메뉴 건너뛰기




Volumn 44, Issue 6, 2009, Pages 1121-1133

The polycystic kidney disease 1 (Pkd1) gene is required for the responses of osteochondroprogenitor cells to midpalatal suture expansion in mice

Author keywords

Chondrocyte; Mechanical force; Osteoblast; Polycystin 1; Suture

Indexed keywords

POLYCYSTIN 1; TRANSCRIPTION FACTOR RUNX2;

EID: 67349153122     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.02.018     Document Type: Article
Times cited : (38)

References (58)
  • 1
    • 0031770558 scopus 로고    scopus 로고
    • Mechanotransduction and functional response of the skeleton to physical stress: the mechanisms and mechanics of bone adaptation
    • Turner C.H., and Pavalko F.M. Mechanotransduction and functional response of the skeleton to physical stress: the mechanisms and mechanics of bone adaptation. J. Orthop Sci. 3 6 (1998) 346-355
    • (1998) J. Orthop Sci. , vol.3 , Issue.6 , pp. 346-355
    • Turner, C.H.1    Pavalko, F.M.2
  • 2
    • 0033991383 scopus 로고    scopus 로고
    • Toward a unifying theory of bone remodeling
    • Martin R.B. Toward a unifying theory of bone remodeling. Bone. 26 1 (2000) 1-6
    • (2000) Bone. , vol.26 , Issue.1 , pp. 1-6
    • Martin, R.B.1
  • 3
    • 23844535859 scopus 로고    scopus 로고
    • Mechanisms by which exercise improves bone strength
    • Turner C.H., and Robling A.G. Mechanisms by which exercise improves bone strength. J. Bone Miner. Metab. 23 Suppl (2005) 16-22
    • (2005) J. Bone Miner. Metab. , vol.23 SUPPL , pp. 16-22
    • Turner, C.H.1    Robling, A.G.2
  • 4
    • 34548319400 scopus 로고    scopus 로고
    • Mechanical loading by fluid shear stress enhances IGF-1 receptor signaling in osteoblasts in a PKCzeta-dependent manner
    • Triplett J.W., O'Riley R., Tekulve K., Norvell S.M., and Pavalko F.M. Mechanical loading by fluid shear stress enhances IGF-1 receptor signaling in osteoblasts in a PKCzeta-dependent manner. Mol. Cell. Biomech. 4 1 (2007) 13-25
    • (2007) Mol. Cell. Biomech. , vol.4 , Issue.1 , pp. 13-25
    • Triplett, J.W.1    O'Riley, R.2    Tekulve, K.3    Norvell, S.M.4    Pavalko, F.M.5
  • 6
    • 3142762332 scopus 로고    scopus 로고
    • Shear stress inhibits while disuse promotes osteocyte apoptosis
    • Bakker A., Klein-Nulend J., and Burger E. Shear stress inhibits while disuse promotes osteocyte apoptosis. Biochem. Biophys. Res. Commun. 320 4 (2004) 1163-1168
    • (2004) Biochem. Biophys. Res. Commun. , vol.320 , Issue.4 , pp. 1163-1168
    • Bakker, A.1    Klein-Nulend, J.2    Burger, E.3
  • 7
    • 37449027378 scopus 로고    scopus 로고
    • Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading
    • You L., Temiyasathit S., Lee P., Kim C.H., Tummala P., Yao W., et al. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone. 42 1 (2008) 172-179
    • (2008) Bone. , vol.42 , Issue.1 , pp. 172-179
    • You, L.1    Temiyasathit, S.2    Lee, P.3    Kim, C.H.4    Tummala, P.5    Yao, W.6
  • 8
    • 34248566783 scopus 로고    scopus 로고
    • Mechanical force-induced midpalatal suture remodeling in mice
    • Hou B., Fukai N., and Olsen B.R. Mechanical force-induced midpalatal suture remodeling in mice. Bone 40 6 (2007) 1483-1493
    • (2007) Bone , vol.40 , Issue.6 , pp. 1483-1493
    • Hou, B.1    Fukai, N.2    Olsen, B.R.3
  • 9
    • 0029069583 scopus 로고
    • The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
    • Hughes J., Ward C.J., Peral B., Aspinwall R., Clark K., San Millán J.L., et al. The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains. Nat. Genet. 10 2 (1995) 151-160
    • (1995) Nat. Genet. , vol.10 , Issue.2 , pp. 151-160
    • Hughes, J.1    Ward, C.J.2    Peral, B.3    Aspinwall, R.4    Clark, K.5    San Millán, J.L.6
  • 10
    • 0030909957 scopus 로고    scopus 로고
    • PKD1 interacts with PKD2 through a probable coiled-coil domain
    • Qian F., Germino F.J., Cai Y., Zhang X., Somlo S., and Germino G.G. PKD1 interacts with PKD2 through a probable coiled-coil domain. Nat. Genet. 16 2 (1997 Jun) 179-183
    • (1997) Nat. Genet. , vol.16 , Issue.2 , pp. 179-183
    • Qian, F.1    Germino, F.J.2    Cai, Y.3    Zhang, X.4    Somlo, S.5    Germino, G.G.6
  • 11
    • 9844245128 scopus 로고    scopus 로고
    • Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains
    • Sandford R., Sgotto B., Aparicio S., Brenner S., Vaudin M., Wilson R.K., et al. Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains. Hum. Mol. Genet. 6 9 (1997) 1483-1489
    • (1997) Hum. Mol. Genet. , vol.6 , Issue.9 , pp. 1483-1489
    • Sandford, R.1    Sgotto, B.2    Aparicio, S.3    Brenner, S.4    Vaudin, M.5    Wilson, R.K.6
  • 13
    • 34948834648 scopus 로고    scopus 로고
    • Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell-cell mechanical adhesion
    • Boca M., D'Amato L., Distefano G., Polishchuk R.S., Germino G.G., and Boletta A. Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell-cell mechanical adhesion. Mol. Biol. Cell 18 10 (2007) 4050-4061
    • (2007) Mol. Biol. Cell , vol.18 , Issue.10 , pp. 4050-4061
    • Boca, M.1    D'Amato, L.2    Distefano, G.3    Polishchuk, R.S.4    Germino, G.G.5    Boletta, A.6
  • 14
    • 0037317302 scopus 로고    scopus 로고
    • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
    • Nauli S.M., Alenghat F.J., Luo Y., Williams E., Vassilev P., Li X., et al. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat. Genet. 33 2 (2003) 129-137
    • (2003) Nat. Genet. , vol.33 , Issue.2 , pp. 129-137
    • Nauli, S.M.1    Alenghat, F.J.2    Luo, Y.3    Williams, E.4    Vassilev, P.5    Li, X.6
  • 15
    • 0032955309 scopus 로고    scopus 로고
    • Murine Pkd1 is a developmentally regulated gene from morula to adulthood: role in tissue condensation and patterning
    • Guillaume R., D'Agati V., Daoust M., and Trudel M. Murine Pkd1 is a developmentally regulated gene from morula to adulthood: role in tissue condensation and patterning. Dev. Dyn. 214 4 (1999) 337-348
    • (1999) Dev. Dyn. , vol.214 , Issue.4 , pp. 337-348
    • Guillaume, R.1    D'Agati, V.2    Daoust, M.3    Trudel, M.4
  • 16
    • 33750067366 scopus 로고    scopus 로고
    • Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression
    • Xiao Z., Zhang S., Mahlios J., Zhou G., Magenheimer B.S., Guo D., et al. Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression. J. Biol. Chem. 281 41 (2006) 30884-30895
    • (2006) J. Biol. Chem. , vol.281 , Issue.41 , pp. 30884-30895
    • Xiao, Z.1    Zhang, S.2    Mahlios, J.3    Zhou, G.4    Magenheimer, B.S.5    Guo, D.6
  • 17
    • 0035834136 scopus 로고    scopus 로고
    • Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
    • Boulter C., Mulroy S., Webb S., Fleming S., Brindle K., and Sandford R. Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene. Proc. Natl. Acad. Sci. U. S. A. 98 21 (2001) 12174-12179
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.21 , pp. 12174-12179
    • Boulter, C.1    Mulroy, S.2    Webb, S.3    Fleming, S.4    Brindle, K.5    Sandford, R.6
  • 18
    • 0035504102 scopus 로고    scopus 로고
    • Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects
    • Lu W., Shen X., Pavlova A., Lakkis M., Ward C.J., Pritchard L., et al. Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects. Hum. Mol. Genet. 10 21 (2001) 2385-2396
    • (2001) Hum. Mol. Genet. , vol.10 , Issue.21 , pp. 2385-2396
    • Lu, W.1    Shen, X.2    Pavlova, A.3    Lakkis, M.4    Ward, C.J.5    Pritchard, L.6
  • 19
    • 44449137071 scopus 로고    scopus 로고
    • A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5′ end of Pkd1
    • Starremans P.G., Li X., Finnerty P.E., Guo L., Takakura A., Neilson E.G., et al. A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5′ end of Pkd1. Kidney Int. 73 12 (2008) 1394-1405
    • (2008) Kidney Int. , vol.73 , Issue.12 , pp. 1394-1405
    • Starremans, P.G.1    Li, X.2    Finnerty, P.E.3    Guo, L.4    Takakura, A.5    Neilson, E.G.6
  • 20
    • 34250801612 scopus 로고    scopus 로고
    • Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone
    • Maeda Y., Nakamura E., Nguyen M.T., Suva L.J., Swain F.L., Razzaque M.S., et al. Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone. Proc. Natl. Acad. Sci. U. S. A. 104 15 (2007) 6382-6387
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.15 , pp. 6382-6387
    • Maeda, Y.1    Nakamura, E.2    Nguyen, M.T.3    Suva, L.J.4    Swain, F.L.5    Razzaque, M.S.6
  • 21
    • 29344461912 scopus 로고    scopus 로고
    • Nell-1 induced bone formation within the distracted intermaxillary suture
    • Cowan C.M., Cheng S., Ting K., Soo C., Walder B., Wu B., et al. Nell-1 induced bone formation within the distracted intermaxillary suture. Bone 38 1 (2006) 48-58
    • (2006) Bone , vol.38 , Issue.1 , pp. 48-58
    • Cowan, C.M.1    Cheng, S.2    Ting, K.3    Soo, C.4    Walder, B.5    Wu, B.6
  • 22
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 21 1 (1999) 70-71
    • (1999) Nat Genet. , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 23
    • 0038284054 scopus 로고    scopus 로고
    • Study of stress distribution and displacement of various craniofacial structures following application of transverse orthopedic forces-a three-dimensional FEM study
    • Jafari A., Shetty K.S., and Kumar M. Study of stress distribution and displacement of various craniofacial structures following application of transverse orthopedic forces-a three-dimensional FEM study. Angle Orthod. 73 1 (2003) 12-20
    • (2003) Angle Orthod. , vol.73 , Issue.1 , pp. 12-20
    • Jafari, A.1    Shetty, K.S.2    Kumar, M.3
  • 24
    • 0033662265 scopus 로고    scopus 로고
    • Cranial sutures as intramembranous bone growth sites
    • Opperman L.A. Cranial sutures as intramembranous bone growth sites. Dev. Dyn. 219 4 (2000) 472-485
    • (2000) Dev. Dyn. , vol.219 , Issue.4 , pp. 472-485
    • Opperman, L.A.1
  • 25
    • 0036893423 scopus 로고    scopus 로고
    • Mechanobiology of craniofacial sutures
    • Mao J.J. Mechanobiology of craniofacial sutures. J. Dent. Res. 81 12 (2002) 810-816
    • (2002) J. Dent. Res. , vol.81 , Issue.12 , pp. 810-816
    • Mao, J.J.1
  • 26
    • 33645130993 scopus 로고    scopus 로고
    • FGF signalling in craniofacial development and developmental disorders
    • Nie X., Luukko K., and Kettunen P. FGF signalling in craniofacial development and developmental disorders. Oral Dis. 12 2 (2006) 102-111
    • (2006) Oral Dis. , vol.12 , Issue.2 , pp. 102-111
    • Nie, X.1    Luukko, K.2    Kettunen, P.3
  • 28
    • 12644290270 scopus 로고    scopus 로고
    • Identification and localization of polycystin, the PKD1 gene product
    • Geng L., Segal Y., Peissel B., Deng N., Pei Y., Carone F., et al. Identification and localization of polycystin, the PKD1 gene product. J. Clin. Invest. 98 12 (1996) 2674-2682
    • (1996) J. Clin. Invest. , vol.98 , Issue.12 , pp. 2674-2682
    • Geng, L.1    Segal, Y.2    Peissel, B.3    Deng, N.4    Pei, Y.5    Carone, F.6
  • 29
    • 0029928062 scopus 로고    scopus 로고
    • Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney
    • Ward C.J., Turley H., Ong A.C., Comley M., Biddolph S., Chetty R., et al. Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney. Proc. Natl. Acad. Sci. U. S. A. 93 4 (1996) 1524-1528
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.4 , pp. 1524-1528
    • Ward, C.J.1    Turley, H.2    Ong, A.C.3    Comley, M.4    Biddolph, S.5    Chetty, R.6
  • 30
    • 39749098357 scopus 로고    scopus 로고
    • Effects of cyclic mechanical stretching on the mRNA expression of tendon/ligament-related and osteoblast-specific genes in human mesenchymal stem cells
    • Chen Y.J., Huang C.H., Lee I.C., Lee Y.T., Chen M.H., and Young T.H. Effects of cyclic mechanical stretching on the mRNA expression of tendon/ligament-related and osteoblast-specific genes in human mesenchymal stem cells. Connect. Tissue Res. 49 1 (2008) 7-14
    • (2008) Connect. Tissue Res. , vol.49 , Issue.1 , pp. 7-14
    • Chen, Y.J.1    Huang, C.H.2    Lee, I.C.3    Lee, Y.T.4    Chen, M.H.5    Young, T.H.6
  • 31
    • 41049096935 scopus 로고    scopus 로고
    • Effect of compressive force on the expression of inflammatory cytokines and their receptors in osteoblastic Saos-2 cells
    • Koyama Y., Mitsui N., Suzuki N., Yanagisawa M., Sanuki R., Isokawa K., et al. Effect of compressive force on the expression of inflammatory cytokines and their receptors in osteoblastic Saos-2 cells. Arch. Oral Biol. 53 5 (2008) 488-496
    • (2008) Arch. Oral Biol. , vol.53 , Issue.5 , pp. 488-496
    • Koyama, Y.1    Mitsui, N.2    Suzuki, N.3    Yanagisawa, M.4    Sanuki, R.5    Isokawa, K.6
  • 32
    • 0041767267 scopus 로고    scopus 로고
    • Mechanical control of human osteoblast apoptosis and proliferation in relation to differentiation
    • Weyts F.A., Bosmans B., Niesing R., van Leeuwen J.P., and Weinans H. Mechanical control of human osteoblast apoptosis and proliferation in relation to differentiation. Calcif. Tissue Int. 72 4 (2003) 505-512
    • (2003) Calcif. Tissue Int. , vol.72 , Issue.4 , pp. 505-512
    • Weyts, F.A.1    Bosmans, B.2    Niesing, R.3    van Leeuwen, J.P.4    Weinans, H.5
  • 33
    • 0037133954 scopus 로고    scopus 로고
    • PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
    • Bhunia A.K., Piontek K., Boletta A., Liu L., Qian F., Xu P.N., et al. PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 109 2 (2002 Apr 19) 157-168
    • (2002) Cell , vol.109 , Issue.2 , pp. 157-168
    • Bhunia, A.K.1    Piontek, K.2    Boletta, A.3    Liu, L.4    Qian, F.5    Xu, P.N.6
  • 34
    • 28544433252 scopus 로고    scopus 로고
    • Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2
    • Li X., Luo Y., Starremans P.G., McNamara C.A., Pei Y., and Zhou J. Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2. Nat. Cell Biol. 7 12 (2005) 1202-1212
    • (2005) Nat. Cell Biol. , vol.7 , Issue.12 , pp. 1202-1212
    • Li, X.1    Luo, Y.2    Starremans, P.G.3    McNamara, C.A.4    Pei, Y.5    Zhou, J.6
  • 35
    • 0033391556 scopus 로고    scopus 로고
    • Identification of apoptotic cell death in distraction osteogenesis
    • Meyer T., Meyer U., Stratmann U., Wiesmann H.P., and Joos U. Identification of apoptotic cell death in distraction osteogenesis. Cell Biol. Int. 23 6 (1999) 439-446
    • (1999) Cell Biol. Int. , vol.23 , Issue.6 , pp. 439-446
    • Meyer, T.1    Meyer, U.2    Stratmann, U.3    Wiesmann, H.P.4    Joos, U.5
  • 37
    • 0036484457 scopus 로고    scopus 로고
    • Cell death of osteocytes occurs in rat alveolar bone during experimental tooth movement
    • Hamaya M., Mizoguchi I., Sakakura Y., Yajima T., and Abiko Y. Cell death of osteocytes occurs in rat alveolar bone during experimental tooth movement. Calcif. Tissue Int. 70 2 (2002) 117-126
    • (2002) Calcif. Tissue Int. , vol.70 , Issue.2 , pp. 117-126
    • Hamaya, M.1    Mizoguchi, I.2    Sakakura, Y.3    Yajima, T.4    Abiko, Y.5
  • 39
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G., and Wagner E.F. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2 4 (2002) 389-406
    • (2002) Dev. Cell , vol.2 , Issue.4 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 40
    • 0442276482 scopus 로고    scopus 로고
    • Matrix remodeling during endochondral ossification
    • Ortega N., Behonick D.J., and Werb Z. Matrix remodeling during endochondral ossification. Trends Cell Biol. 14 2 (2004) 86-93
    • (2004) Trends Cell Biol. , vol.14 , Issue.2 , pp. 86-93
    • Ortega, N.1    Behonick, D.J.2    Werb, Z.3
  • 42
    • 0242655673 scopus 로고    scopus 로고
    • Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation
    • Jiménez M.J., Balbín M., López J.M., Alvarez J., Komori T., and López-Otín C. Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation. Mol. Cell. Biol. 19 6 (1999) 4431-4442
    • (1999) Mol. Cell. Biol. , vol.19 , Issue.6 , pp. 4431-4442
    • Jiménez, M.J.1    Balbín, M.2    López, J.M.3    Alvarez, J.4    Komori, T.5    López-Otín, C.6
  • 44
    • 33746938803 scopus 로고    scopus 로고
    • Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability
    • Kamekura S., Kawasaki Y., Hoshi K., Shimoaka T., Chikuda H., Maruyama Z., et al. Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Arthritis Rheum. 54 8 (2006) 2462-2470
    • (2006) Arthritis Rheum. , vol.54 , Issue.8 , pp. 2462-2470
    • Kamekura, S.1    Kawasaki, Y.2    Hoshi, K.3    Shimoaka, T.4    Chikuda, H.5    Maruyama, Z.6
  • 45
    • 51849090143 scopus 로고    scopus 로고
    • The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease
    • Sato S., Kimura A., Ozdemir J., Asou Y., Miyazaki M., Jinno T., et al. The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease. Arthritis Rheum. 58 9 (2008) 2764-2775
    • (2008) Arthritis Rheum. , vol.58 , Issue.9 , pp. 2764-2775
    • Sato, S.1    Kimura, A.2    Ozdemir, J.3    Asou, Y.4    Miyazaki, M.5    Jinno, T.6
  • 46
    • 36949023800 scopus 로고    scopus 로고
    • Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling
    • Hopwood B., Tsykin A., Findlay D.M., and Fazzalari N.L. Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling. Arthritis Res. Ther. 9 5 (2007) R100
    • (2007) Arthritis Res. Ther. , vol.9 , Issue.5
    • Hopwood, B.1    Tsykin, A.2    Findlay, D.M.3    Fazzalari, N.L.4
  • 47
    • 34447509660 scopus 로고    scopus 로고
    • Global analyses of gene expression in early experimental osteoarthritis
    • Appleton C.T., Pitelka V., Henry J., and Beier F. Global analyses of gene expression in early experimental osteoarthritis. Arthritis Rheum. 56 6 (2007 Jun) 1854-1868
    • (2007) Arthritis Rheum. , vol.56 , Issue.6 , pp. 1854-1868
    • Appleton, C.T.1    Pitelka, V.2    Henry, J.3    Beier, F.4
  • 48
    • 45549101592 scopus 로고    scopus 로고
    • Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II
    • Xiao Z., Zhang S., Magenheimer B.S., Luo J., and Quarles L.D. Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II. J. Biol. Chem. 283 18 (2008) 12624-12634
    • (2008) J. Biol. Chem. , vol.283 , Issue.18 , pp. 12624-12634
    • Xiao, Z.1    Zhang, S.2    Magenheimer, B.S.3    Luo, J.4    Quarles, L.D.5
  • 49
    • 37449002682 scopus 로고    scopus 로고
    • Bcl-2-associated athanogene-1 (BAG-1): a transcriptional regulator mediating chondrocyte survival and differentiation during endochondral ossification
    • Tare R.S., Townsend P.A., Packham G.K., Inglis S., and Oreffo R.O. Bcl-2-associated athanogene-1 (BAG-1): a transcriptional regulator mediating chondrocyte survival and differentiation during endochondral ossification. Bone 42 1 (2008) 113-128
    • (2008) Bone , vol.42 , Issue.1 , pp. 113-128
    • Tare, R.S.1    Townsend, P.A.2    Packham, G.K.3    Inglis, S.4    Oreffo, R.O.5
  • 51
    • 0030333492 scopus 로고    scopus 로고
    • The effects of food consistency on maxillary growth in rats
    • Yamamoto S. The effects of food consistency on maxillary growth in rats. Eur. J. Orthod. 18 6 (1996) 601-615
    • (1996) Eur. J. Orthod. , vol.18 , Issue.6 , pp. 601-615
    • Yamamoto, S.1
  • 52
    • 0031792839 scopus 로고    scopus 로고
    • Fluid shear stress increases transforming growth factor beta 1 expression in human osteoblast-like cells: modulation by cation channel blockades
    • Sakai K., Mohtai M., and Iwamoto Y. Fluid shear stress increases transforming growth factor beta 1 expression in human osteoblast-like cells: modulation by cation channel blockades. Calcif. Tissue Int. 63 6 (1998) 515-520
    • (1998) Calcif. Tissue Int. , vol.63 , Issue.6 , pp. 515-520
    • Sakai, K.1    Mohtai, M.2    Iwamoto, Y.3
  • 53
    • 21244443034 scopus 로고    scopus 로고
    • Fluid shear stress synergizes with insulin-like growth factor-I (IGF-I) on osteoblast proliferation through integrin-dependent activation of IGF-I mitogenic signaling pathway
    • Kapur S., Mohan S., Baylink D.J., and Lau K.H. Fluid shear stress synergizes with insulin-like growth factor-I (IGF-I) on osteoblast proliferation through integrin-dependent activation of IGF-I mitogenic signaling pathway. J. Biol. Chem. 280 20 (2005) 20163-20170
    • (2005) J. Biol. Chem. , vol.280 , Issue.20 , pp. 20163-20170
    • Kapur, S.1    Mohan, S.2    Baylink, D.J.3    Lau, K.H.4
  • 54
    • 21744452168 scopus 로고    scopus 로고
    • Effects of cyclic tensile forces on the expression of vascular endothelial growth factor (VEGF) and macrophage-colony-stimulating factor (M-CSF) in murine osteoblastic MC3T3-E1 cells
    • Motokawa M., Kaku M., Tohma Y., Kawata T., Fujita T., Kohno S., et al. Effects of cyclic tensile forces on the expression of vascular endothelial growth factor (VEGF) and macrophage-colony-stimulating factor (M-CSF) in murine osteoblastic MC3T3-E1 cells. J. Dent. Res. 84 5 (2005) 422-427
    • (2005) J. Dent. Res. , vol.84 , Issue.5 , pp. 422-427
    • Motokawa, M.1    Kaku, M.2    Tohma, Y.3    Kawata, T.4    Fujita, T.5    Kohno, S.6
  • 56
    • 0032831465 scopus 로고    scopus 로고
    • The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia
    • Wilson P.D., Geng L., Li X., and Burrow C.R. The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia. Lab. Invest. 79 10 (1999) 1311-1323
    • (1999) Lab. Invest. , vol.79 , Issue.10 , pp. 1311-1323
    • Wilson, P.D.1    Geng, L.2    Li, X.3    Burrow, C.R.4
  • 57
    • 0034672628 scopus 로고    scopus 로고
    • Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation
    • Geng L., Burrow C.R., Li H.P., and Wilson P.D. Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation. Biochim. Biophys. Acta. 1535 1 (2000) 21-35
    • (2000) Biochim. Biophys. Acta. , vol.1535 , Issue.1 , pp. 21-35
    • Geng, L.1    Burrow, C.R.2    Li, H.P.3    Wilson, P.D.4
  • 58
    • 33750533960 scopus 로고    scopus 로고
    • AlphaVbeta3 integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes
    • Miyauchi A., Gotoh M., Kamioka H., Notoya K., Sekiya H., Takagi Y., et al. AlphaVbeta3 integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes. J. Bone Miner. Metab. 24 6 (2006) 498-504
    • (2006) J. Bone Miner. Metab. , vol.24 , Issue.6 , pp. 498-504
    • Miyauchi, A.1    Gotoh, M.2    Kamioka, H.3    Notoya, K.4    Sekiya, H.5    Takagi, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.