Synthesis, antimicrobial, and antioxidant activity of benzofuran barbitone and benzofuran thiobarbitone derivatives

Medicinal Chemistry Research

Volumn 23, Issue 6, 2014, Pages 3065-3081

  Kenchappa, R ^a   Bodke, Yadav D ^a   Asha, B ^a   Telkar, Sandeep ^a   Aruna Sindhe, M ^a  

^a KUVEMPU UNIVERSITY   (India)

Author keywords

Antimicrobial; Antioxidant; Barbiturates; Benzofuran; Docking; Knoevenagel condensation

Indexed keywords

5 [(2 BROMOPHENYL) (5 HYDROXY 1 BENZOFURAN 2 YL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [(2 BROMOPHENYL) (5 HYDROXY 1 BENZOFURAN 2 YL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(4 BROMOPHENYL) (5 HYDROXY 1 BENZOFURAN 2 YL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [(4 BROMOPHENYL) (5 HYDROXY 1 BENZOFURAN 2 YL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(5 BROMO 1 BENZOFURAN 2 YL) (2 BROMOPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [(5 BROMO 1 BENZOFURAN 2 YL) (2 BROMOPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(5 BROMO 1 BENZOFURAN 2 YL) (4 BROMOPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [(5 BROMO 1 BENZOFURAN 2 YL) (4 BROMOPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(5 BROMO 1 BENZOFURAN 2 YL) (4 METHOXYPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [(5 BROMO 1 BENZOFURAN 2 YL) (4 METHOXYPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(5 HYDROXY 1 BENZOFURAN 2 YL) (4 METHOXYPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [(5 HYDROXY 1 BENZOFURAN 2 YL) (4 METHOXYPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(BENZOFURAN 2 YL) (4 BROMOPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [(BENZOFURAN 2 YL) (4 METHOXYPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [1 BENZOFURAN 2 YL (2 BROMOPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [1 BENZOFURAN 2 YL (2 BROMOPHENYL)METHYLIDENE]PYRIMIDIN 2,4,6 (1H,3H,5H)TRIONE; 5 [1 BENZOFURAN 2 YL (4 BROMOPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; 5 [1 BENZOFURAN 2 YL (4 METHOXYPHENYL)METHYLIDENE] 2 THIOXODIHYDROPYRIMIDIN 4,6 (1H,5H)DIONE; ANTIINFECTIVE AGENT; ANTIOXIDANT; BENZOFURAN BARBITONE DERIVATIVE; BENZOFURAN DERIVATIVE; BENZOFURAN THIOBARBITONE DERIVATIVE; GLUTAMINE FRUCTOSE 6 PHOSPHATE AMINOTRANSFERASE; THIOBARBITURIC ACID; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL STRAIN; DRUG SYNTHESIS; FUNGAL STRAIN; IN VITRO STUDY; KNOEVENAGEL CONDENSATION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; NONHUMAN;

EID: 84898924793     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-013-0892-x     Document Type: Article

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