Non-native soluble oligomers of Cu/Zn superoxide dismutase (SOD1) contain a conformational epitope linked to cytotoxicity in amyotrophic lateral sclerosis (ALS)

Biochemistry

Volumn 53, Issue 14, 2014, Pages 2423-2432

  Redler, Rachel L ^a   Fee, Lanette ^a   Fay, James M ^a   Caplow, Michael ^a   Dokholyan, Nikolay V ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXICITY; DIMERS; NEURODEGENERATIVE DISEASES; NEURONS; OXYGEN;

AMYOTROPHIC LATERAL SCLEROSIS; CELLULAR ENVIRONMENT; CONFORMATIONAL EPITOPES; CU/ZN-SUPEROXIDE DISMUTASE; NON-NATIVE SPECIES; OXIDATIVE MODIFICATION; STRUCTURAL SIMILARITY; THERAPEUTIC TARGETS;

EPITOPES;

AMYOTROPHIC LATERAL SCLEROSIS; BIOPOLYMERS; CHROMATOGRAPHY, GEL; EPITOPES; MOLECULAR WEIGHT; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE;

EID: 84898915667     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500158w     Document Type: Article

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