Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: Epigenetic implications

Ophthalmology

Volumn 118, Issue 7, 2011, Pages 1386-1394

  Seddon, Johanna M ^a,b   Reynolds, Robyn ^a   Shah, Heeral R ^b   Rosner, Bernard ^c  

^a NEW ENGLAND EYE CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHANNING LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETAINE; METHIONINE; OMEGA 3 FATTY ACID; VITAMIN D;

ARTICLE; BEHAVIOR; CIGARETTE SMOKING; CLINICAL ARTICLE; DIETARY INTAKE; DRUSEN; ENVIRONMENTAL FACTOR; EPIGENETICS; EYE PHOTOGRAPHY; GENOTYPE; GEOGRAPHIC ATROPHY; HUMAN; MALE; MONOZYGOTIC TWINS; PHENOTYPE; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION; TWIN DISCORDANCE;

BEHAVIOR; BETAINE; DIET; DISEASE PROGRESSION; EPIGENOMICS; HUMANS; MACULAR DEGENERATION; MALE; METHIONINE; NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PHENOTYPE; RETINAL DRUSEN; SEVERITY OF ILLNESS INDEX; SMOKING; TWINS, MONOZYGOTIC; VITAMIN D;

EID: 79959966019     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2010.12.020     Document Type: Article

References (52)

1. J.M. Seddon, J. Cote, and W.F. Page The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences Arch Ophthalmol 123 2005 321 327 (Pubitemid 41007575)
2. J. Seddon, S. George, and B. Rosner Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US twin study of age-related macular degeneration Arch Ophthalmol 124 2006 995 1001 (Pubitemid 44036322)
3. J.M. Seddon, U.A. Ajani, and B.D. Mitchell Familial aggregation of age-related maculopathy Am J Ophthalmol 123 1997 199 206 (Pubitemid 27066775)
4. C.C. Klaver, R.C. Wolfs, and J.J. Assink Genetic risk of age-related maculopathy: population-based familial aggregation study Arch Ophthalmol 116 1998 1646 1651 (Pubitemid 29001964)
5. S.C. Tomany, J.J. Wang, and R. Van Leeuwen Risk factors for incident age-related macular degeneration: pooled findings from 3 continents Ophthalmology 111 2004 1280 1287 (Pubitemid 38844822)
6. J.M. Seddon, S. George, B. Rosner, and M.L. Klein CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration Hum Hered 61 2006 157 165 (Pubitemid 44385444)
7. P.J. Francis, S. George, and D.W. Schultz The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration Hum Hered 63 2007 212 218 (Pubitemid 46457590)
8. Age-Related Eye Disease Study Group Risk factors associated with age-related macular degeneration: a case control study in the Age-Related Eye Disease Study Age-Related Eye Disease Study Report number 3 Ophthalmology 107 2000 2224 2232
9. J.M. Seddon, J. Cote, and B. Rosner Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake Arch Ophthalmol 121 2003 1728 1737 (Pubitemid 37517440)
10. J.M. Seddon, J. Cote, N. Davis, and B. Rosner Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio Arch Ophthalmol 121 2003 785 792 (Pubitemid 36676214)
11. J.M. Seddon, R. Reynolds, and J. Maller Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables Invest Ophthalmol Vis Sci 50 2009 2044 2053
12. J.M. Seddon, W.C. Willett, F.E. Speizer, and S.E. Hankinson A prospective study of cigarette smoking and age-related macular degeneration in women JAMA 276 1996 1141 1146 (Pubitemid 26329740)
13. N. Parekh, R.J. Chappell, and A.E. Millen Association between vitamin D and age-related macular degeneration in the third National Health and Nutrition Examination Survey, 1988 through 1994 Arch Ophthalmol 125 2007 661 669 (Pubitemid 46762728)
14. J. Maller, S. George, and S. Purcell Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration Nat Genet 38 2006 1055 1059 (Pubitemid 44325932)
15. G.S. Hageman, D.H. Anderson, and L.V. Johnson A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc Natl Acad Sci U S A 102 2005 7227 7232 (Pubitemid 40696361)
16. R.J. Klein, C. Zeiss, and E.Y. Chew Complement factor H polymorphism in age-related macular degeneration Science 308 2005 385 389 (Pubitemid 40530070)
17. A.O. Edwards, R. Ritter III, and K.J. Abel Complement factor H polymorphism and age-related macular degeneration Science 308 2005 421 424 (Pubitemid 40530082)
18. M. Li, P. Atmaca-Sonmez, and M. Othman CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration Nat Genet 38 2006 1049 1054 (Pubitemid 44325931)
19. J.L. Haines, M.A. Hauser, and S. Schmidt Complement factor H variant increases the risk of age-related macular degeneration Science 308 2005 419 421 (Pubitemid 40530081)
20. B. Gold, J.E. Merriam, and J. Zernant Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration Nat Genet 38 2006 458 462
21. J.B. Maller, J.A. Fagerness, and R.C. Reynolds Variation in complement factor 3 is associated with risk of age-related macular degeneration Nat Genet 39 2007 1200 1201 (Pubitemid 47482689)
22. J.R. Yates, T. Sepp, B.K. Matharu Genetic Factors in AMD Study Group Complement C3 variant and the risk of age-related macular degeneration N Engl J Med 357 2007 553 561 (Pubitemid 47236280)
23. J.A. Fagerness, J.B. Maller, and B.M. Neale Variation near complement factor I is associated with risk of advanced AMD Eur J Hum Genet 17 2009 100 104
24. J.M. Seddon, B. Rosner, and R.D. Sperduto Dietary fat and risk for advanced age-related macular degeneration Arch Ophthalmol 119 2001 1191 1199 (Pubitemid 32730008)
25. Age-Related Eye Disease Study Research Group The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS report no. 20 Arch Ophthalmol 125 2007 671 679
26. A.H. Wong, I.I. Gottesman, and A. Petronis Phenotypic differences in genetically identical organisms: the epigenetic perspective Hum Mol Gen 14 suppl 2005 R11 R18
27. P. Poulsen, M. Esteller, A. Vaag, and M.F. Fraga The epigenetic basis of twin discordance in age-related diseases Pediatr Res 61 2007 38R42
28. M.F. Fraga, E. Ballestar, and M.F. Paz Epigenetic differences arise during the lifetime of monozygotic twins Proc Natl Acad Sci U S A 102 2005 10604 10609 (Pubitemid 41061601)
29. S.H. Zeisel Epigenetic mechanisms for nutrition determinants of later health outcomes Am J Clin Nutr 89 2009 1488S93
30. S. Jablon, J.V. Neel, H. Gershowitz, and G.F. Atkinson The NAS-NRC twin panel: methods of construction of the panel, zygosity diagnosis, and proposed use Am J Hum Genet 19 1967 133 161
31. J.M. Seddon, S. Sharma, and R.A. Adelman Evaluation of the clinical age-related maculopathy staging system Ophthalmology 113 2006 260 266 (Pubitemid 43170775)
32. R. Cederlof, L. Friberg, E. Jonsson, and L. Kaij Studies on similarity diagnosis in twins with the aid of mailed questionnaires Acta Genet Stat Med 11 1961 338 362
33. Z. Hrubec, and C.D. Robinette The study of human twins in medical research N Engl J Med 310 1984 435 441 (Pubitemid 14186360)
34. J. Jakobsdottir, Y.P. Conley, and D.E. Weeks Susceptibility genes for age-related maculopathy on chromosome 10q26 Am J Hum Gen 77 2005 389 407 (Pubitemid 41192646)
35. A. Dewan, M. Liu, and S. Hartman HTRA1 promoter polymorphism in wet age-related macular degeneration Science 314 2006 989 992 (Pubitemid 44749943)
36. Z. Yang, N.J. Camp, and H. Sun A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration Science 314 2006 992 993 (Pubitemid 44749944)
37. A. Kanda, W. Chen, and M. Othman A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration Proc Natl Acad Sci U S A 104 2007 16227 16232 (Pubitemid 350099389)
38. B.M. Neale, J. Fagerness, and R. Reynolds Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC) Proc Natl Acad Sci U S A 107 2010 7395 7400
39. R. Klein, M.D. Davis, and Y.L. Magli The Wisconsin Age-Related Maculopathy Grading System Ophthalmology 98 1991 1128 1134
40. U.A. Ajani, W.C. Willett, J.M. Seddon Eye Disease Case-Control Study Group Reproducibility of a food frequency questionnaire for use in ocular research Invest Ophthalmol Vis Sci 35 1994 2725 2733 (Pubitemid 24149783)
41. J.M. Seddon, P.J. Francis, and S. George Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration JAMA 297 2007 1793 1800 (Pubitemid 46658648)
42. R.K. Shuler Jr, S. Schmidt, and P. Gallins Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration Ophthalmology 115 2008 520 524
43. J.M. Seddon, R. Reynolds, and B. Rosner Peripheral retinal drusen and reticular pigment: association with CFHY402H and CFHrs1410996 genotypes in family and twin studies Invest Ophthalmol Vis Sci 50 2009 586 591
44. S.S. Schleithoff, A. Zittermann, and G. Tenderich Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial Am J Clin Nutr 83 2006 754 759 (Pubitemid 44713136)
45. J.M. Seddon, G. Gensler, M.L. Klein, and R.C. Milton Evaluation of plasma homocysteine and risk of age-related macular degeneration Am J Ophthalmol 141 2006 201 203 (Pubitemid 43016200)
46. A.K. Vine, J. Stader, and K. Branham Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration Ophthalmology 112 2005 2076 2080 (Pubitemid 41720983)
47. S.E. Chiuve, E.L. Giovannucci, and S.E. Hankinson The association between betaine and choline intakes and the plasma concentrations of homocysteine in women Am J Clin Nutr 86 2007 1073 1081 (Pubitemid 47538311)
48. S.A. Craig Betaine in human nutrition Am J Clin Nutr 80 2004 539 549 (Pubitemid 41115516)
49. L.B. Bailey Folate, methyl-related nutrients, alcohol, and the MTHFR 677C->T polymorphism affect cancer risk: intake recommendations J Nutr 133 suppl 2003 3748S53
50. C.J. Hammond, A.R. Webster, and H. Snieder Genetic influence on early age-related maculopathy: a twin study Ophthalmology 109 2002 730 736 (Pubitemid 34272274)
51. I.C. Munch, B. Sander, and L. Kessel Heredity of small hard drusen in twins aged 2046 years Invest Ophthalmol Vis Sci 48 2007 833 838 (Pubitemid 351260720)
52. S.H. Liew, C.E. Gilbert, and T.D. Spector Heritability of macular pigment: a twin study Invest Ophthalmol Vis Sci 46 2005 4430 4436 (Pubitemid 44264535)