Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice

FASEB Journal

Volumn 25, Issue 7, 2011, Pages 2418-2432

  Xiao, Zhousheng ^a   Dallas, Mark ^b   Qiu, Ni ^a   Nicolella, Daniel ^c   Cao, Li ^a   Johnson, Mark ^b   Bonewald, Lynda ^b   Quarles, L Darryl ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^c SOUTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

Fluid flow; Mechanical loading; Polycystin 1

Indexed keywords

CALCIUM ION; GENOMIC DNA; POLYCYSTIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITOMETRY; BONE DENSITY; CALCIUM CELL LEVEL; CONTROLLED STUDY; DEVICE; FEMUR; GENE DOSAGE; GENE EXPRESSION; GENOTYPE; LOADING TEST; MECHANICAL STRESS; MECHANOTRANSDUCTION; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCYTE; PERIOSTEUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SHEAR STRESS; SKELETON; TRABECULAR BONE;

ANIMALS; BONE AND BONES; BONE DENSITY; BONE DISEASES, METABOLIC; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; MALE; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOCALCIN; OSTEOCYTES; PROTEIN KINASE C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRESS, MECHANICAL; WEIGHT-BEARING;

MUS;

EID: 79960169162     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-180299     Document Type: Article

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