Apoptosis of retinal photoreceptors during development in vitro: Protective effect of docosahexaenoic acid

Journal of Neurochemistry

Volumn 69, Issue 2, 1997, Pages 504-513

  Rotstein, Nora P ^a   Aveldańo, Marta I ^a   Barrantes, Francisco J ^a   Roccamo, Ana M ^a   Politi, Luis E ^a  

^a UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

Author keywords

Apoptosis; Docosahexaenoic acid; Programmed cell death; Retinal photoreceptors

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; FATTY ACID; OLEIC ACID; PALMITIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; NERVE CELL CULTURE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RAT; RETINA CELL;

ANIMALIA;

EID: 0030807556     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69020504.x     Document Type: Article

References (44)

1. Abrams, L., Politi L. E., and Adler R. (1989) Differential susceptibility of isolated mouse retinal neurons and photoreceptors to kainic acid toxicity. Invest. Ophthalmol. Vis. Sci. 30, 2300-2308.
2. Adler R. (1982) Regulation of neunte growth in purified retina cultures. Effects of PNPF: a substrate-bound neurite-promoting factor. J. Neurosci. Res. 8, 165-177.
3. Adler R. (1986) Trophic interactions in retinal development and in retinal degeneration: in vivo and in vitro studies, in The Retina: A Model for Cell Biology Studies, Part I (Adler R. and Farber D., eds), pp. 112-150. Academic Press, Orlando, Florida.
4. Akagawa K. and Barnstable C. J. (1986) Identification and characterization of cell types in monolayer cultures of rat retina using monoclonal antibodies. Brain Res. 383, 110-120.
5. Allsopp T. (1993) Life and death in the nervous system. Trends Neurosci. 16, 1-3.
6. Anderson R. E., Maude M. B., Lewis R. A., Newsome D. A., and Fishman G. A. (1987) Abnormal plasma levels of polyunsaturated fatty acid in autosomal dominant retinitis pigmentosa. Exp. Eye Res. 44, 155-159.
7. Appel S. (1981) A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism and Alzheimer's diseases. Ann. Neurol. 10, 499-505.
8. Aveldaño M. I. (1988) Phospholipid species containing long and very long chain polyenoic fatty acids remain with rhodopsin after hexane extraction of photoreceptor membranes. Biochemistry 27, 1229-1239.
9. 14C]docosahexaenoic acid by human platelets. J. Biol. Chem. 258, 9339-9343.
10. Barnstable C. J. (1980) Monoclonal antibodies which recognize different cell types in the rat retina. Nature 286, 231-235.
11. Bazán N. G., Birkle D. L., and Reddy T. S. (1984) Docosahexaenoic acid (22:6n-3) is metabolized to lipoxygenase reaction products in the retina. Biochem. Biophys. Res. Commun. 125, 741-747.
12. Bazán N. G., Scott B. L., Reddy T. S., and Pelias M. Z. (1986) Decreased content of docosahexaenoate and arachidonoate in plasma phospholipids in Usher's syndrome. Biochem. Biophys. Res. Commun. 141, 600-604.
13. Chang G.-Q., Hao Y., and Wong F. (1993) Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 11, 595-605.
14. Converse C. A., Hammer H. M., Packard C. J., and Shepherd J. (1983) Plasma lipid abnormalities in retinitis pigmentosa and related conditions. Trans. Ophthalmol. Soc. UK 103, 508-512.
15. Copani A., Bruno V. M. G., Barresi V., Battaglia G., Condorelli D. F., and Nicoletti F. (1995) Activation of metabotropic glutamate receptors prevents neuronal apoptosis in culture. J. Neurochem. 64, 101-108.
16. 2 and activation of protein kinase C. J. Biol. Chem. 269, 27258-27263.
17. Davies A. M. (1994) Intrinsic programmes of growth and survival in developing vertebrate neurons. Trends Neurosci. 17, 195-198.
18. Fekete D. M. and Barnstable C. J. (1983) The subcellular localization of rat photoreceptor-specific antigens. J. Neurocytol. 12, 785-803.
19. Hicks D. and Barnstable C. (1987) Different rhodopsin monoclonal antibodies reveal different binding patterns on developing and adult rat retina. J. Histochem. Cytochem. 35, 1317-1328.
20. Huang P. C., Gaitan A. E., Hao Y., Petters R. M., and Wong F. (1993) Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene. Proc. Natl. Acad. Sci. USA 90, 8484-8488.
21. Lauder J. M. (1993) Neurotransmitters as growth regulatory signals: role of receptors and second messengers. Trends Neurosci. 16, 233-239.
22. LaVail M. M., Unoki K., Yasumura D., Matthes M. T., Yancopoulos G. D., and Steinberg R. H. (1992) Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc. Natl. Acad. Sci. USA 89, 11249-11253.
23. Leonard D. S., Bowman V. D., Ready D. F., and Pak W. (1992) Photoreceptor degeneration associated with mutations in presumptive opsin structural gene of Drosophila. J. Neurobiol. 23, 605-626.
24. Lindsay R. M., Wiegand S. J., Altar C. A., and DiStefano P. S. (1994) Neurotrophic factors: from molecule to man. Trends Neurosci. 17, 182-190.
25. Politi L. E. and Adler R. (1988) Selective failure of long-term survival of isolated photoreceptors from both homozygous and heterozygous rd (retinal degeneration) mice. Exp. Eye Res. 47, 269-282.
26. Politi L. E., Lehar M., and Adler R. (1988) Development of neonatal mouse retinal neurons and photoreceptors in low density cell culture. Invest. Ophthalmol. Vis. Sci. 29, 534-543.
27. Politi L. E., Bouzat C. B., de los Santos E. B., and Barrantes F. J. (1996) Heterologous retinal cultured neurons and cell adhesion molecules induce clustering of acetylcholine receptors and polynucleation in mouse muscle BC3H-1 clonal cell line. J. Neurosci. Res. 43, 639-651.
28. Portera-Cailliau C., Sung C.-H., Nathans J., and Adler R. (1994) Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc. Natl. Acad. Sci. USA 91, 974-978.
29. Raff M. C. (1992) Social controls on cell survival and cell death. Nature 356, 397-400.
30. Raff M. C., Barres B. A., Burne J. F., Coles H. S., Ishizaki Y., and Jacobson M. D. (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262, 695-700.
31. Rao G. N., Baas A. S., Glasgow W. C., Eling T. E., Runge M. S., and Alexander R. W. (1994) Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells. J. Biol. Chem. 269, 32586-32591.
32. Rao V. R., Cohen G. B., and Oprian D. D. (1994) Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness. Nature 367, 639-642.
33. Rotstein N. P. and Aveldańo M. I. (1988) Synthesis of very long chain (up to 36 carbon) tetra, penta and hexaenoic fatty acids in retina. Biochem. J. 249, 191-200.
34. Rotstein N. P., Aveldano M. I., Barrantes F. J., and Politi L. E. (1996) Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro. J. Neurochem. 66, 1851-1859.
35. Schwartz L. M., Smith S. W., Jones M. E. E., and Osborne B. A. (1993) Do all programmed cell deaths occur via apoptosis? Proc. Natl. Acad. Sci. USA 90, 980-984.
36. Scott B. L., Racz E., Lolley R. N., and Bazán N. G. (1988) Developing rod photoreceptors from normal and mutant rd mouse retinas. Altered fatty acid composition early in development of the mutant. J. Neurosci. Res. 20, 202-211.
37. Steller H. (1995) Mechanisms and genes of cellular suicide. Science 26, 1445-1449.
38. Sung C.-H., Schneider B. G., Agarwal N., Papermaster D. S., and Nathans J. (1991) Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa. Proc. Natl. Acad. Sci. USA 88, 8840-8844.
39. Sung C.-H., Davenport C. M., and Nathans J. (1993) Rhodopsin mutants responsible for autosomal dominant retinitis pigmentosa. J. Biol. Chem. 268, 26645-26649.
40. Thompson C. G. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1460.
41. Van Rollins M., Baker R. C., Sprecher H. W., and Murphy R. C. (1984) Oxidation of docosahexaenoic acid by rat liver microsomes. J. Biol. Chem. 259, 5776-5783.
42. Vaux D. L. (1993) Toward an understanding of the molecular mechanisms of physiological cell death. Proc. Natl. Acad. Sci. USA 90, 786-789.
43. Wolfe L. S. (1982) Eicosanoids: prostaglandins, thromboxanes, leukotrienes and other derivatives of carbon-20 unsaturated fatty acids. J. Neurochem. 38, 1-14.
44. Young R. W. (1984) Cell death during differentiation of the retina in the mouse. J. Comp. Neurol. 229, 362-373.