Nature and nurture- genes and environment- predict onset and progression of macular degeneration

Progress in Retinal and Eye Research

Volumn 40, Issue , 2014, Pages 1-15

  Sobrin, Lucia ^a   Seddon, Johanna M ^b,c,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TUFTS UNIVERSITY   (United States)

Author keywords

Age related macular degeneration; Epidemiology; Genetics; Risk factors

Indexed keywords

ANTIOXIDANT; APOLIPOPROTEIN; ARMS 2 PROTEIN; BETA CAROTENE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; COLLAGEN TYPE 10; COMPLEMENT COMPONENT C2; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; HTRA 1 PROTEIN; INTERLEUKIN 1BETA; LOW DENSITY LIPOPROTEIN; MANGANESE; MEMBRANE ANTIGEN; MINERAL; OMEGA 3 FATTY ACID; PLATELET DERIVED GROWTH FACTOR; SELENIUM; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VITAMIN; VITAMIN D; ZEAXANTHIN;

ABDOMINAL OBESITY; ALLELE; ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; AREA UNDER THE CURVE; ATHEROSCLEROSIS; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAROTID ARTERY BIFURCATION; CASE CONTROL STUDY; CELL DEATH; CHOLESTEROL INTAKE; CHROMOSOME; CHRONIC KIDNEY DISEASE; CODING; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; CONTROLLED CLINICAL TRIAL (TOPIC); CROSS-SECTIONAL STUDY; DIETARY INTAKE; DISEASE COURSE; DIZYGOTIC TWINS; DNA METHYLATION; DNA REPAIR; DRUSEN; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EPIGENETICS; EVOLUTION; EXON; EXTRACELLULAR MATRIX; FAT INTAKE; FOLLOW UP; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENETICS; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; GEOGRAPHIC ATROPHY; HEMOLYTIC UREMIC SYNDROME; HEREDITY; HERITABILITY; HUMAN; INCIDENCE; INFLAMMATION; KIDNEY FUNCTION; LIGHT EXPOSURE; LINKAGE ANALYSIS; LIPID BLOOD LEVEL; LIPID PEROXIDATION; META ANALYSIS (TOPIC); MISSENSE MUTATION; MONOZYGOTIC TWINS; NATURAL SCIENCE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OBESITY; OXIDATIVE STRESS; PATHOGENESIS; PATHOPHYSIOLOGY; PENETRANCE; PHENOTYPE; PHOTORECEPTOR; PHYSICAL ACTIVITY; PIGMENT EPITHELIUM; PREVALENCE; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROSPECTIVE STUDY; QUESTIONNAIRE; RECEIVER OPERATING CHARACTERISTIC; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; SMOKING; SMOKING CESSATION; SUBRETINAL NEOVASCULARIZATION; TWINS; VISUAL ACUITY; VITAMIN BLOOD LEVEL; WAIST CIRCUMFERENCE; LIFESTYLE; MACULAR DEGENERATION; ONSET AGE;

AGE OF ONSET; DISEASE PROGRESSION; DNA METHYLATION; GENE-ENVIRONMENT INTERACTION; HUMANS; LIFE STYLE; MACULAR DEGENERATION; PREVALENCE; RISK FACTORS;

EID: 84899081985     PISSN: 13509462     EISSN: 18731635     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2013.12.004     Document Type: Review

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