Immunoregulatory role of ocular macrophages: The macrophages produce RANTES to suppress experimental autoimmune uveitis

Journal of Immunology

Volumn 171, Issue 5, 2003, Pages 2652-2659

  Sonoda, Koh Hei ^a   Sasa, Yukio ^a   Qiao, Hong ^a   Tsutsumi, Chikako ^a   Hisatomi, Toshio ^a   Komiyama, Sohtaro ^a   Kubota, Toshiaki ^a   Sakamoto, Taiji ^b   Kawano, Yoh Ichi ^c   Ishibashi, Tatsuro ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c HAMANOMACHI HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; MESSENGER RNA; NEUTRALIZING ANTIBODY; RANTES;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; IMMUNOREGULATION; LYMPHOCYTE COUNT; MACROPHAGE; MESSENGER RNA SYNTHESIS; MOUSE; NONHUMAN; OPHTHALMOSCOPY; PATHOGENESIS; RETINA DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; T LYMPHOCYTE; TISSUE INJURY; UVEITIS;

EID: 0042430124     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.5.2652     Document Type: Article

References (47)

1. Gery, I., M. Mochizuki, and R. B. Nussenblatt. 1986. Retinal specific antigens and immunopathogenic process they provoke. Prog. Retinal. Res. 5:75.
2. Forrester, J. V. 1991. Uveitis: pathogenesis. Lancet 338:1498.
3. Forrester, J. V. 1990. Endogenous posterior uveitis. Br. J. Ophthalmol. 74:620.
4. Dijkstra, C. D., E. A. Dopp, I. M. Vogels, and C. J. Van Noorden. 1987. Macrophages and dendritic cells in antigen-induced arthritis: an immunohistochemical study using cryostat sections of the whole knee joint of rat. Scand. J. Immunol. 26:513.
5. Noble, B., K. Ren, J. Taverne, J. Dipirro, J. Van Liew, C. Dijkstra, G. Janossy, and L. W. Poulter. 1990. Mononuclear cells in glomeruli and cytokines in urine reflect the severity of experimental proliferative immune complex glomerulonephritis. Clin. Exp. Immunol. 80:281.
6. Cohen, S. B., C. D. Dijkstra, and A. P. Weetman. 1988. Sequential analysis of experimental autoimmune thyroiditis induced by neonatal thymectomy in the Buffalo strain rat. Cell. Immunol. 114:126.
7. Godiska, R., D. Chantry, G. N. Dietsch, and P. W. Gray. 1995. Chemokine expression in murine experimental allergic encephalomyelitis. J. Neuroimmunol. 58:167.
8. Butler, T. L., and P. G. McMenamin. 1996. Resident and infiltrating immune cells in the uveal tract in the early and late stages of experimental autoimmune uveoretinitis. Invest. Ophthalmol. Vis. Sci. 37:2195.
9. Dick, A. D., P. G. McMenamin, H. Korner, B. J. Scallon, J. Ghrayeb, J. V. Forrester, and J. D. Sedgwick. 1996. Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina. Eur. J. Immunol. 26:1018.
10. Jiang, H. R., L. Lumsden, and J. V. Forrester. 1999. Macrophages and dendritic cells in IRBP-induced experimental autoimmune uveoretinitis in B10RIII mice. Invest. Ophthalmol. Vis. Sci. 40:3177.
11. Pouvreau, I., J. C. Zech, B. Thillaye-Goldenberg, M. C. Naud, N. Van Rooijen, and Y. de Kozak. 1998. Effect of macrophage depletion by liposomes containing dichloromethylene-diphosphonate on endotoxin-induced uveitis. J. Neuroimmunol. 86:171.
12. Forrester, J. V., I. Huitinga, L. Lumsden, and C. D. Dijkstra. 1998. Marrow-derived activated macrophages are required during the effector phase of experimental autoimmune uveoretinitis in rats. Curr. Eye Res. 17:426.
13. Dick, A. D., B., Kreutzer, B. Laliotou, and J. V. Forrester. 1997. Phenotypic analysis of retinal leukocyte infiltration during combined cyclosporin A and nasal antigen administration of retinal antigens: delay and inhibition of macrophage and granulocyte infiltration. Ocul. Immunol. Inflamm. 5:129.
14. van den Berg, T. K., J. J. Breve, J. G. Damoiseaux, E. A. Dopp, S. Kelm, P. R. Crocker, C. D. Dijkstra, and G. Kraal. 1992. Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule. J. Exp. Med. 176:647.
15. Cua, D. J., D. R. Hinton, L. Kirkman, and S. A. Stohlman. 1995. Macrophages regulate induction of delayed-type hypersensitivity and experimental allergic encephalomyelitis in SJL mice. Eur. J. Immunol. 25:2318.
16. Verma, M. J., A. Lloyd, H. Rager, R. Strieter, S. Kunkel, D. Taub, and D. Wakefield. 1997. Chemokines in acute anterior uveitis. Curr. Eye Res. 16:1202.
17. Karpus, W. J., and K. J. Kennedy. 1997. MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation. J. Leukocyte Biol. 62:681.
18. Karpus, W. J., and R. M. Ransohoff. 1998. Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis. J. Immunol. 161:2667.
19. + T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions. Proc. Natl. Acad. Sci. USA 96:6873.
20. McManus, C., J. W. Berman, F. M. Brett, H. Staunton, M. Farrell, and C. F. Brosnan. 1998. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study. J. Neuroimmunol. 86:20.
21. Sorensen, T. L., M. Tani, J. Jensen, V. Pierce, C. Lucchinetti, V. A. Folcik, S. Qin, J. Rottman, F. Sellebjerg, R. M. Strieter, et al. 1999. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J. Clin. Invest. 103:807.
22. Appay, V., and S. L. Rowland-Jones. 2001. RANTES: a versatile and controversial chemokine. Trends Immunol. 22:83.
23. Zlotnik, A., and O. Yoshie. 2000. Chemokines: a new classification system and their role in immunity. Immunity 12:121.
24. Meurer, R., G. Van Riper, W. Feeney, P. Cunningham, D. Hora, Jr., M. S. Springer, D. E. MacIntyre, and H. Rosen. 1993. Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1α, or human interleukin 8. J. Exp. Med. 178:1913.
25. Avichezer, D., C. C. Chan, P. B. Silver, B. Wiggert, and R. R. Caspi. 2000. Residues 1-20 of IRBP and whole IRBP elicit different uveitogenic and immunological responses in interferon gamma deficient mice. Exp. Eye Res. 71:111.
26. Avichezer, D., P. B. Silver, C. C. Chan, B. Wiggert, and R. R. Caspi. 2000. Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype. Invest. Ophthalmol. Vis. Sci. 41:127.
27. Thurau, S. R., C. C. Chan, R. B. Nussenblatt, and R. R. Caspi. 1997. Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animals. Clin. Exp. Immunol. 109:370.
28. Caspi, R. R., F. G. Roberge, C. C. Chan, B. Wiggert, G. J. Chader, L. A. Rozenszajn, Z. Lando, and R. B. Nussenblatt. 1988. A new model of autoimmune disease: experimental autoimmune uveoretinitis induced in mice with two different retinal antigens. J. Immunol. 140:1490.
29. Sonoda, K. H., T. Sakamoto, H. Yoshikawa, S. Ashizuka, Y. Ohshima, K. Kishihara, K. Nomoto, T. Ishibashi, and H. Inomata. 1998. Inhibition of corneal inflammation by the topical use of Ras farnesyltransferase inhibitors: selective inhibition of macrophage localization. Invest. Ophthalmol. Vis. Sci. 39:2245.
30. Iarlori, C., M. Reale, A. Lugaresi, G. De Luca, L. Bonanni, A. Di Iorio, C. Feliciani, P. Conti, and D. Gambi. 2000. RANTES production and expression is reduced in relapsing-remitting multiple sclerosis patients treated with interferon-β-1b. J. NeuroImmunol. 107:100.
31. + T cell line and clone that induce experimental autoimmune uveoretinitis in B10.A mice. J. Immunol. 156:1654.
32. Caspi, R. R., B. Sun, R. K. Agarwal, P. B. Silver, L. V. Rizzo, C. C. Chan, B. Wiggert, and R. L. Wilder. 1997. T cell mechanisms in experimental autoimmune uveoretinitis: susceptibility is a function of the cytokine response profile. Eye 11:209.
33. Laliotou, B., and A. D. Dick. 1999. Modulating phenotype and cytokine production of leucocytic retinal infiltrate in experimental autoimmune uveoretinitis following intranasal tolerance induction with retinal antigens. Br. J. Ophthalmol. 83:478.
34. Robertson, M. J., L. P. Erwig, J. Liversidge, J. V. Forrester, A. J. Rees, and A. D. Dick. 2002. Retinal microenvironment controls resident and infiltrating macrophage function during uveoretinitis. Invest. Ophthalmol. Vis. Sci. 43:2250.
35. Backman, C., P. T. Biddle, T. Ebendal, P. M. Friden, G. A. Gerhardt, M. A. Henry, L. Mackerlova, S. Soderstrom, I. Stromberg, L. Walus, et al. 1995. Effects of transferrin receptor antibody-NGF conjugate on young and aged septal transplants in oculo. Exp. Neurol. 132:1.
36. Viti, F., L. Giovannoni, and D. Neri. 2002. Recombinant antibodies for the selective targeting of tumor neovasculature. Curr. Opin. Drug Discov. Dev. 5:204.
37. Namba, K., K. Ogasawara, N. Kitaichi, N. Matsuki, A. Takahashi, Y. Sasamoto, S. Kotake, H. Matsuda, K. Iwabuchi, S. Ohno, et al. 1998. Identification of a peptide inducing experimental autoimmune uveoretinitis (EAU) in H-2Ak-carrying mice. Clin. Exp. Immunol. 111:442.
38. Mack, M., J. Cihak, C. Simonis, B. Luckow, A. E. Proudfoot, J. Plachy, H. Bruhl, M. Frink, H. J. Anders, V. Vielhauer, et al. 2001. Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. J. Immunol. 166:4697.
39. + T cells to the spleen during the generation of regulatory T cells in tolerance. J. Immunol. 169:31.
40. Sakaguchi, S. 2000. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101:455.
41. Hong, S., M. T. Wilson, I. Serizawa, L. Wu, N. Singh, O. V. Naidenko, T. Miura, T. Haba, D. C. Scherer, J. Wei, et al. 2001. The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat. Med. 7:1052.
42. Moodycliffe, A. M., D. Nghiem, G. Clydesdale, and S. E. Ullrich. 2000. Immune suppression and skin cancer development: regulation by NKT cells. Nat. Immunol. 1:521.
43. Born, W., C. Cady, J. Jones-Carson, A. Mukasa, M. Lahn, and R. O'Brien. 1999. Immunoregulatory functions of gamma delta T cells. Adv. Immunol. 71:77.
44. Hayday, A., and L. Geng. 1997. γδ cells regulate autoimmunity. Curr. Opin. Immunol. 9:884.
45. Avichezer, D., C. C. Chan, P. B. Silver, B. Wiggert, and R. R. Caspi. 2000. Residues 1-20 of IRBP and whole IRBP elicit different uveitogenic and immunological responses in interferon gamma deficient mice. Exp. Eye Res. 71:111.
46. Adamus, G., M. Manczak, and M. Machnicki. 2001. Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE. Invest. Ophthalmol. Vis. Sci. 42:2894.
47. Crane, I. J., S. McKillop-Smith, C. A. Wallace, G. R. Lamont, and J. V. Forrester. 2001. Expression of the chemokines MIP-1alpha, MCP-1, and RANTES in experimental autoimmune uveitis. Invest. Ophthalmol. Vis. Sci. 42:1547.