Deregulated unfolded protein response in chronic wounds of diabetic ob/ob mice: A potential connection to inflammatory and angiogenic disorders in diabetes-impaired wound healing

Biochemical and Biophysical Research Communications

Volumn 446, Issue 1, 2014, Pages 195-200

  Schürmann, Christoph ^a   Goren, Itamar ^a   Linke, Andreas ^a   Pfeilschifter, Josef ^a   Frank, Stefan ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Chronic wounds; Diabetes mellitus; ER stress; Unfolded protein response; Wound healing

Indexed keywords

GAMMA INTERFERON; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDUCIBLE NITRIC OXIDE SYNTHASE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; TUNICAMYCIN; VASCULOTROPIN; X BOX BINDING PROTEIN 1;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHRONIC WOUND; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; FEMALE; IN VITRO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; UNFOLDED PROTEIN RESPONSE; WOUND HEALING IMPAIRMENT;

MUS;

CHRONIC WOUNDS; DIABETES MELLITUS; ER STRESS; UNFOLDED PROTEIN RESPONSE; WOUND HEALING;

ANGIOGENIC PROTEINS; ANIMALS; CELL LINE; CHEMOKINE CXCL2; DIABETES MELLITUS, TYPE 2; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; FEMALE; HEAT-SHOCK PROTEINS; INFLAMMATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; SIGNAL TRANSDUCTION; SKIN; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84898005215     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.02.085     Document Type: Article

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