Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca2+- and ATP-dependent in MC3T3-E1 osteoblasts

Bone

Volumn 42, Issue 4, 2008, Pages 644-652

  Liu, Dawei ^a,d   Genetos, Damian C ^b   Shao, Ying ^c   Geist, Derik J ^d   Li, Jiliang ^d,e   Ke, Hua Zhu ^f   Turner, Charles H ^d   Duncan, Randall L ^c,d  

^a MARQUETTE UNIVERSITY SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e INDIANA UNIVERSITY   (United States)

^f PFIZER INC   (United States)

Author keywords

ATP; Calcium channel; Fluid shear stress; Osteoblast; Purinergic

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ADENOSINE TRIPHOSPHATE; CALCIUM; CALCIUM CHANNEL L TYPE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; PURINERGIC RECEPTOR; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BONE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ISOLATION; CHELATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HYDROLYSIS; KNOCKOUT MOUSE; MECHANOTRANSDUCTION; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; SHEAR STRESS; STATISTICAL SIGNIFICANCE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELL LINE; CULTURE MEDIA, CONDITIONED; ENZYME ACTIVATION; ION CHANNELS; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OSTEOBLASTS; OSTEOPONTIN; PHOSPHOINOSITIDE PHOSPHOLIPASE C; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, PURINERGIC;

EID: 40849111180     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2007.09.058     Document Type: Article

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