Improving the accuracy of protein stability predictions with multistate design using a variety of backbone ensembles

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 5, 2014, Pages 771-784

  Davey, James A ^a   Chica, Roberto A ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Backrub; Computational protein design; Molecular dynamics; Off target ensemble; On target ensemble; Perturbation and energy minimization; Protein G domain 1; Receiver operating characteristic

Indexed keywords

PROTEIN G; BACTERIAL PROTEIN; IGG FC-BINDING PROTEIN, STREPTOCOCCUS;

ACCURACY; ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY; HYPOTHESIS; IN VITRO STUDY; MOLECULAR DYNAMICS; MOTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; RECEIVER OPERATING CHARACTERISTIC; SIMULATION; STREPTOCOCCUS; TEMPERATURE; BIOLOGY; CHEMISTRY; MOLECULAR GENETICS; PROCEDURES; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; THERMODYNAMICS;

ALGORITHMS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; COMPUTATIONAL BIOLOGY; MOLECULAR SEQUENCE DATA; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; ROC CURVE; STRUCTURAL HOMOLOGY, PROTEIN; THERMODYNAMICS;

EID: 84898046743     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24457     Document Type: Article

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