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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 9, 2014, Pages 2098-2104

Molecular Dynamics simulations of Inhibitor of Apoptosis Proteins and identification of potential small molecule inhibitors

(2) Jayakumar, Jayanthi a Anishetty, Sharmila a

a ANNA UNIVERSITY (India)

Author keywords

Cancer; Inhibitor of Apoptosis Proteins (IAPs); MD simulations; SMAC; Small molecule inhibitors

Indexed keywords

CEMADOTIN; DOLASTATIN 15; LIVIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS; BIRC5 PROTEIN, HUMAN; BIRC7 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; MOLECULAR LIBRARY; OLIGOPEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR PROTEIN; ANTINEOPLASTIC AGENT; MITOCHONDRIAL PROTEIN; N,N DIMETHYLVALYLVALYL N METHYLVALYLPROLYL N BENZYL PROLINAMIDE; SMALL MOLECULE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; MOLECULAR DYNAMICS; SCREENING; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; MOLECULAR LIBRARY; PHARMACOLOGY; ANTINEOPLASTIC ACTIVITY; BINDING AFFINITY; CANCER CELL; DRUG DESIGN; DRUG TARGETING; LIGAND BINDING; MOLECULAR DOCKING; NEOPLASM; PROTEIN EXPRESSION;

INTRACISTERNAL A-PARTICLES;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; OLIGOPEPTIDES; SMALL MOLECULE LIBRARIES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84899104493 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.03.046 Document Type: Article

Times cited : (10)

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