    Edes, K.2    Fitzpatrick, F.A.3
  • 38
    • 0035351073 scopus 로고    scopus 로고
    • [Generation of new cardiomyocytes in the adult heart: Prospects of myocardial regeneration as an alternative to cardiac transplantation]
    • B. Nadal-Ginard [Generation of new cardiomyocytes in the adult heart: Prospects of myocardial regeneration as an alternative to cardiac transplantation] Rev. Esp. Cardiol. 54 2001 543 550
    • (2001) Rev. Esp. Cardiol. , vol.54 , pp. 543-550
    • Nadal-Ginard, B.1
  • 39
    • 0015993323 scopus 로고
    • Response of the adult newt ventricle to injury
    • J.O. Oberpriller, and J.C. Oberpriller Response of the adult newt ventricle to injury J. Exp. Zool. 187 1974 249 253
    • (1974) J. Exp. Zool. , vol.187 , pp. 249-253
    • Oberpriller, J.O.1    Oberpriller, J.C.2
  • 40
    • 70349446465 scopus 로고    scopus 로고
    • Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
    • E. Owusu-Ansah, and U. Banerjee Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation Nature 461 2009 537 541
    • (2009) Nature , vol.461 , pp. 537-541
    • Owusu-Ansah, E.1    Banerjee, U.2
  • 41
    • 0026616796 scopus 로고
    • Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
    • L.L. Parker, and H. Piwnica-Worms Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase Science 257 1992 1955 1957
    • (1992) Science , vol.257 , pp. 1955-1957
    • Parker, L.L.1    Piwnica-Worms, H.2
  • 42
    • 84881040569 scopus 로고    scopus 로고
    • Inhibition of reactive oxygen species generation attenuates TLR4-mediated proinflammatory and proliferative phenotype of vascular smooth muscle cells
    • Y. Pi, L.L. Zhang, B.H. Li, L. Guo, X.J. Cao, C.Y. Gao, and J.C. Li Inhibition of reactive oxygen species generation attenuates TLR4-mediated proinflammatory and proliferative phenotype of vascular smooth muscle cells Lab. Invest. 93 2013 880 887
    • (2013) Lab. Invest. , vol.93 , pp. 880-887
    • Pi, Y.1    Zhang, L.L.2    Li, B.H.3    Guo, L.4    Cao, X.J.5    Gao, C.Y.6    Li, J.C.7
  • 46
    • 0037073890 scopus 로고    scopus 로고
    • Heart regeneration in zebrafish
    • K.D. Poss, L.G. Wilson, and M.T. Keating Heart regeneration in zebrafish Science 298 2002 2188 2190
    • (2002) Science , vol.298 , pp. 2188-2190
    • Poss, K.D.1    Wilson, L.G.2    Keating, M.T.3
  • 47
    • 0038446797 scopus 로고    scopus 로고
    • A dual role of the GTPase Rac in cardiac differentiation of stem cells
    • M. Pucéat, P. Travo, M.T. Quinn, and P. Fort A dual role of the GTPase Rac in cardiac differentiation of stem cells Mol. Biol. Cell 14 2003 2781 2792
    • (2003) Mol. Biol. Cell , vol.14 , pp. 2781-2792
    • Pucéat, M.1    Travo, P.2    Quinn, M.T.3    Fort, P.4
  • 49
    • 0035313825 scopus 로고    scopus 로고
    • Acclimation to hypoxia increases survival time of zebrafish, Danio rerio, during lethal hypoxia
    • B.B. Rees, F.A. Sudradjat, and J.W. Love Acclimation to hypoxia increases survival time of zebrafish, Danio rerio, during lethal hypoxia J. Exp. Zool. 289 2001 266 272
    • (2001) J. Exp. Zool. , vol.289 , pp. 266-272
    • Rees, B.B.1    Sudradjat, F.A.2    Love, J.W.3
  • 51
    • 0029869829 scopus 로고    scopus 로고
    • Ethanol increases uterine blood flow and fetal arterial blood oxygen tension in the near-term pregnant ewe
    • J.D. Reynolds, D.H. Penning, F. Dexter, B. Atkins, J. Hrdy, D. Poduska, and J.F. Brien Ethanol increases uterine blood flow and fetal arterial blood oxygen tension in the near-term pregnant ewe Alcohol 13 1996 251 256
    • (1996) Alcohol , vol.13 , pp. 251-256
    • Reynolds, J.D.1    Penning, D.H.2    Dexter, F.3    Atkins, B.4    Hrdy, J.5    Poduska, D.6    Brien, J.F.7
  • 52
    • 33745616788 scopus 로고    scopus 로고
    • Hypoxia induces a complex response of globin expression in zebrafish (Danio rerio)
    • A. Roesner, T. Hankeln, and T. Burmester Hypoxia induces a complex response of globin expression in zebrafish (Danio rerio) J. Exp. Biol. 209 2006 2129 2137
    • (2006) J. Exp. Biol. , vol.209 , pp. 2129-2137
    • Roesner, A.1    Hankeln, T.2    Burmester, T.3
  • 53
    • 0000680577 scopus 로고
    • Fetal and neonatal circulation and respiration
    • A.M. Rudolph, and M.A. Heyman Fetal and neonatal circulation and respiration Annu. Rev. Physiol. 36 1974 187 207
    • (1974) Annu. Rev. Physiol. , vol.36 , pp. 187-207
    • Rudolph, A.M.1    Heyman, M.A.2
  • 55
    • 0034617467 scopus 로고    scopus 로고
    • Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells
    • H. Sauer, G. Rahimi, J. Hescheler, and M. Wartenberg Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells FEBS Lett. 476 2000 218 223
    • (2000) FEBS Lett. , vol.476 , pp. 218-223
    • Sauer, H.1    Rahimi, G.2    Hescheler, J.3    Wartenberg, M.4
  • 56
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
    • F.Q. Schafer, and G.R. Buettner Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple Free Radic. Biol. Med. 30 2001 1191 1212
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 58
    • 80052586181 scopus 로고    scopus 로고
    • Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes
    • P. Sdek, P. Zhao, Y. Wang, C.J. Huang, C.Y. Ko, P.C. Butler, J.N. Weiss, and W.R. Maclellan Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes J. Cell Biol. 194 2011 407 423
    • (2011) J. Cell Biol. , vol.194 , pp. 407-423
    • Sdek, P.1    Zhao, P.2    Wang, Y.3    Huang, C.J.4    Ko, C.Y.5    Butler, P.C.6    Weiss, J.N.7    Maclellan, W.R.8
  • 59
    • 35148888161 scopus 로고    scopus 로고
    • Life with oxygen
    • G.L. Semenza Life with oxygen Science 318 2007 62 64
    • (2007) Science , vol.318 , pp. 62-64
    • Semenza, G.L.1
  • 60
    • 84860914325 scopus 로고    scopus 로고
    • Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1
    • L. Siggens, N. Figg, M. Bennett, and R. Foo Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1 FASEB J. 26 2012 2117 2124
    • (2012) FASEB J. , vol.26 , pp. 2117-2124
    • Siggens, L.1    Figg, N.2    Bennett, M.3    Foo, R.4
  • 61
  • 62
    • 0028973482 scopus 로고
    • Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
    • M. Sundaresan, Z.X. Yu, V.J. Ferrans, K. Irani, and T. Finkel Requirement for generation of H2O2 for platelet-derived growth factor signal transduction Science 270 1995 296 299
    • (1995) Science , vol.270 , pp. 296-299
    • Sundaresan, M.1    Yu, Z.X.2    Ferrans, V.J.3    Irani, K.4    Finkel, T.5
  • 65
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • D. Trachootham, J. Alexandre, and P. Huang Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug Discov. 8 2009 579 591
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 66
    • 33751411413 scopus 로고    scopus 로고
    • Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures
    • M. Tsatmali, E.C. Walcott, H. Makarenkova, and K.L. Crossin Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures Mol. Cell. Neurosci. 33 2006 345 357
    • (2006) Mol. Cell. Neurosci. , vol.33 , pp. 345-357
    • Tsatmali, M.1    Walcott, E.C.2    Makarenkova, H.3    Crossin, K.L.4
  • 67
    • 0030969868 scopus 로고    scopus 로고
    • Superoxide production by the mitochondrial respiratory chain
    • J.F. Turrens Superoxide production by the mitochondrial respiratory chain Biosci. Rep. 17 1997 3 8
    • (1997) Biosci. Rep. , vol.17 , pp. 3-8
    • Turrens, J.F.1
  • 68
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • J.F. Turrens Mitochondrial formation of reactive oxygen species J. Physiol. 552 2003 335 344
    • (2003) J. Physiol. , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 73
    • 77952291931 scopus 로고    scopus 로고
    • Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells
    • M. Yoneyama, K. Kawada, Y. Gotoh, T. Shiba, and K. Ogita Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells Neurochem. Int. 56 2010 740 746
    • (2010) Neurochem. Int. , vol.56 , pp. 740-746
    • Yoneyama, M.1    Kawada, K.2    Gotoh, Y.3    Shiba, T.4    Ogita, K.5
  • 74
    • 17644394600 scopus 로고    scopus 로고
    • Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence
    • H. Zhao, J. Joseph, H.M. Fales, E.A. Sokoloski, R.L. Levine, J. Vasquez-Vivar, and B. Kalyanaraman Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence Proc. Natl. Acad. Sci. USA 102 2005 5727 5732
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5727-5732
    • Zhao, H.1    Joseph, J.2    Fales, H.M.3    Sokoloski, E.A.4    Levine, R.L.5    Vasquez-Vivar, J.6    Kalyanaraman, B.7
  • 77
    • 52049110957 scopus 로고    scopus 로고
    • Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products
    • F.R. Laurindo, D.C. Fernandes, and C.X. Santos Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products Methods Enzymol. 441 2008 237 260
    • (2008) Methods Enzymol. , vol.441 , pp. 237-260
    • Laurindo, F.R.1    Fernandes, D.C.2    Santos, C.X.3
  • 79
    • 0041326831 scopus 로고    scopus 로고
    • Effects of age and caloric restriction on glutathione redox state in mice
    • I. Rebrin, S. Kamzalov, and R.S. Sohal Effects of age and caloric restriction on glutathione redox state in mice Free Radic. Biol. Med. 35 2003 626 635
    • (2003) Free Radic. Biol. Med. , vol.35 , pp. 626-635
    • Rebrin, I.1    Kamzalov, S.2    Sohal, R.S.3


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