Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ

Oncogene

Volumn 32, Issue 41, 2013, Pages 4892-4902

  Jin, S ^a   Mutvei, A P ^a   Chivukula, I V ^a   Andersson, E R ^a   Ramskold D ^a,b   Sandberg, R ^a,b   Lee, K L ^c   Kronqvist, P ^d   Mamaeva, V ^d   Ostling P ^e   Mpindi, J P ^e   Kallioniemi, O ^e   Screpanti, I ^f   Poellinger, L ^a,c   Sahlgren, C ^d   Lendahl, U ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY OF TURKU   (Finland)

^e UNIVERSITY OF HELSINKI   (Finland)

^f SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

BCL; breast cancer; Cytokine; estrogen receptor; inflammation; tumor stroma

Indexed keywords

DNA BINDING PROTEIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; JANUS KINASE; LIPOPOLYSACCHARIDE; NOTCH RECEPTOR; PROTEIN CSL; PROTEIN P53; STAT PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST TUMOR; CELL INTERACTION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN TISSUE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR CELL; UPREGULATION;

AUTOCRINE COMMUNICATION; BREAST NEOPLASMS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; I-KAPPA B KINASE; INTERLEUKIN-6; JANUS KINASES; MACROPHAGES; PARACRINE COMMUNICATION; RECEPTORS, NOTCH; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84885629579     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.517     Document Type: Article

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