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Volumn 22, Issue 8, 2013, Pages 3911-3917

Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton's ascitic lymphoma in mice

Author keywords

Alanine amino transferase; Alkaline phosphatase; Aspartate amino transferase; Barbituric acid; Knoevenagel condensation; Total cholesterol

Indexed keywords

5 [(2) 1 (1H BENZIMIDAZOL 2 YL) 3 (3 NITROPHENYL) PROP 2 EN 1 YLIDENE]PYRIMIDINE 2,4,6 (1H,3H,5H) TRIONE; ANTINEOPLASTIC AGENT; FLUOROURACIL; UNCLASSIFIED DRUG;

EID: 84879498835     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0407-1     Document Type: Article
Times cited : (20)

References (23)
  • 1
    • 0034492435 scopus 로고    scopus 로고
    • Investigation of alkylating, antineoplastic and anti-HIV potentials of chalcone;2-(3- arylpropenoyl)benzimidazole and their corresponding N1-methyl derivatives
    • Aboul-Fadal TA, Elshorbagi AN, Hozien ZA, Wareth A, Sarhan AO (2000) Investigation of alkylating, antineoplastic and anti-HIV potentials of chalcone;2-(3- arylpropenoyl)benzimidazole and their corresponding N1-methyl derivatives. Boll Chim Farmac Anno 139:228-234
    • (2000) Boll Chim Farmac Anno , vol.139 , pp. 228-234
    • Aboul-Fadal, T.A.1    Elshorbagi, A.N.2    Hozien, Z.A.3    Wareth, A.4    Sarhan, A.O.5
  • 2
    • 0029038982 scopus 로고
    • Benzimidazole condensed ring.IX.Potential antineoplastics.New synthesis of some pyrido [12-a] benzimidazole and related derivatives
    • 1:CAS:528:DyaK2MXlvV2ht7k%3D
    • Badawey E, Kappe T (1995) Benzimidazole condensed ring.IX.Potential antineoplastics.New synthesis of some pyrido [12-a] benzimidazole and related derivatives. Eur J Med Chem 30:327-332
    • (1995) Eur J Med Chem , vol.30 , pp. 327-332
    • Badawey, E.1    Kappe, T.2
  • 3
    • 77955560958 scopus 로고    scopus 로고
    • Synthesis, antioxidant and DNA cleavage activities of novel indole derivatives
    • 20594623 1:CAS:528:DC%2BC3cXpvFKhtr4%3D
    • Biradar JS, Sasidhar BS, Praveen R (2010) Synthesis, antioxidant and DNA cleavage activities of novel indole derivatives. Eur J Med Chem 45:4074-4078
    • (2010) Eur J Med Chem , vol.45 , pp. 4074-4078
    • Biradar, J.S.1    Sasidhar, B.S.2    Praveen, R.3
  • 4
    • 61349177912 scopus 로고    scopus 로고
    • Design, synthesis and antitumor evaluation of novel bis-benzimidazoles
    • Cheng MS, Yang YH, Wang H, Liao N, Wang J, Chen H (2009) Design, synthesis and antitumor evaluation of novel bis-benzimidazoles. Eur J Med Chem 45:1808-1812
    • (2009) Eur J Med Chem , vol.45 , pp. 1808-1812
    • Cheng, M.S.1    Yang, Y.H.2    Wang, H.3    Liao, N.4    Wang, J.5    Chen, H.6
  • 5
    • 0028073419 scopus 로고
    • Benzimidazole, potent antimiotic drugs: Substrate for the P-glycoprotein transporter in multi-drug resistant drugs
    • 7811303
    • Georges E, Nare B, Prichard RK (1994) Benzimidazole, potent antimiotic drugs: Substrate for the P-glycoprotein transporter in multi-drug resistant drugs. Biochem Pharmacol 48:2215-2222
    • (1994) Biochem Pharmacol , vol.48 , pp. 2215-2222
    • Georges, E.1    Nare, B.2    Prichard, R.K.3
  • 8
    • 0032527952 scopus 로고    scopus 로고
    • Blood Lipid Profile in Children's with Acute Lymphoblastic Leukemia
    • Jacqueline MH, Darius JN, Mathew JM, Ronald DB (1998) Blood Lipid Profile in Children's with Acute Lymphoblastic Leukemia. Cancer 83:379-384
    • (1998) Cancer , vol.83 , pp. 379-384
    • Jacqueline, M.H.1    Darius, J.N.2    Mathew, J.M.3    Ronald, D.B.4
  • 9
    • 0037025755 scopus 로고    scopus 로고
    • Preparation of dibarbiturates of oxindole by condensation of isatin and barbituric acid derivatives
    • 1:CAS:528:DC%2BD38XlsVelsb4%3D
    • Jursic BS, Stevens ED (2002) Preparation of dibarbiturates of oxindole by condensation of isatin and barbituric acid derivatives. Tetrahedron Lett 43:5681-5683
    • (2002) Tetrahedron Lett , vol.43 , pp. 5681-5683
    • Jursic, B.S.1    Stevens, E.D.2
  • 10
    • 0036888778 scopus 로고    scopus 로고
    • Anticancer activity for 4,40-dihydroxybenzophenone-2,4- dinitrophenylhydrazone (A-007) analogues and their abilities to interact with Lymphoendothelial cell surface markers
    • 12419372
    • Jursic BS, Morgan LR, Hopper CL, Neumann DM, Thangaraj K, LeBalnc B (2002) Anticancer activity for 4,40-dihydroxybenzophenone-2,4- dinitrophenylhydrazone (A-007) analogues and their abilities to interact with Lymphoendothelial cell surface markers. Bioorg Med Chem Lett 12:3407-3411
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 3407-3411
    • Jursic, B.S.1    Morgan, L.R.2    Hopper, C.L.3    Neumann, D.M.4    Thangaraj, K.5    Lebalnc, B.6
  • 11
    • 55949118090 scopus 로고    scopus 로고
    • Jaypee Brothers Medical Publishers New Delhi, India
    • Mohan H (2006) Textbook of Pathology. Jaypee Brothers Medical Publishers, New Delhi, India
    • (2006) Textbook of Pathology
    • Mohan, H.1
  • 12
    • 0027525231 scopus 로고
    • 5-Benzyl barbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase
    • 8216379 1:CAS:528:DyaK2cXksFWqug%3D%3D
    • Naguib FNM, Levesque DL, Wang EC, Panzica RP, Kouni MH (1993) 5-Benzyl barbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase. Biochem Pharmacol 46:1273-1283
    • (1993) Biochem Pharmacol , vol.46 , pp. 1273-1283
    • Naguib, F.N.M.1    Levesque, D.L.2    Wang, E.C.3    Panzica, R.P.4    Kouni, M.H.5
  • 14
    • 77955843127 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of some novel-3-(5-substituted benzimidazole-2-yl)-5-aryl isoxazolines
    • 1:CAS:528:DC%2BC3cXhtVKitbvJ
    • Reddy VM, Reddy KR (2010a) Synthesis and biological evaluation of some novel-3-(5-substituted benzimidazole-2-yl)-5-aryl isoxazolines. Chin Chem Lett 21:1145-1148
    • (2010) Chin Chem Lett , vol.21 , pp. 1145-1148
    • Reddy, V.M.1    Reddy, K.R.2
  • 15
    • 77954275784 scopus 로고    scopus 로고
    • Synthesis and antimicrobial activity of some novel 4-(1H-Benz[d]imidazol- 1, 3-thiazol-2 amines
    • 1:CAS:528:DC%2BC3cXhtFert7zI
    • Reddy VM, Reddy KR (2010b) Synthesis and antimicrobial activity of some novel 4-(1H-Benz[d]imidazol-1, 3-thiazol-2 amines. Chem Pharm Bull 58:953-956
    • (2010) Chem Pharm Bull , vol.58 , pp. 953-956
    • Reddy, V.M.1    Reddy, K.R.2
  • 16
    • 33748945866 scopus 로고    scopus 로고
    • Synthesis and characterization of barbitones as antimicrobial agents
    • 1:CAS:528:DC%2BD28XpvFahsb8%3D
    • Sangani HG, Bhimani KB, Khunt RC (2006) Synthesis and characterization of barbitones as antimicrobial agents. J Serb Chem Soc 71:587-591
    • (2006) J Serb Chem Soc , vol.71 , pp. 587-591
    • Sangani, H.G.1    Bhimani, K.B.2    Khunt, R.C.3
  • 17
    • 84866307275 scopus 로고    scopus 로고
    • Anti tumor activity of Methanolic extract of Hypericum hookerianum on EAC Cell line in Swiss albino mice
    • Santhosh KH, Senthil KN, Reghu CH (2007) Anti tumor activity of Methanolic extract of Hypericum hookerianum on EAC Cell line in Swiss albino mice. J Pharmacological Sci 103:354-359
    • (2007) J Pharmacological Sci , vol.103 , pp. 354-359
    • Santhosh, K.H.1    Senthil, K.N.2    Reghu, C.H.3
  • 18
    • 72049105061 scopus 로고    scopus 로고
    • Pyrazoline bearing benzimidazole: Search for anticancer agent
    • 19883957 1:CAS:528:DC%2BD1MXhsF2ju7%2FM
    • Shaharyar M, Abdullah MM, Bakht MA, Majeed J (2010) Pyrazoline bearing benzimidazole: Search for anticancer agent. Eur J Med Chem 45:114-119
    • (2010) Eur J Med Chem , vol.45 , pp. 114-119
    • Shaharyar, M.1    Abdullah, M.M.2    Bakht, M.A.3    Majeed, J.4
  • 19
    • 0014143271 scopus 로고
    • Action of central nervous system stimulant and depressant drugs in the intact animal
    • 1:CAS:528:DyaF1cXjvVSjtw%3D%3D
    • Shulman VA, Laycock GM (1967) Action of central nervous system stimulant and depressant drugs in the intact animal. European J Pharmacol 2:17-25
    • (1967) European J Pharmacol , vol.2 , pp. 17-25
    • Shulman, V.A.1    Laycock, G.M.2
  • 20
    • 65149100170 scopus 로고    scopus 로고
    • Design, synthesis and anticancer activity of hybrids of indole and barbituric acid-Identification of highly promising leads
    • Sing P, Kaur M, Verma P (2009) Design, synthesis and anticancer activity of hybrids of indole and barbituric acid-Identification of highly promising leads. Bioorg Med Chem Lett 19:3054-3058
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 3054-3058
    • Sing, P.1    Kaur, M.2    Verma, P.3
  • 22
    • 53849108129 scopus 로고    scopus 로고
    • Facile synthesis of alkoxyphthalimide derivatized benzimidazole assembled pyrazole, pyrimidines and isoxazole via common intermediate chalcones
    • Talesara GL, Bapna A, Ojha S (2010) Facile synthesis of alkoxyphthalimide derivatized benzimidazole assembled pyrazole, pyrimidines and isoxazole via common intermediate chalcones. Indian J Chem 47B:1096-1107
    • (2010) Indian J Chem , vol.47 , pp. 1096-1107
    • Talesara, G.L.1    Bapna, A.2    Ojha, S.3
  • 23
    • 0025220007 scopus 로고
    • Tumor reducing and Anti-carcinogenic activity of selected species
    • 2110862 1:STN:280:DyaK3c3kvV2lsA%3D%3D
    • Unnikrishnan MC, Kuttan R (1990) Tumor reducing and Anti-carcinogenic activity of selected species. Cancer lett 51:85-89
    • (1990) Cancer Lett , vol.51 , pp. 85-89
    • Unnikrishnan, M.C.1    Kuttan, R.2


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