Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

Nature Immunology

Volumn 15, Issue 5, 2014, Pages 473-481

  Mahmud, Shawn A ^a   Manlove, Luke S ^a   Schmitz, Heather M ^a   Xing, Yan ^a   Wang, Yanyan ^b   Owen, David L ^a   Schenkel, Jason M ^c   Boomer, Jonathan S ^d   Green, Jonathan M ^d   Yagita, Hideo ^e   Chi, Hongbo ^b   Hogquist, Kristin A ^a   Farrar, Michael A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; OX40 LIGAND; STAT5 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ADULT; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL MATURATION; CELL POPULATION; CHROMOSOME 1; CHROMOSOME 4; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOSTIMULATION; INTERNAL RIBOSOME ENTRY SITE; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; THYMOCYTE; WILD TYPE;

ANIMALS; ANTIGENS, CD28; CELL DIFFERENTIATION; CELLS, CULTURED; GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN; MAP KINASE KINASE KINASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTOR CROSS-TALK; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, OX40; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 84899475568     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2849     Document Type: Article

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