Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 15, 2014, Pages

  Yu, Anan ^a   Shibata, Yoko ^a   Shah, Bijal ^b   Calamini, Barbara ^b   Lo, Donald C ^b   Morimoto, Richard I ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chaperone Dependent Processes; Hsp70; Protein Misfolding; Proteostasis

Indexed keywords

AMPA RECEPTOR; ATAXIN 1; CHAPERONE; CLATHRIN; COPPER ZINC SUPEROXIDE DISMUTASE; HEAT SHOCK COGNATE PROTEIN 70; HUNTINGTIN; POLYGLUTAMINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; EMBRYO; ENDOCYTOSIS; HUMAN; HUMAN CELL; LOSS OF FUNCTION MUTATION; MAMMAL CELL; MOUSE; MUTANT; NERVE CELL; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; RISK ASSESSMENT;

CHAPERONE-DEPENDENT PROCESSES; HSP70; PROTEIN MISFOLDING; PROTEOSTASIS;

ANIMALS; ANTIBODY SPECIFICITY; BINDING, COMPETITIVE; CLATHRIN; CLONING, MOLECULAR; DNA PRIMERS; ENDOCYTOSIS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HSC70 HEAT-SHOCK PROTEINS; IMMUNOBLOTTING; MICE; MOLECULAR CHAPERONES; NEURONS; PLASMIDS; PROTEIN CONFORMATION; PROTEINS; RNA, SMALL INTERFERING;

EID: 84898779814     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321811111     Document Type: Article

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