Dietary arginine supplementation enhances intestinal expression of SLC7A7 and SLC7A1 and ameliorates growth depression in mycotoxin-challenged pigs

Amino Acids

Volumn 46, Issue 4, 2014, Pages 883-892

  Yin, Jie ^a,b   Ren, Wenkai ^a,b   Duan, Jielin ^a,b   Wu, Li ^a,b   Chen, Shuai ^a   Li, Tiejun ^a   Yin, Yulong ^a   Wu, Guoyao ^a,c,d  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c CHINA AGRICULTURAL UNIVERSITY   (China)

^d TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Arginine; Mycotoxin; Nutrition; Small intestine; Swine

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); AMINO ACID; ARGININE; BETA ACTIN; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTATHIONE PEROXIDASE; LACTIC ACID; MYCOTOXIN; SUPEROXIDE DISMUTASE; AMINO ACID TRANSPORTER; CD98 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; FEEDING; FOOD ANALYSIS; GENE; GENE EXPRESSION; GENE FUNCTION; GROWTH DISORDER; GROWTH RATE; ILEUM; JEJUNUM; LACTATE BLOOD LEVEL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SLC7A1 GENE; SLC7A7 GENE; SMALL INTESTINE DISEASE; SWINE; TISSUE STRUCTURE; UPREGULATION; WEIGHT GAIN; ANALYSIS; ANIMAL; ANIMAL FOOD; FEMALE; FOOD CONTAMINATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; PIG; SMALL INTESTINE;

ANIMAL FEED; ANIMALS; ANTIGENS, CD98 LIGHT CHAINS; ARGININE; CATIONIC AMINO ACID TRANSPORTER 1; DIETARY SUPPLEMENTS; FEMALE; FOOD CONTAMINATION; INTESTINE, SMALL; MALE; MYCOTOXINS; SWINE;

EID: 84898669954     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-013-1643-5     Document Type: Article

References (84)

1. Andretta I, Kipper M, Lehnen CR et al (2012) Meta-analytical study of productive and nutritional interactions of mycotoxins in growing pigs. Animal 6:1476-1482
2. Anggard E (1994) Nitric oxide: mediator, murderer, and medicine. Lancet 343:1199-1206
3. Applegate TJ, Schatzmayr G, Prickel K et al (2009) Effect of aflatoxin culture on intestinal function and nutrient loss in laying hens. Poult Sci 88:1235-1241
4. Aravind KL, Patil VS, Devegowda G et al (2003) Efficacy of esterified glucomannan to counteract mycotoxicosis in naturally contaminated feed on performance and serum biochemical and hematological parameters in broilers. Poult Sci 82:571-576
5. Awad WA, Bohm J, Razzazi-Fazeli E et al (2006) Effect of addition of a probiotic microorganism to broiler diets contaminated with deoxynivalenol on performance and histological alterations of intestinal villi of broiler chickens. Poult Sci 85:974-979
6. Binder EM (2007) Managing the risk of mycotoxins in modern feed production. Anim Feed Sci Technol 133:149-166
7. Binder EM, Tan LM, Chin LJ et al (2007) Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients. Anim Feed Sci Technol 137:265-282
8. Chaytor AC, Hansen JA, van Heugten E et al (2011) Occurrence and decontamination of mycotoxins in swine feed. Asian-Australas J Anim Sci 24:723-738
9. Dai ZL, Wu G, Zhu WY (2011) Amino acid metabolism in intestinal bacteria: links between gut ecology and host health. Front Biosci 16:1768-1786
10. Dai ZL, Li XL, Xi PB et al (2012a) Metabolism of select amino acids in bacteria from the pig small intestine. Amino Acids 42:1597-1608
11. Dai ZL, Li XL, Xi PB et al (2012b) Regulatory role for l-arginine in the utilization of amino acids by pig small-intestinal bacteria. Amino Acids 43:233-244
12. Dai ZL, Li XL, Xi PB et al (2013a) l-Glutamine regulates amino acid utilization by intestinal bacteria. Amino Acids 45:501-512
13. Dai ZL, Wu ZL, Yang Y et al (2013b) Nitric oxide and energy metabolism in mammals. BioFactors 39:383-391
14. Deng D, Yin YL, Chu WY et al (2009) Impaired translation initiation activation and reduced protein synthesis in weaned piglets fed a low-protein diet. J Nutr Biochem 20:544-552
15. Dinu D, Bodea GO, Ceapa CD et al (2011) Adapted response of the antioxidant defense system to oxidative stress induced by deoxynivalenol in Hek-293 cells. Toxicon 57:1023-1032
16. Fokunang CN, Tembe-Fokunang EA, Tomkins P et al (2006) Global impact of mycotoxins on human and animal health management. Outlook Agric 35:247-253
17. Fu WJ, Stromberg AJ, Viele K et al (2010) Statistics and bioinformatics in nutritional sciences: analysis of complex data in the era of systems biology. J Nutr Biochem 21:561-572
18. Guan S, Gong M, Yin YL et al (2011) Occurrence of mycotoxins in feeds and feed ingredients in China. J Food Agric Environ 9:163-167
19. He QH, Ren PP, Kong XF et al (2012) Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach. J Nutr Biochem 23:133-139
20. He LQ, Yang HS, Li TJ et al (2013a) Effects of dietary l-lysine intake on the intestinal mucosa and expression of CAT genes in weaned piglets. Amino Acids 45:383-391
21. He LQ, Yin YL, Li TJ et al (2013b) Use of the Ussing chamber technique to study nutrient transport by epithelial tissues. Front Biosci 18:1266-1274
22. Hou YQ, Wang L, Zhang W et al (2012) Protective effects of N-acetylcysteine on intestinal functions of piglets challenged with lipopolysaccharide. Amino Acids 43:1233-1242
23. Hou YQ, Wang L, Yi D et al (2013) N-Acetylcysteine reduces inflammation in the small intestine by regulating redox, EGF and TLR4 signaling. Amino Acids 45:513-522
24. Jiang SZ, Yang ZB, Yang WR et al (2011) Effects of purified zearalenone on growth performance, organ size, serum metabolites, and oxidative stress in postweaning gilts. J Anim Sci 89:3008-3015
25. Jobgen W, Fu WJ, Gao H et al (2009) High fat feeding and dietary l-arginine supplementation differentially regulate gene expression in rat white adipose tissue. Amino Acids 37:187-198
26. Kim SW, Wu G (2004) Dietary arginine supplementation enhances the growth of milk-fed young pigs. J Nutr 134:625-630
27. Kong X, Tan B, Yin Y et al (2012) l-arginine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. J Nutr Biochem 23:1178-1183
28. Koppelmann T, Pollak Y, Mogilner J et al (2012) Dietary l-arginine supplementation reduces methotrexate-induced intestinal mucosal injury in rat. BMC Gastroenterol 12:41
29. Lei J, Feng DY, Zhang YL et al (2012) Nutritional and regulatory role of branched-chain amino acids in lactation. Front Biosci 17:2725-2739
30. Li P, Yin YL, Li DF et al (2007) Amino acids and immune function. Br J Nutr 98:237-252
31. Li XL, Rezaei R, Li P et al (2011) Composition of amino acids in feed ingredients for animal diets. Amino Acids 40:1159-1168
32. Liu YL, Meng GQ, Wang HR et al (2011) Effect of three mycotoxin adsorbents on growth performance, nutrient retention and meat quality in broilers fed on mould-contaminated feed. Br Poult Sci 52:255-263
33. Liu XD, Wu X, Yin YL et al (2012) Effects of dietary l-arginine or N-carbamylglutamate supplementation during late gestation of sows on the miR-15b/16, miR-221/222, VEGFA and eNOS expression in umbilical vein. Amino Acids 42:2111-2119
34. Maresca M, Mahfoud R, Garmy N et al (2002) The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. J Nutr 132:2723-2731
35. Mary VS, Theumer MG, Arias SL et al (2012) Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells. Toxicology 302:299-307
36. Packer RA, Moore GE, Chang CY et al (2012) Serum d-lactate concentrations in cats with gastrointestinal disease. J Vet Intern Med 26:905-910
37. Park BJ, Takatori K, Sugita-Konishi Y et al (2007) Degradation of mycotoxins using microwave-induced argon plasma at atmospheric pressure. Surf Coat Technol 201:5733-5737
38. Ren W, Luo W, Wu M et al (2011) Dietary l-glutamine supplementation improves pregnancy outcome in mice infected with type-2 porcine circovirus. Amino Acids 45:479-488
39. Ren W, Yin YL, Liu G et al (2012) Effect of dietary arginine supplementation on reproductive performance of mice with porcine circovirus type 2 infection. Amino Acids 42:2089-2094
40. Rezaei R, Knabe DA, Wu G (2013a) Impact of aflatoxins on swine nutrition and possible measures of control and amelioration. Aflatoxin control: safeguarding animal feed with calcium smectite. In: Joe B. Dixon, Ana L. Barrientos Velázquez, Youjun Deng, (eds) American Society of Agronomy and Soil Science, Madison, pp 54-67. doi: 10.2136/2013.aflatoxins.c6
41. Rezaei R, Knabe DA, Tekwe CD et al (2013b) Dietary supplementation with monosodium glutamate is safe and improves growth performance in postweaning pigs. Amino Acids 44:911-923
42. Rhoads JM, Wu G (2009) Glutamine, arginine, and leucine signaling in the intestine. Amino Acids 37:111-122
43. Rhoads JM, Liu Y, Niu X et al (2008) Arginine stimulates cdx2-transformed intestinal epithelial cell migration via a mechanism requiring both nitric oxide and phosphorylation of p70 S6 kinase. J Nutr 138:1652-1657
44. Richard JL et al (2007) Some major mycotoxins and their mycotoxicoses - an overview. Int J Food Microbiol 119:3-10
45. Ruan Z, Lv YF, Fu XF et al (2013) Metabolomic analysis of amino acid metabolism in colitic rats supplemented with lactosucrose. Amino Acids 45:877-887
46. Stechmiller JK, Childress B, Cowan L et al (2005) Arginine supplementation and wound healing. Nutr Clin Pract 20:52-61
47. Swamy HVLN, Smith TK, MacDonald EJ et al (2003) Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on growth and immunological measurements of starter pigs, and the efficacy of a polymeric glucomannan mycotoxin adsorbent. J Anim Sci 81:2792-2803
48. Tan BE, Yin YL, Liu ZQ et al (2009) Dietary l-arginine supplementation increases muscle gain and reduces body fat mass in growing-finishing pigs. Amino Acids 37:169-175
49. Tan BE, Yin YL, Kong XF et al (2010) l-Arginine stimulates proliferation and prevents endotoxin-induced death of intestinal cells. Amino Acids 38:1227-1235
50. Tan B, Li X, Wu G et al (2012a) Dynamic changes in blood flow and oxygen consumption in the portal-drained viscera of growing pigs receiving acute administration of l-arginine. Amino Acids 43:2481-2489
51. Tan BE, Li XG, Yin YL et al (2012b) Regulatory roles for l-arginine in reducing white adipose tissue. Front Biosci 17:2237-2246
52. Wang JJ, Chen LX, Li P et al (2008) Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation. J Nutr 138:1025-1032
53. Wang XQ, Ou DY, Yin JD et al (2009) Proteomic analysis reveals altered expression of proteins related to glutathione metabolism and apoptosis in the small intestine of zinc oxide-supplemented piglets. Amino Acids 37:209-218
54. Wang WW, Wu ZL, Dai ZL et al (2013) Glycine metabolism in animals and humans: implications for nutrition and health. Amino Acids 45:463-477
55. Wei JW, Carroll RJ, Harden KK et al (2012) Comparisons of treatment means when factors do not interact in two-factorial studies. Amino Acids 42:2031-2035
56. Wu G (2009) Amino acids: metabolism, functions, and nutrition. Amino Acids 37:1-17
57. Wu G (2010a) Recent advances in swine amino acid nutrition. J Anim Sci Biotechnol 1:49-61
58. Wu G (2010b) Functional amino acids in growth, reproduction and health. Adv Nutr 1:31-37
59. Wu G (2013a) Functional amino acids in nutrition and health. Amino Acids 45:407-411
60. Wu G (2013b) Amino acids: biochemistry and nutrition. CRC Press, Boca Raton
61. Wu G, Knabe DA (1995) Arginine synthesis in enterocytes of neonatal pigs. Am J Physiol Regul Integr Comp Physiol 269:R621-R629
62. Wu G, Morris SM Jr (1998) Arginine metabolism: nitric oxide and beyond. Biochem J 336:1-17
63. Wu G, Knabe DA, Flynn NE (1994) Synthesis of citrulline from glutamine in pig enterocytes. Biochem J 299:115-121
64. Wu G, Meier SA, Knabe DA (1996a) Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. J Nutr 126:2578-2584
65. Wu G, Knabe DA, Flynn NE et al (1996b) Arginine degradation in developing porcine enterocytes. Am J Physiol Gastrointest Liver Physiol 271:G913-G919
66. Wu G, Collins JK, Perkins-Veazie P et al (2007a) Dietary supplementation with watermelon pomace juice enhances arginine availability and ameliorates the metabolic syndrome in Zucker diabetic fatty rats. J Nutr 137:2680-2685
67. Wu G, Bazer FW, Cudd TA et al (2007b) Pharmacokinetics and safety of arginine supplementation in animals. J Nutr 137:1673S-1680S
68. Wu G, Bazer FW, Davis TA et al (2009) Arginine metabolism and nutrition in growth, health and disease. Amino Acids 37:153-168
69. Wu X, Ruan Z, Gao YL et al (2010) Dietary supplementation with l-arginine or N-carbamylglutamate enhances intestinal growth and heat shock protein-70 expression in weanling pigs fed a corn- and soybean meal-based diet. Amino Acids 39:831-839
70. Wu G, Bazer FW, Johnson GA et al (2011a) Important roles for l-glutamine in swine nutrition and production. J Anim Sci 89:2017-2030
71. Wu G, Bazer FW, Burghardt RC et al (2011b) Proline and hydroxyproline metabolism: implications for animal and human nutrition. Amino Acids 40:1053-1063
72. Wu X, Yin YL, Liu YQ et al (2012) Effect of dietary arginine and N-carbamoylglutamate supplementation on reproduction and gene expression of eNOS, VEGFA and PlGF1 in placenta in late pregnancy of sows. Anim Reprod Sci 132:187-192
73. Wu G, Wu ZL, Dai ZL et al (2013a) Dietary requirements of "nutritionally nonessential amino acids" by animals and humans. Amino Acids 44:1107-1113
74. Wu G, Bazer FW, Satterfield MC et al (2013b) Impacts of arginine nutrition on embryonic and fetal development in mammals. Amino Acids 45:241-256
75. Yao K, Guan S, Li T et al (2011) Dietary l-arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets. Br J Nutr 105:703-709
76. Yao K, Yin YL, Li XL et al (2012) Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. Amino Acids 42:2491-2500
77. Yin YL, Tan B et al (2010) Manipulation of dietary nitrogen, amino acids and phosphorus to reduce environmental impact of swine production and enhance animal health. J Food Agric Environ 8:447-462
78. Yin J, Ren W, Liu G et al (2013a) Birth oxidative stress and the development of an antioxidant system in newborn piglets. Free Radic Res 47:1027-1035
79. Yin J, Ren WK, Wu XS et al (2013b) Oxidative stress-mediated signaling pathways: a review. J Food Agric Environ 11:132-139
80. Young JC, Blackwell BA, Apsimon JW et al (1986) Alkaline-degradation of the mycotoxin 4-deoxynivalenol. Tetrahedron Lett 27:1019-1022
81. Yunus AW, Ghareeb K, Abd-El-Fattah AA et al (2011) Gross intestinal adaptations in relation to broiler performance during chronic aflatoxin exposure. Poult Sci 90:1683-1689
82. Zhang J, Yin YL, Shu XG et al (2013a) Oral administration of MSG increases expression of glutamate receptors and transporters in the gastrointestinal tract of young piglets. Amino Acids 45:1169-1177
83. Zhang SH, Qiao SY, Ren M et al (2013b) Supplementation with branched-chain amino acids to a low-protein diet regulates intestinal expression of amino acid and peptide transporters in weanling pigs. Amino Acids 45:1191-1205
84. Zhou XH, Wu X, Yin YL et al (2012) Preventive oral supplementation with glutamine and arginine has beneficial effects on the intestinal mucosa and inflammatory cytokines in endotoxemic rats. Amino Acids 43:813-821