-
1
-
-
0043022039
-
Regulation, counter-regulation, and immunotherapy of autoimmune responses to immunologically privileged retinal antigens
-
Caspi RR (2003) Regulation, counter-regulation, and immunotherapy of autoimmune responses to immunologically privileged retinal antigens. Immunologic research 27: 149-160.
-
(2003)
Immunologic Research
, vol.27
, pp. 149-160
-
-
Caspi, R.R.1
-
2
-
-
0042430124
-
Immunoregulatory role of ocular macrophages: The macrophages produce RANTES to suppress experimental autoimmune uveitis
-
Sonoda KH, Sasa Y, Qiao H, Tsutsumi C, Hisatomi T, et al. (2003) Immunoregulatory role of ocular macrophages: the macrophages produce RANTES to suppress experimental autoimmune uveitis. J Immunol 171: 2652-2659. (Pubitemid 37025579)
-
(2003)
Journal of Immunology
, vol.171
, Issue.5
, pp. 2652-2659
-
-
Sonoda, K.-H.1
Sasa, Y.2
Qiao, H.3
Tsutsumi, C.4
Hisatomi, T.5
Komiyama, S.6
Kubota, T.7
Sakamoto, T.8
Kawano, Y.-I.9
Ishibashi, T.10
-
3
-
-
34248170725
-
Osteopontin aggravates experimental autoimmune uveoretinitis in mice
-
Kitamura M, Iwabuchi K, Kitaichi N, Kon S, Kitamei H, et al. (2007) Osteopontin aggravates experimental autoimmune uveoretinitis in mice. J Immunol 178: 6567-6572. (Pubitemid 46717440)
-
(2007)
Journal of Immunology
, vol.178
, Issue.10
, pp. 6567-6572
-
-
Kitamura, M.1
Iwabuchi, K.2
Kitaichi, N.3
Kon, S.4
Kitamei, H.5
Mamba, K.6
Yoshida, K.7
Denhardt, D.T.8
Rittling, S.R.9
Ohno, S.10
Uede, T.11
Onoe, K.12
-
4
-
-
61849152990
-
Autoimmunity in the immune privileged eye: Pathogenic and regulatory T cells
-
Caspi R (2008) Autoimmunity in the immune privileged eye: pathogenic and regulatory T cells. Immunologic research 42: 41-50.
-
(2008)
Immunologic Research
, vol.42
, pp. 41-50
-
-
Caspi, R.1
-
5
-
-
31044434001
-
Severe chronic experimental autoimmune uveitis (EAU) of the C57BL/6 mouse induced by adoptive transfer of IRBP1-20-specific T cells
-
DOI 10.1016/j.exer.2005.07.008, PII S0014483505002150
-
Shao H, Liao T, Ke Y, Shi H, Kaplan HJ, et al. (2006) Severe chronic experimental autoimmune uveitis (EAU) of the C57BL/6 mouse induced by adoptive transfer of IRBP1-20-specific T cells. Experimental eye research 82: 323-331. (Pubitemid 43122119)
-
(2006)
Experimental Eye Research
, vol.82
, Issue.2
, pp. 323-331
-
-
Shao, H.1
Liao, T.2
Ke, Y.3
Shi, H.4
Kaplan, H.J.5
Sun, D.6
-
6
-
-
0033579881
-
Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis
-
DOI 10.1084/jem.189.2.219
-
Tarrant TK, Silver PB, Wahlsten JL, Rizzo LV, Chan CC, et al. (1999) Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis. The Journal of experimental medicine 189: 219-230. (Pubitemid 29063244)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.2
, pp. 219-230
-
-
Tarrant, T.K.1
Silver, P.B.2
Wahlsten, J.L.3
Rizzo, L.V.4
Chan, C.-C.5
Wiggert, B.6
Caspi, R.R.7
-
7
-
-
0030587090
-
Genetic Susceptibility to Experimental Autoimmune Uveoretinitis in the Rat Is Associated with an Elevated Th1 Response
-
Caspi RR, Silver PB, Chan CC, Sun B, Agarwal RK, et al. (1996) Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response. Journal of immunology 157: 2668-2675. (Pubitemid 126450484)
-
(1996)
Journal of Immunology
, vol.157
, Issue.6
, pp. 2668-2675
-
-
Caspi, R.R.1
Silver, P.B.2
Chan, C.-C.3
Sun, B.4
Agarwal, R.K.5
Wells, J.6
Oddo, S.7
Fujino, Y.8
Najafian, F.9
Wilder, R.L.10
-
8
-
-
42249084849
-
Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
-
DOI 10.1084/jem.20071258
-
Luger D, Silver PB, Tang J, Cua D, Chen Z, et al. (2008) Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. The Journal of experimental medicine 205: 799-810. (Pubitemid 351549879)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.4
, pp. 799-810
-
-
Luger, D.1
Silver, P.B.2
Tang, J.3
Cua, D.4
Chen, Z.5
Iwakura, Y.6
Bowman, E.P.7
Sgambellone, N.M.8
Chan, C.-C.9
Caspi, R.R.10
-
9
-
-
39049129395
-
Differential roles for IFN-gamma and IL-17 in experimental autoimmune uveoretinitis
-
DOI 10.1093/intimm/dxm135
-
Yoshimura T, Sonoda KH, Miyazaki Y, Iwakura Y, Ishibashi T, et al. (2008) Differential roles for IFN-gamma and IL-17 in experimental autoimmune uveoretinitis. International immunology 20: 209-214. (Pubitemid 351234388)
-
(2008)
International Immunology
, vol.20
, Issue.2
, pp. 209-214
-
-
Yoshimura, T.1
Sonoda, K.-H.2
Miyazaki, Y.3
Iwakura, Y.4
Ishibashi, T.5
Yoshimura, A.6
Yoshida, H.7
-
10
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor
-
Radtke F, Raj K (2003) The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 3: 756-767. (Pubitemid 37328814)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.10
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
11
-
-
0142157141
-
+ T cells
-
DOI 10.1016/S1074-7613(03)00270-X
-
Maekawa Y, Tsukumo S, Chiba S, Hirai H, Hayashi Y, et al. (2003) Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells. Immunity 19: 549-559. (Pubitemid 37311436)
-
(2003)
Immunity
, vol.19
, Issue.4
, pp. 549-559
-
-
Maekawa, Y.1
Tsukumo, S.-I.2
Chiba, S.3
Hirai, H.4
Hayashi, Y.5
Okada, H.6
Kishihara, K.7
Yasutomo, K.8
-
12
-
-
2442522357
-
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
-
DOI 10.1016/S1074-7613(04)00109-8, PII S1074761304001098
-
Tanigaki K, Tsuji M, Yamamoto N, Han H, Tsukada J, et al. (2004) Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity 20: 611-622. (Pubitemid 38638130)
-
(2004)
Immunity
, vol.20
, Issue.5
, pp. 611-622
-
-
Tanigaki, K.1
Tsuji, M.2
Yamamoto, N.3
Han, H.4
Tsukada, J.5
Inoue, H.6
Kubo, M.7
Honjo, T.8
-
13
-
-
2342496710
-
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
-
DOI 10.1016/S0092-8674(04)00451-9, PII S0092867404004519
-
Amsen D, Blander JM, Lee GR, Tanigaki K, Honjo T, et al. (2004) Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 117: 515-526. (Pubitemid 38610236)
-
(2004)
Cell
, vol.117
, Issue.4
, pp. 515-526
-
-
Amsen, D.1
Blander, J.M.2
Lee, G.R.3
Tanigaki, K.4
Honjo, T.5
Flavell, R.A.6
-
14
-
-
33745081482
-
The Interleukin-4 Enhancer CNS-2 Is Regulated by Notch Signals and Controls Initial Expression in NKT Cells and Memory-Type CD4 T Cells
-
DOI 10.1016/j.immuni.2006.04.009, PII S1074761306002676
-
Tanaka S, Tsukada J, Suzuki W, Hayashi K, Tanigaki K, et al. (2006) The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Immunity 24: 689-701. (Pubitemid 43884897)
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 689-701
-
-
Tanaka, S.1
Tsukada, J.2
Suzuki, W.3
Hayashi, K.4
Tanigaki, K.5
Tsuji, M.6
Inoue, H.7
Honjo, T.8
Kubo, M.9
-
15
-
-
84880729295
-
Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals
-
Bailis W, Yashiro-Ohtani Y, Fang TC, Hatton RD, Weaver CT, et al. (2013) Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. Immunity 39: 148-159.
-
(2013)
Immunity
, vol.39
, pp. 148-159
-
-
Bailis, W.1
Yashiro-Ohtani, Y.2
Fang, T.C.3
Hatton, R.D.4
Weaver, C.T.5
-
16
-
-
22144492615
-
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
-
DOI 10.1038/ni1209
-
Minter LM, Turley DM, Das P, Shin HM, Joshi I, et al. (2005) Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nature immunology 6: 680-688. (Pubitemid 41716741)
-
(2005)
Nature Immunology
, vol.6
, Issue.7
, pp. 680-688
-
-
Minter, L.M.1
Turley, D.M.2
Das, P.3
Shin, H.M.4
Joshi, I.5
Lawlor, R.G.6
Cho, O.H.7
Palaga, T.8
Gottipati, S.9
Telfer, J.C.10
Kostura, L.11
Fauq, A.H.12
Simpson, K.13
Such, K.A.14
Miele, L.15
Golde, T.E.16
Miller, S.D.17
Osborne, B.A.18
-
17
-
-
80052655552
-
Delta-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis
-
Reynolds ND, Lukacs NW, Long N, Karpus WJ (2011) Delta-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis. Journal of immunology 187: 2803-2813.
-
(2011)
Journal of Immunology
, vol.187
, pp. 2803-2813
-
-
Reynolds, N.D.1
Lukacs, N.W.2
Long, N.3
Karpus, W.J.4
-
18
-
-
80052685578
-
Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development
-
Bassil R, Zhu B, Lahoud Y, Riella LV, Yagita H, et al. (2011) Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development. Journal of immunology 187: 2322-2328.
-
(2011)
Journal of Immunology
, vol.187
, pp. 2322-2328
-
-
Bassil, R.1
Zhu, B.2
Lahoud, Y.3
Riella, L.V.4
Yagita, H.5
-
19
-
-
84855384313
-
Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody
-
Ishida W, Fukuda K, Sakamoto S, Koyama N, Koyanagi A, et al. (2011) Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody. Investigative ophthalmology & visual science 52: 8224-8230.
-
(2011)
Investigative Ophthalmology & Visual Science
, vol.52
, pp. 8224-8230
-
-
Ishida, W.1
Fukuda, K.2
Sakamoto, S.3
Koyama, N.4
Koyanagi, A.5
-
20
-
-
52549130987
-
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
-
Maekawa Y, Minato Y, Ishifune C, Kurihara T, Kitamura A, et al. (2008) Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nature immunology 9: 1140-1147.
-
(2008)
Nature Immunology
, vol.9
, pp. 1140-1147
-
-
Maekawa, Y.1
Minato, Y.2
Ishifune, C.3
Kurihara, T.4
Kitamura, A.5
-
21
-
-
1542317449
-
Notch regulation of lymphocyte development and function
-
DOI 10.1038/ni1045
-
Radtke F, Wilson A, Mancini SJ, MacDonald HR (2004) Notch regulation of lymphocyte development and function. Nature immunology 5: 247-253. (Pubitemid 38332121)
-
(2004)
Nature Immunology
, vol.5
, Issue.3
, pp. 247-253
-
-
Radtke, F.1
Wilson, A.2
Mancini, S.J.C.3
MacDonald, H.R.4
-
22
-
-
34250005444
-
H17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
-
DOI 10.1038/nm1585, PII NM1585
-
Amadi-Obi A, Yu CR, Liu X, Mahdi RM, Clarke GL, et al. (2007) TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1. Nat Med 13: 711-718. (Pubitemid 46889754)
-
(2007)
Nature Medicine
, vol.13
, Issue.6
, pp. 711-718
-
-
Amadi-Obi, A.1
Yu, C.-R.2
Liu, X.3
Mahdi, R.M.4
Clarke, G.L.5
Nussenblatt, R.B.6
Gery, I.7
Lee, Y.S.8
Egwuagu, C.E.9
-
23
-
-
77950534839
-
Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor
-
Alam MS, Maekawa Y, Kitamura A, Tanigaki K, Yoshimoto T, et al. (2010) Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor. Proc Natl Acad Sci U S A 107: 5943-5948.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5943-5948
-
-
Alam, M.S.1
Maekawa, Y.2
Kitamura, A.3
Tanigaki, K.4
Yoshimoto, T.5
-
24
-
-
0027160394
-
Effects of CD8 depletion on retinal soluble antigen induced experimental autoimmune uveoretinitis
-
Calder VL, Zhao ZS, Wang Y, Barton K, Lightman SL (1993) Effects of CD8 depletion on retinal soluble antigen induced experimental autoimmune uveoretinitis. Immunology 79: 255-262. (Pubitemid 23172221)
-
(1993)
Immunology
, vol.79
, Issue.2
, pp. 255-262
-
-
Calder, V.L.1
Zhao, Z.S.2
Wang, Y.3
Barton, K.4
Lightman, S.L.5
-
25
-
-
54949142477
-
Cytokine-mediated regulation of antimicrobial proteins
-
Kolls JK, McCray PB Jr, Chan YR (2008) Cytokine-mediated regulation of antimicrobial proteins. Nat Rev Immunol 8: 829-835.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 829-835
-
-
Kolls, J.K.1
McCray Jr., P.B.2
Chan, Y.R.3
-
26
-
-
35348983341
-
Interleukin-22 but Not Interleukin-17 Provides Protection to Hepatocytes during Acute Liver Inflammation
-
DOI 10.1016/j.immuni.2007.07.023, PII S1074761307004426
-
Zenewicz LA, Yancopoulos GD, Valenzuela DM, Murphy AJ, Karow M, et al. (2007) Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity 27: 647-659. (Pubitemid 47615503)
-
(2007)
Immunity
, vol.27
, Issue.4
, pp. 647-659
-
-
Zenewicz, L.A.1
Yancopoulos, G.D.2
Valenzuela, D.M.3
Murphy, A.J.4
Karow, M.5
Flavell, R.A.6
-
27
-
-
38849187386
-
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation
-
DOI 10.1172/JCI33263
-
Ma HL, Liang S, Li J, Napierata L, Brown T, et al. (2008) IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. The Journal of clinical investigation 118: 597-607. (Pubitemid 351206549)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 597-607
-
-
Ma, H.-L.1
Liang, S.2
Li, J.3
Napierata, L.4
Brown, T.5
Benoit, S.6
Senices, M.7
Gill, D.8
Dunussi-Joannopoulos, K.9
Collins, M.10
Nickerson-Nutter, C.11
Fouser, L.A.12
Young, D.A.13
-
28
-
-
72849131815
-
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
-
Eyerich S, Eyerich K, Pennino D, Carbone T, Nasorri F, et al. (2009) Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. The Journal of clinical investigation 119: 3573-3585.
-
(2009)
The Journal of Clinical Investigation
, vol.119
, pp. 3573-3585
-
-
Eyerich, S.1
Eyerich, K.2
Pennino, D.3
Carbone, T.4
Nasorri, F.5
-
29
-
-
80052675874
-
IL-22-induced regulatory CD11b+ APCs suppress experimental autoimmune uveitis
-
Ke Y, Sun D, Jiang G, Kaplan HJ, Shao H (2011) IL-22-induced regulatory CD11b+ APCs suppress experimental autoimmune uveitis. Journal of immunology 187: 2130-2139.
-
(2011)
Journal of Immunology
, vol.187
, pp. 2130-2139
-
-
Ke, Y.1
Sun, D.2
Jiang, G.3
Kaplan, H.J.4
Shao, H.5
-
30
-
-
61349119917
-
RBP-Jkappa binds to and represses transcription of the p53 tumor suppressor gene
-
Boggs K, Henderson B, Reisman D (2009) RBP-Jkappa binds to and represses transcription of the p53 tumor suppressor gene. Cell Biol Int 33: 318-324.
-
(2009)
Cell Biol Int
, vol.33
, pp. 318-324
-
-
Boggs, K.1
Henderson, B.2
Reisman, D.3
-
31
-
-
84885629579
-
Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKalpha/IKKbeta
-
Jin S, Mutvei AP, Chivukula IV, Andersson ER, Ramskold D, et al. (2013) Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKalpha/IKKbeta. Oncogene 32: 4892-4902.
-
(2013)
Oncogene
, vol.32
, pp. 4892-4902
-
-
Jin, S.1
Mutvei, A.P.2
Chivukula, I.V.3
Andersson, E.R.4
Ramskold, D.5
|