Mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts

Circulation Research

Volumn 112, Issue 12, 2013, Pages 1557-1566

  Chen, Jinghai ^a   Huang, Zhan Peng ^a   Seok, Hee Young ^a   Ding, Jian ^a   Kataoka, Masaharu ^a   Zhang, Zheng ^a,c   Hu, Xiaoyun ^a   Wang, Gang ^a   Lin, Zhiqiang ^a   Wang, Si ^a   Pu, Willam T ^a,d   Liao, Ronglih ^b,d   Wang, Da Zhi ^a,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c CHONGQING MEDICAL UNIVERSITY   (China)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

cardiomyocyte proliferation; cell cycle; heart disease; miR 17 92; myocardial infarction; PTEN

Indexed keywords

DOXORUBICIN; MICRORNA; MICRORNA 19; MIRNA 17 92; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TENSIN; UNCLASSIFIED DRUG;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; DNA SYNTHESIS; ECHOCARDIOGRAPHY; EMBRYO DEVELOPMENT; GENE OVEREXPRESSION; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MOUSE; NICK END LABELING; NONHUMAN; ONCOGENE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL;

CARDIOMYOCYTE PROLIFERATION; CELL CYCLE; HEART DISEASE; MIR-17-92; MYOCARDIAL INFARCTION; PTEN;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICRORNAS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PTEN PHOSPHOHYDROLASE; RATS; RNA INTERFERENCE; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84880040358     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.300658     Document Type: Article

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