Association between C-Reactive Protein and Age-Related Macular Degeneration

JAMA

Volumn 291, Issue 6, 2004, Pages 704-710

  Seddon, Johanna M ^a,b,e   Gensler, Gary ^c   Milton, Roy C ^c   Klein, Michael L ^d   Rifai, Nader ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c EMMES CORPORATION   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; C REACTIVE PROTEIN; MINERAL; VITAMIN; ZINC;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BODY MASS; CASE CONTROL STUDY; CONTROLLED STUDY; DEMOGRAPHY; DIET SUPPLEMENTATION; DRUSEN; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OPHTHALMOSCOPY; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; RISK FACTOR; SMOKING; STATISTICAL ANALYSIS; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DIAGNOSIS RELATED GROUP; INFLAMMATION; METABOLISM; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL; RETINA MACULA DEGENERATION;

AGED; AGED, 80 AND OVER; ANTIOXIDANTS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; DIAGNOSIS-RELATED GROUPS; DIETARY SUPPLEMENTS; FEMALE; HUMANS; INFLAMMATION; MACULAR DEGENERATION; MALE; MIDDLE AGED; RISK FACTORS; ZINC;

EID: 1442314663     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.291.6.704     Document Type: Article

References (21)

1. Seddon JM, Willett WC, Speizer FE, Hankinson SE. A prospective study of cigarette smoking and age-related macular degeneration in women. JAMA. 1996;276:1141-1146.
2. Smith W, Assink J, Klein R, et al. Risk factors for age-related macular degeneration: pooled findings from three continents. Ophthalmology. 2001;108:697-704.
3. Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration: Eye Disease Case-Control Study Group. JAMA. 1994;272:1413-1420.
4. Seddon JM, Rosner B, Sperduto RD, et al. Dietary fat and risk for advanced age-related macular degeneration. Arch Ophthalmol. 2001;119:1191-1199.
5. Cho E, Hung S, Willett W, et al. Prospective study of dietary fat and the risk of age-related macular degeneration. Am J Clin Nutr. 2001;73:209-218.
6. Seddon JM, Cote J, Rosner B. Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish Intake. Arch Ophthalmol. 2003;121:1728-1737.
7. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report 8. Arch Ophthalmol. 2001;119:1417-1436.
8. Seddon JM, Cote J, Davis N, Rosner B. Progression of age-related macular degeneration: association with body mass index, waist circumference and waist-hip ratio. Arch Ophthalmol. 2003;121:785-792.
9. Risk factors associated with age-related macular degeneration: a case-control study in the Age-Related Eye Disease Study: AREDS report 3. Ophthalmology. 2000;107:2224-2232.
10. The Eye Disease Case-Control Study Group. Risk factors for neovascular age-related macular degeneration. Arch Ophthalmol. 1992;110:1701-1708.
11. Snow K, Seddon J. Do age-related macular degeneration and cardiovascular disease share common antecedents? Ophthalmic Epidemiol. 1999;6:125-143.
12. Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA. 2001;285:2481-2485.
13. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation. 2003;107:363-369.
14. Hawkins B, Alexander J, Schachat A. Ocular Histoplasmosis: Retina. 3rd ed. Vol 2. St Louis, Mo: Mosby Inc; 2001:1687-1701.
15. Akiyama H, Barger S, Barnum S, et al. Inflammation and Aizheimer's disease. Neurobiol Aging. 2000;21:383-421.
16. The Age-Related Eye Disease Study (AREDS): design implications: AREDS report 1. Control Clin Trials. 1999;20:573-600.
17. McCarty CA, Lee SE, Livingston PM, Bissinella M, Taylor HR. Ocular exposure to UV-B in sunlight. Bull World Health Organ. 1996;74:353-360.
18. Klein R, Klein B, Marino E, et al. Early age-related maculopathy in the Cardiovascular Health Study. Ophthalmology. 2003;110:25-33.
19. Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002;134:411-431.
20. Ambati J, Anand A, Fernandez S, et al. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nat Med. 2003;9:1390-1397.
21. Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C-reactive protein levels in overweight and obese adults. JAMA. 1999;282:2131-2135.