How a low-fidelity DNA polymerase chooses non-watson-crick from watson-crick incorporation

Journal of the American Chemical Society

Volumn 136, Issue 13, 2014, Pages 4927-4937

  Wu, Wen Jin ^a   Su, Mei I ^a,b   Wu, Jian Li ^a   Kumar, Sandeep ^c   Lim, Liang Hin ^a,d   Wang, Chun Wei Eric ^a,d   Nelissen, Frank H T ^d   Chen, Ming Chuan Chad ^a   Doreleijers, Jurgen F ^f   Wijmenga, Sybren S ^e   Tsai, Ming Daw ^a,b,c,d  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c OHIO STATE UNIVERSITY   (United States)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CATALYSIS; POLYMERS; REPAIR; VIRUSES;

AFRICAN SWINE FEVER VIRUS; CONFORMATIONAL CHANGE; DNA POLYMERASE; DNA-BINDING MODES; ENZYME BINDS; SOLUTION STRUCTURES; TERNARY COMPLEX; WATSON-CRICK BASE PAIRING;

DNA;

DNA POLYMERASE; 2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE; DEOXYCYTIDINE PHOSPHATE; DEOXYGUANOSINE PHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DNA; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE X; GUANOSINE TRIPHOSPHATE;

ALPHA HELIX; ARTICLE; BASE PAIRING; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENZYME STRUCTURE; GENE MUTATION; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; PROTEIN DNA BINDING; WATSON CRICK BASE PAIRING; AFRICAN SWINE FEVER; AFRICAN SWINE FEVER VIRUS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PIG; PROTEIN CONFORMATION; VIROLOGY;

AFRICAN SWINE FEVER; AFRICAN SWINE FEVER VIRUS; ANIMALS; BASE PAIRING; DEOXYCYTOSINE NUCLEOTIDES; DEOXYGUANINE NUCLEOTIDES; DNA; DNA POLYMERASE BETA; DNA-DIRECTED DNA POLYMERASE; GUANOSINE TRIPHOSPHATE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; SWINE;

EID: 84897562638     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4102375     Document Type: Article

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