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Volumn 12, Issue 3, 2014, Pages

Dual PDF Signaling Pathways Reset Clocks Via TIMELESS and Acutely Excite Target Neurons to Control Circadian Behavior

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CIRCADIAN RHYTHM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DROSOPHILA; DROSOPHILA PROTEINS; NERVE NET; NEURONS; NEUROPEPTIDES; SIGNAL TRANSDUCTION;

EID: 84899015909     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001810     Document Type: Article
Times cited : (96)

References (76)
  • 1
    • 80052900616 scopus 로고    scopus 로고
    • Molecular genetic analysis of circadian timekeeping in Drosophila
    • Hardin PE, (2011) Molecular genetic analysis of circadian timekeeping in Drosophila. Adv Genet 74: 141-173.
    • (2011) Adv Genet , vol.74 , pp. 141-173
    • Hardin, P.E.1
  • 2
    • 69749116301 scopus 로고    scopus 로고
    • An isoform-specific mutant reveals a role of PDP1epsilon in the circadian oscillator
    • Zheng X, Koh K, Sowcik M, Smith CJ, Chen D, et al. (2009) An isoform-specific mutant reveals a role of PDP1epsilon in the circadian oscillator. J Neurosci 29: 10920-10927.
    • (2009) J Neurosci , vol.29 , pp. 10920-10927
    • Zheng, X.1    Koh, K.2    Sowcik, M.3    Smith, C.J.4    Chen, D.5
  • 3
    • 0037423224 scopus 로고    scopus 로고
    • vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock
    • Cyran SA, Buchsbaum AM, Reddy KL, Lin MC, Glossop NR, et al. (2003) vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock. Cell 112: 329-341.
    • (2003) Cell , vol.112 , pp. 329-341
    • Cyran, S.A.1    Buchsbaum, A.M.2    Reddy, K.L.3    Lin, M.C.4    Glossop, N.R.5
  • 4
    • 34347382964 scopus 로고    scopus 로고
    • Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component
    • Kadener S, Stoleru D, McDonald M, Nawathean P, Rosbash M, (2007) Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component. Genes Dev 21: 1675-1686.
    • (2007) Genes Dev , vol.21 , pp. 1675-1686
    • Kadener, S.1    Stoleru, D.2    McDonald, M.3    Nawathean, P.4    Rosbash, M.5
  • 5
    • 34250215964 scopus 로고    scopus 로고
    • Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in Drosophila
    • Lim C, Chung BY, Pitman JL, McGill JJ, Pradhan S, et al. (2007) Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in Drosophila. Curr Biol 17: 1082-1089.
    • (2007) Curr Biol , vol.17 , pp. 1082-1089
    • Lim, C.1    Chung, B.Y.2    Pitman, J.L.3    McGill, J.J.4    Pradhan, S.5
  • 6
    • 34347375754 scopus 로고    scopus 로고
    • A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock
    • Matsumoto A, Ukai-Tadenuma M, Yamada RG, Houl J, Uno KD, et al. (2007) A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock. Genes Dev 21: 1687-1700.
    • (2007) Genes Dev , vol.21 , pp. 1687-1700
    • Matsumoto, A.1    Ukai-Tadenuma, M.2    Yamada, R.G.3    Houl, J.4    Uno, K.D.5
  • 7
    • 40849106529 scopus 로고    scopus 로고
    • The clockwork orange Drosophila protein functions as both an activator and a repressor of clock gene expression
    • Richier B, Michard-Vanhee C, Lamouroux A, Papin C, Rouyer F, (2008) The clockwork orange Drosophila protein functions as both an activator and a repressor of clock gene expression. J Biol Rhythms 23: 103-116.
    • (2008) J Biol Rhythms , vol.23 , pp. 103-116
    • Richier, B.1    Michard-Vanhee, C.2    Lamouroux, A.3    Papin, C.4    Rouyer, F.5
  • 8
    • 0038032878 scopus 로고    scopus 로고
    • A novel C-terminal domain of Drosophila PERIOD inhibits dCLOCK:CYCLE-mediated transcription
    • Chang DC, Reppert SM, (2003) A novel C-terminal domain of Drosophila PERIOD inhibits dCLOCK:CYCLE-mediated transcription. Curr Biol 13: 758-762.
    • (2003) Curr Biol , vol.13 , pp. 758-762
    • Chang, D.C.1    Reppert, S.M.2
  • 9
    • 34347356507 scopus 로고    scopus 로고
    • A small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization and transcriptional repressor activity
    • Nawathean P, Stoleru D, Rosbash M, (2007) A small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization and transcriptional repressor activity. Mol Cell Biol 27: 5002-5013.
    • (2007) Mol Cell Biol , vol.27 , pp. 5002-5013
    • Nawathean, P.1    Stoleru, D.2    Rosbash, M.3
  • 11
    • 0032486432 scopus 로고    scopus 로고
    • Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim
    • Darlington TK, Wager-Smith K, Ceriani MF, Staknis D, Gekakis N, et al. (1998) Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. Science 280: 1599-1603.
    • (1998) Science , vol.280 , pp. 1599-1603
    • Darlington, T.K.1    Wager-Smith, K.2    Ceriani, M.F.3    Staknis, D.4    Gekakis, N.5
  • 12
    • 30844466208 scopus 로고    scopus 로고
    • PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock
    • Meyer P, Saez L, Young MW, (2006) PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock. Science 311: 226-229.
    • (2006) Science , vol.311 , pp. 226-229
    • Meyer, P.1    Saez, L.2    Young, M.W.3
  • 13
    • 0029989521 scopus 로고    scopus 로고
    • Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock
    • Myers MP, Wagner-Smith K, Rothenfluh-Hilfiker A, Young MW, (1996) Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock. Science 271: 1736-1740.
    • (1996) Science , vol.271 , pp. 1736-1740
    • Myers, M.P.1    Wagner-Smith, K.2    Rothenfluh-Hilfiker, A.3    Young, M.W.4
  • 14
    • 0030293638 scopus 로고    scopus 로고
    • Regulation of nuclear entry of the Drosophila clock proteins period and timeless
    • Saez L, Young MW, (1996) Regulation of nuclear entry of the Drosophila clock proteins period and timeless. Neuron 17: 979-990.
    • (1996) Neuron , vol.17 , pp. 979-990
    • Saez, L.1    Young, M.W.2
  • 17
  • 18
    • 0032566970 scopus 로고    scopus 로고
    • The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila
    • Stanewsky R, Kaneko M, Emery P, Beretta B, Wager-Smith K, et al. (1998) The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila. Cell 95: 681-692.
    • (1998) Cell , vol.95 , pp. 681-692
    • Stanewsky, R.1    Kaneko, M.2    Emery, P.3    Beretta, B.4    Wager-Smith, K.5
  • 19
    • 33846102215 scopus 로고    scopus 로고
    • Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from Drosophila
    • Bae K, Edery I, (2006) Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from Drosophila. J Biochem (Tokyo) 140: 609-617.
    • (2006) J Biochem (Tokyo) , vol.140 , pp. 609-617
    • Bae, K.1    Edery, I.2
  • 20
    • 79955540602 scopus 로고    scopus 로고
    • NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed
    • Chiu JC, Ko HW, Edery I, (2011) NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed. Cell 145: 357-370.
    • (2011) Cell , vol.145 , pp. 357-370
    • Chiu, J.C.1    Ko, H.W.2    Edery, I.3
  • 21
    • 46249098507 scopus 로고    scopus 로고
    • The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock
    • Chiu JC, Vanselow JT, Kramer A, Edery I, (2008) The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock. Genes Dev 22: 1758-1772.
    • (2008) Genes Dev , vol.22 , pp. 1758-1772
    • Chiu, J.C.1    Vanselow, J.T.2    Kramer, A.3    Edery, I.4
  • 22
    • 84865791254 scopus 로고    scopus 로고
    • CULLIN-3 controls TIMELESS oscillations in the Drosophila circadian clock
    • Grima B, Dognon A, Lamouroux A, Chélot E, Rouyer F, (2012) CULLIN-3 controls TIMELESS oscillations in the Drosophila circadian clock. PLOS Biol 10: e1001367.
    • (2012) PLOS Biol , vol.10
    • Grima, B.1    Dognon, A.2    Lamouroux, A.3    Chélot, E.4    Rouyer, F.5
  • 23
    • 79958005498 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase CTRIP controls CLOCK levels and PERIOD oscillations in Drosophila
    • Lamaze A, Lamouroux A, Vias C, Hung HC, Weber F, et al. (2011) The E3 ubiquitin ligase CTRIP controls CLOCK levels and PERIOD oscillations in Drosophila. EMBO Rep 12: 549-557.
    • (2011) EMBO Rep , vol.12 , pp. 549-557
    • Lamaze, A.1    Lamouroux, A.2    Vias, C.3    Hung, H.C.4    Weber, F.5
  • 24
    • 0033543596 scopus 로고    scopus 로고
    • A role for the proteasome in the light response of the timeless clock protein
    • Naidoo N, Song W, Hunter-Ensor M, Sehgal A, (1999) A role for the proteasome in the light response of the timeless clock protein. Science 285: 1737-1741.
    • (1999) Science , vol.285 , pp. 1737-1741
    • Naidoo, N.1    Song, W.2    Hunter-Ensor, M.3    Sehgal, A.4
  • 26
    • 1342285689 scopus 로고    scopus 로고
    • Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A
    • Sathyanarayanan S, Zheng X, Xiao R, Sehgal A, (2004) Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A. Cell 116: 603-615.
    • (2004) Cell , vol.116 , pp. 603-615
    • Sathyanarayanan, S.1    Zheng, X.2    Xiao, R.3    Sehgal, A.4
  • 27
    • 77951912759 scopus 로고    scopus 로고
    • Circadian organization of behavior and physiology in Drosophila
    • Allada R, Chung BY, (2010) Circadian organization of behavior and physiology in Drosophila. Annu Rev Physiol 72: 605-624.
    • (2010) Annu Rev Physiol , vol.72 , pp. 605-624
    • Allada, R.1    Chung, B.Y.2
  • 28
    • 0034724292 scopus 로고    scopus 로고
    • Differential regulation of circadian pacemaker output by separate clock genes in Drosophila
    • Park JH, Helfrich-Forster C, Lee G, Liu L, Rosbash M, et al. (2000) Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. Proc Natl Acad Sci U S A 97: 3608-3613.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3608-3613
    • Park, J.H.1    Helfrich-Forster, C.2    Lee, G.3    Liu, L.4    Rosbash, M.5
  • 29
    • 84865743518 scopus 로고    scopus 로고
    • Autoreceptor control of peptide/neurotransmitter corelease from PDF neurons determines allocation of circadian activity in drosophila
    • Choi C, Cao G, Tanenhaus AK, McCarthy EV, Jung M, et al. (2012) Autoreceptor control of peptide/neurotransmitter corelease from PDF neurons determines allocation of circadian activity in drosophila. Cell Rep 2: 332-344.
    • (2012) Cell Rep , vol.2 , pp. 332-344
    • Choi, C.1    Cao, G.2    Tanenhaus, A.K.3    McCarthy, E.V.4    Jung, M.5
  • 30
    • 74949097778 scopus 로고    scopus 로고
    • PDF-modulated visual inputs and cryptochrome define diurnal behavior in Drosophila
    • Cusumano P, Klarsfeld A, Chelot E, Picot M, Richier B, et al. (2009) PDF-modulated visual inputs and cryptochrome define diurnal behavior in Drosophila. Nat Neurosci 12: 1431-1437.
    • (2009) Nat Neurosci , vol.12 , pp. 1431-1437
    • Cusumano, P.1    Klarsfeld, A.2    Chelot, E.3    Picot, M.4    Richier, B.5
  • 31
    • 84863664308 scopus 로고    scopus 로고
    • The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila
    • Duvall LB, Taghert PH, (2012) The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila. PLoS Biol 10: e1001337.
    • (2012) PLoS Biol , vol.10
    • Duvall, L.B.1    Taghert, P.H.2
  • 32
    • 36249006061 scopus 로고    scopus 로고
    • Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo
    • Harrisingh MC, Wu Y, Lnenicka GA, Nitabach MN, (2007) Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo. J Neurosci 27: 12489-12499.
    • (2007) J Neurosci , vol.27 , pp. 12489-12499
    • Harrisingh, M.C.1    Wu, Y.2    Lnenicka, G.A.3    Nitabach, M.N.4
  • 33
    • 26944502709 scopus 로고    scopus 로고
    • Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF
    • Hyun S, Lee Y, Hong ST, Bang S, Paik D, et al. (2005) Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF. Neuron 48: 267-278.
    • (2005) Neuron , vol.48 , pp. 267-278
    • Hyun, S.1    Lee, Y.2    Hong, S.T.3    Bang, S.4    Paik, D.5
  • 34
    • 26944456961 scopus 로고    scopus 로고
    • A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior
    • Lear BC, Merrill CE, Lin JM, Schroeder A, Zhang L, et al. (2005) A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior. Neuron 48: 221-227.
    • (2005) Neuron , vol.48 , pp. 221-227
    • Lear, B.C.1    Merrill, C.E.2    Lin, J.M.3    Schroeder, A.4    Zhang, L.5
  • 35
    • 68049147714 scopus 로고    scopus 로고
    • The neuropeptide PDF acts directly on evening pacemaker neurons to regulate multiple features of circadian behavior
    • Lear BC, Zhang L, Allada R, (2009) The neuropeptide PDF acts directly on evening pacemaker neurons to regulate multiple features of circadian behavior. PLoS Biol 7: e1000154.
    • (2009) PLoS Biol , vol.7
    • Lear, B.C.1    Zhang, L.2    Allada, R.3
  • 36
    • 26944486625 scopus 로고    scopus 로고
    • PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors
    • Mertens I, Vandingenen A, Johnson EC, Shafer OT, Li W, et al. (2005) PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors. Neuron 48: 213-219.
    • (2005) Neuron , vol.48 , pp. 213-219
    • Mertens, I.1    Vandingenen, A.2    Johnson, E.C.3    Shafer, O.T.4    Li, W.5
  • 37
    • 0033599009 scopus 로고    scopus 로고
    • A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
    • Renn SC, Park JH, Rosbash M, Hall JC, Taghert PH, (1999) A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell 99: 791-802.
    • (1999) Cell , vol.99 , pp. 791-802
    • Renn, S.C.1    Park, J.H.2    Rosbash, M.3    Hall, J.C.4    Taghert, P.H.5
  • 38
    • 77949512736 scopus 로고    scopus 로고
    • RNA-interference knockdown of Drosophila pigment dispersing factor in neuronal subsets: the anatomical basis of a neuropeptide's circadian functions
    • Shafer OT, Taghert PH, (2009) RNA-interference knockdown of Drosophila pigment dispersing factor in neuronal subsets: the anatomical basis of a neuropeptide's circadian functions. PLoS ONE 4: e8298.
    • (2009) PLoS ONE , vol.4
    • Shafer, O.T.1    Taghert, P.H.2
  • 39
    • 7244242193 scopus 로고    scopus 로고
    • Coupled oscillators control morning and evening locomotor behaviour of Drosophila
    • Stoleru D, Peng Y, Agosto J, Rosbash M, (2004) Coupled oscillators control morning and evening locomotor behaviour of Drosophila. Nature 431: 862-868.
    • (2004) Nature , vol.431 , pp. 862-868
    • Stoleru, D.1    Peng, Y.2    Agosto, J.3    Rosbash, M.4
  • 40
    • 40849134063 scopus 로고    scopus 로고
    • Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila
    • Wu Y, Cao G, Nitabach MN, (2008) Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila. J Biol Rhythms 23: 117-128.
    • (2008) J Biol Rhythms , vol.23 , pp. 117-128
    • Wu, Y.1    Cao, G.2    Nitabach, M.N.3
  • 41
    • 77950495934 scopus 로고    scopus 로고
    • DN1(p) circadian neurons coordinate acute light and PDF inputs to produce robust daily behavior in Drosophila
    • Zhang L, Chung BY, Lear BC, Kilman VL, Liu Y, et al. (2010) DN1(p) circadian neurons coordinate acute light and PDF inputs to produce robust daily behavior in Drosophila. Curr Biol 20: 591-599.
    • (2010) Curr Biol , vol.20 , pp. 591-599
    • Zhang, L.1    Chung, B.Y.2    Lear, B.C.3    Kilman, V.L.4    Liu, Y.5
  • 42
  • 43
    • 4544363312 scopus 로고    scopus 로고
    • The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system
    • Lin Y, Stormo GD, Taghert PH, (2004) The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system. J Neurosci 24: 7951-7957.
    • (2004) J Neurosci , vol.24 , pp. 7951-7957
    • Lin, Y.1    Stormo, G.D.2    Taghert, P.H.3
  • 44
    • 61449178808 scopus 로고    scopus 로고
    • The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clock
    • Yoshii T, Wulbeck C, Sehadova H, Veleri S, Bichler D, et al. (2009) The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clock. J Neurosci 29: 2597-2610.
    • (2009) J Neurosci , vol.29 , pp. 2597-2610
    • Yoshii, T.1    Wulbeck, C.2    Sehadova, H.3    Veleri, S.4    Bichler, D.5
  • 45
    • 19444384153 scopus 로고    scopus 로고
    • Pigment-dispersing factor and GABA synchronize cells of the isolated circadian clock of the cockroach Leucophaea maderae
    • Schneider NL, Stengl M, (2005) Pigment-dispersing factor and GABA synchronize cells of the isolated circadian clock of the cockroach Leucophaea maderae. J Neurosci 25: 5138-5147.
    • (2005) J Neurosci , vol.25 , pp. 5138-5147
    • Schneider, N.L.1    Stengl, M.2
  • 46
    • 77952168831 scopus 로고    scopus 로고
    • PDF receptor expression reveals direct interactions between circadian oscillators in Drosophila
    • Im SH, Taghert PH, (2010) PDF receptor expression reveals direct interactions between circadian oscillators in Drosophila. J Comp Neurol 518: 1925-1945.
    • (2010) J Comp Neurol , vol.518 , pp. 1925-1945
    • Im, S.H.1    Taghert, P.H.2
  • 47
    • 42149175153 scopus 로고    scopus 로고
    • Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging
    • Shafer OT, Kim DJ, Dunbar-Yaffe R, Nikolaev VO, Lohse MJ, et al. (2008) Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging. Neuron 58: 223-237.
    • (2008) Neuron , vol.58 , pp. 223-237
    • Shafer, O.T.1    Kim, D.J.2    Dunbar-Yaffe, R.3    Nikolaev, V.O.4    Lohse, M.J.5
  • 48
    • 0024375582 scopus 로고
    • cAMP-dependent protein kinase. Model for an enzyme family
    • Taylor SS, (1989) cAMP-dependent protein kinase. Model for an enzyme family. J Biol Chem 264: 8443-8446.
    • (1989) J Biol Chem , vol.264 , pp. 8443-8446
    • Taylor, S.S.1
  • 49
    • 0030768056 scopus 로고    scopus 로고
    • Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function
    • Majercak J, Kalderon D, Edery I, (1997) Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function. Mol Cell Biol 17: 5915-5922.
    • (1997) Mol Cell Biol , vol.17 , pp. 5915-5922
    • Majercak, J.1    Kalderon, D.2    Edery, I.3
  • 50
    • 0034617078 scopus 로고    scopus 로고
    • Type II cAMP-dependent protein kinase-deficient Drosophila are viable but show developmental, circadian, and drug response phenotypes
    • Park SK, Sedore SA, Cronmiller C, Hirsh J, (2000) Type II cAMP-dependent protein kinase-deficient Drosophila are viable but show developmental, circadian, and drug response phenotypes. J Biol Chem 275: 20588-20596.
    • (2000) J Biol Chem , vol.275 , pp. 20588-20596
    • Park, S.K.1    Sedore, S.A.2    Cronmiller, C.3    Hirsh, J.4
  • 51
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand AH, Perrimon N, (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 52
    • 0028897883 scopus 로고
    • Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development
    • Li W, Ohlmeyer JT, Lane ME, Kalderon D, (1995) Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development. Cell 80: 553-562.
    • (1995) Cell , vol.80 , pp. 553-562
    • Li, W.1    Ohlmeyer, J.T.2    Lane, M.E.3    Kalderon, D.4
  • 53
    • 0026679892 scopus 로고
    • Raf functions downstream of Ras1 in the Sevenless signal transduction pathway
    • Dickson B, Sprenger F, Morrison D, Hafen E, (1992) Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360: 600-603.
    • (1992) Nature , vol.360 , pp. 600-603
    • Dickson, B.1    Sprenger, F.2    Morrison, D.3    Hafen, E.4
  • 54
    • 29144447019 scopus 로고    scopus 로고
    • The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker
    • Lear BC, Lin JM, Keath JR, McGill JJ, Raman IM, et al. (2005) The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker. Neuron 48: 965-976.
    • (2005) Neuron , vol.48 , pp. 965-976
    • Lear, B.C.1    Lin, J.M.2    Keath, J.R.3    McGill, J.J.4    Raman, I.M.5
  • 55
    • 7244252844 scopus 로고    scopus 로고
    • Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain
    • Grima B, Chelot E, Xia R, Rouyer F, (2004) Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain. Nature 431: 869-873.
    • (2004) Nature , vol.431 , pp. 869-873
    • Grima, B.1    Chelot, E.2    Xia, R.3    Rouyer, F.4
  • 56
    • 33644589701 scopus 로고    scopus 로고
    • PDF cycling in the dorsal protocerebrum of the Drosophila brain is not necessary for circadian clock function
    • Kula E, Levitan ES, Pyza E, Rosbash M, (2006) PDF cycling in the dorsal protocerebrum of the Drosophila brain is not necessary for circadian clock function. J Biol Rhythms 21: 104-117.
    • (2006) J Biol Rhythms , vol.21 , pp. 104-117
    • Kula, E.1    Levitan, E.S.2    Pyza, E.3    Rosbash, M.4
  • 57
    • 38749109672 scopus 로고    scopus 로고
    • GFP Reconstitution Across Synaptic Partners (GRASP) defines cell contacts and synapses in living nervous systems
    • Feinberg EH, Vanhoven MK, Bendesky A, Wang G, Fetter RD, et al. (2008) GFP Reconstitution Across Synaptic Partners (GRASP) defines cell contacts and synapses in living nervous systems. Neuron 57: 353-363.
    • (2008) Neuron , vol.57 , pp. 353-363
    • Feinberg, E.H.1    Vanhoven, M.K.2    Bendesky, A.3    Wang, G.4    Fetter, R.D.5
  • 58
    • 4444377903 scopus 로고    scopus 로고
    • Novel single chain cAMP sensors for receptor-induced signal propagation
    • Nikolaev VO, Bunemann M, Hein L, Hannawacker A, Lohse MJ, (2004) Novel single chain cAMP sensors for receptor-induced signal propagation. J Biol Chem 279: 37215-37218.
    • (2004) J Biol Chem , vol.279 , pp. 37215-37218
    • Nikolaev, V.O.1    Bunemann, M.2    Hein, L.3    Hannawacker, A.4    Lohse, M.J.5
  • 59
    • 84880427381 scopus 로고    scopus 로고
    • Ultrasensitive fluorescent proteins for imaging neuronal activity
    • Chen TW, Wardill TJ, Sun Y, Pulver SR, Renninger SL, et al. (2013) Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature 499: 295-300.
    • (2013) Nature , vol.499 , pp. 295-300
    • Chen, T.W.1    Wardill, T.J.2    Sun, Y.3    Pulver, S.R.4    Renninger, S.L.5
  • 60
    • 33645313112 scopus 로고    scopus 로고
    • CNG and HCN channels: two peas, one pod
    • Craven KB, Zagotta WN, (2006) CNG and HCN channels: two peas, one pod. Annu Rev Physiol 68: 375-401.
    • (2006) Annu Rev Physiol , vol.68 , pp. 375-401
    • Craven, K.B.1    Zagotta, W.N.2
  • 61
    • 67649214496 scopus 로고    scopus 로고
    • Perturbing dynamin reveals potent effects on the Drosophila circadian clock
    • Kilman VL, Zhang L, Meissner RA, Burg E, Allada R, (2009) Perturbing dynamin reveals potent effects on the Drosophila circadian clock. PLoS ONE 4: e5235.
    • (2009) PLoS ONE , vol.4
    • Kilman, V.L.1    Zhang, L.2    Meissner, R.A.3    Burg, E.4    Allada, R.5
  • 62
    • 84867891647 scopus 로고    scopus 로고
    • Electrical activity can impose time of day on the circadian transcriptome of pacemaker neurons
    • Mizrak D, Ruben M, Myers GN, Rhrissorrakrai K, Gunsalus KC, et al. (2012) Electrical activity can impose time of day on the circadian transcriptome of pacemaker neurons. Curr Biol 22: 1871-1880.
    • (2012) Curr Biol , vol.22 , pp. 1871-1880
    • Mizrak, D.1    Ruben, M.2    Myers, G.N.3    Rhrissorrakrai, K.4    Gunsalus, K.C.5
  • 63
    • 0027996648 scopus 로고
    • Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce
    • Levine JD, Casey CI, Kalderon DD, Jackson FR, (1994) Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce. Neuron 13: 967-974.
    • (1994) Neuron , vol.13 , pp. 967-974
    • Levine, J.D.1    Casey, C.I.2    Kalderon, D.D.3    Jackson, F.R.4
  • 64
    • 84862828137 scopus 로고    scopus 로고
    • Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations
    • Luo W, Chen WF, Yue Z, Chen D, Sowcik M, et al. (2012) Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations. Aging Cell 11: 428-438.
    • (2012) Aging Cell , vol.11 , pp. 428-438
    • Luo, W.1    Chen, W.F.2    Yue, Z.3    Chen, D.4    Sowcik, M.5
  • 65
    • 84876076662 scopus 로고    scopus 로고
    • GW182 controls Drosophila circadian behavior and PDF-receptor signaling
    • Zhang Y, Emery P, (2013) GW182 controls Drosophila circadian behavior and PDF-receptor signaling. Neuron 78: 152-165.
    • (2013) Neuron , vol.78 , pp. 152-165
    • Zhang, Y.1    Emery, P.2
  • 66
    • 76749085755 scopus 로고    scopus 로고
    • Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA
    • Menet JS, Abruzzi KC, Desrochers J, Rodriguez J, Rosbash M, (2010) Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA. Genes Dev 24: 358-367.
    • (2010) Genes Dev , vol.24 , pp. 358-367
    • Menet, J.S.1    Abruzzi, K.C.2    Desrochers, J.3    Rodriguez, J.4    Rosbash, M.5
  • 67
    • 33745101711 scopus 로고    scopus 로고
    • Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription
    • Weber F, Hung HC, Maurer C, Kay SA, (2006) Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription. J Neurochem 98: 248-257.
    • (2006) J Neurochem , vol.98 , pp. 248-257
    • Weber, F.1    Hung, H.C.2    Maurer, C.3    Kay, S.A.4
  • 68
    • 0029979174 scopus 로고    scopus 로고
    • A light-entrainment mechanism for the Drosophila circadian clock
    • Zeng H, Qian Z, Myers MP, Rosbash M, (1996) A light-entrainment mechanism for the Drosophila circadian clock. Nature 380: 129-135.
    • (1996) Nature , vol.380 , pp. 129-135
    • Zeng, H.1    Qian, Z.2    Myers, M.P.3    Rosbash, M.4
  • 69
    • 0032126727 scopus 로고    scopus 로고
    • Evidence that the TIM light response is relevant to light-induced phase shifts in Drosophila melanogaster
    • Suri V, Qian Z, Hall JC, Rosbash M, (1998) Evidence that the TIM light response is relevant to light-induced phase shifts in Drosophila melanogaster. Neuron 21: 225-234.
    • (1998) Neuron , vol.21 , pp. 225-234
    • Suri, V.1    Qian, Z.2    Hall, J.C.3    Rosbash, M.4
  • 70
    • 71649101068 scopus 로고    scopus 로고
    • The CRYPTOCHROME photoreceptor gates PDF neuropeptide signaling to set circadian network hierarchy in Drosophila
    • Zhang L, Lear BC, Seluzicki A, Allada R, (2009) The CRYPTOCHROME photoreceptor gates PDF neuropeptide signaling to set circadian network hierarchy in Drosophila. Curr Biol 19: 2050-2055.
    • (2009) Curr Biol , vol.19 , pp. 2050-2055
    • Zhang, L.1    Lear, B.C.2    Seluzicki, A.3    Allada, R.4
  • 71
    • 59849096398 scopus 로고    scopus 로고
    • Motor control in a Drosophila taste circuit
    • Gordon MD, Scott K, (2009) Motor control in a Drosophila taste circuit. Neuron 61: 373-384.
    • (2009) Neuron , vol.61 , pp. 373-384
    • Gordon, M.D.1    Scott, K.2
  • 72
    • 56349125022 scopus 로고    scopus 로고
    • From the cover: feature article: light-arousal and circadian photoreception circuits intersect at the large PDF cells of the Drosophila brain
    • Shang Y, Griffith LC, Rosbash M, (2008) From the cover: feature article: light-arousal and circadian photoreception circuits intersect at the large PDF cells of the Drosophila brain. Proc Natl Acad Sci U S A 105: 19587-19594.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19587-19594
    • Shang, Y.1    Griffith, L.C.2    Rosbash, M.3
  • 73
    • 78249240868 scopus 로고    scopus 로고
    • Processing circadian data collected from the Drosophila Activity Monitoring (DAM) System
    • Pfeiffenberger C, Lear BC, Keegan KP, Allada R, (2010) Processing circadian data collected from the Drosophila Activity Monitoring (DAM) System. Cold Spring Harb Protoc 2010: pdb prot5519.
    • (2010) Cold Spring Harb Protoc , vol.2010 , pp. 5519
    • Pfeiffenberger, C.1    Lear, B.C.2    Keegan, K.P.3    Allada, R.4
  • 74
    • 73949101875 scopus 로고    scopus 로고
    • Dissecting differential gene expression within the circadian neuronal circuit of Drosophila
    • Nagoshi E, Sugino K, Kula E, Okazaki E, Tachibana T, et al. (2010) Dissecting differential gene expression within the circadian neuronal circuit of Drosophila. Nat Neurosci 13: 60-68.
    • (2010) Nat Neurosci , vol.13 , pp. 60-68
    • Nagoshi, E.1    Sugino, K.2    Kula, E.3    Okazaki, E.4    Tachibana, T.5
  • 75
    • 77955829612 scopus 로고    scopus 로고
    • Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila
    • Kula-Eversole E, Nagoshi E, Shang Y, Rodriguez J, Allada R, et al. (2010) Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila. Proc Natl Acad Sci U S A 107: 13497-13502.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13497-13502
    • Kula-Eversole, E.1    Nagoshi, E.2    Shang, Y.3    Rodriguez, J.4    Allada, R.5
  • 76
    • 0028483237 scopus 로고
    • Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions
    • Stewart BA, Atwood HL, Renger JJ, Wang J, Wu CF, (1994) Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J Comp Physiol A 175: 179-191.
    • (1994) J Comp Physiol A , vol.175 , pp. 179-191
    • Stewart, B.A.1    Atwood, H.L.2    Renger, J.J.3    Wang, J.4    Wu, C.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.