New heterocyclic compounds from 1,2,4-triazole and 1,3,4-thiadiazole class bearing diphenylsulfone moieties. Synthesis, characterization and antimicrobial activity evaluation

European Journal of Medicinal Chemistry

Volumn 49, Issue , 2012, Pages 417-423

  Barbuceanu, Stefania Felicia ^a   Saramet, Gabriel ^a   Almajan, Gabriela Laura ^a   Draghici, Constantin ^b   Barbuceanu, Florica ^c   Bancescu, Gabriela ^d  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b INSTITUTE OF ORGANIC CHEMISTRY   (Romania)

^c Institute for Diagnosis and Animal Health   (Romania)

^d Faculty of Dentistry   (Romania)

Author keywords

1,2,4 Triazol 3 thione; 1,3,4 Thiadiazol 2 amine; Acylthiosemicarbazide; Antimicrobial activity; Cyclization; Diphenylsulfone moiety

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 1,3,4 THIADIAZOLE DERIVATIVE; 5 [4 (4 BROMOPHENYLSULFONYL)PHENYL] 4 (4 TRIFLUOROMETHOXYPHENYL) 2H 1,2,4 TRIAZOL 3(4H) THIONE; 5 [4 (4 BROMOPHENYLSULFONYL)PHENYL] N (4 TRIFLUOROMETHOXYPHENYL) 1,3,4 THIADIAZOL 2 AMINE; 5 [4 (PHENYLSULFONYL)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) 2H 1,2,4 TRIAZOL 3(4H) THIONE; 5 [4 (PHENYLSULFONYL)PHENYL] 4 (4 TRIFLUOROMETHOXYPHENYL) 2H 1,2,4 TRIAZOL 3(4H) THIONE; 5 [4 (PHENYLSULFONYL)PHENYL] N (3,4,5 TRIMETHOXYPHENYL) 1,3,4 THIADIAZOL 2 AMINE; 5 [4 (PHENYLSULFONYL)PHENYL] N (4 TRIFLUOROMETHOXYPHENYL) 1,3,4 THIADIAZOL 2 AMINE; AMIKACIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; FLUCONAZOLE; N 1 [4 (4 BROMOPHENYLSULFONYL)BENZOYL] N 4 (3,4,5 TRIMETHOXYPHENYL)THIOSEMICARBAZIDE; N 1 [4 (4 BROMOPHENYLSULFONYL)BENZOYL] N 4 (4 TRIFLUOROMETHOXYPHENYL)THIOSEMICARBAZIDE; N 1 [4 (PHENYLSULFONYL)BENZOYL] N 4 (3,4,5 TRIMETHOXYPHENYL)THIOSEMICARBAZIDE; N 1 [4 (PHENYLSULFONYL)BENZOYL] N 4 (4 TRIFLUOROMETHOXYPHENYL)THIOSEMICARBAZIDE; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACILLUS CEREUS; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; MOLECULAR WEIGHT; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; YEAST;

ANTI-INFECTIVE AGENTS; BACTERIA; BACTERIAL INFECTIONS; FUNGI; HUMANS; MICROBIAL SENSITIVITY TESTS; MYCOSES; THIADIAZOLES; TRIAZOLES;

EID: 84857239414     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.01.031     Document Type: Article

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