Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of intracellular calcium and Akt/β-catenin pathway

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Wang, Hua ^a   Sun, Wen ^a   Ma, Junqing ^a   Pan, Yongchu ^a   Wang, Lin ^a   Zhang, Weibing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; POLYCYSTIN 1; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; WNT PROTEIN; CALCIUM; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIN;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPIGENETICS; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; STRESS STRAIN RELATIONSHIP; TISSUE REGENERATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOMECHANICS; CELL LINE; CELL NUCLEUS; CYTOLOGY; DEFICIENCY; GENE EXPRESSION; GENE SILENCING; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; RNA INTERFERENCE;

ANIMALS; BETA CATENIN; BIOMECHANICAL PHENOMENA; CALCIUM; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; MICE; OSTEOBLASTS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRPP CATION CHANNELS;

EID: 84897541931     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091730     Document Type: Article

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