Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Sethi, Gautam ^a,b   Chatterjee, Snehajyoti ^c   Rajendran, Peramaiyan ^a   Li, Feng ^a   Shanmugam, Muthu K ^a   Wong, Kwong F ^a,b   Kumar, Alan P ^a,b,d,e   Senapati, Parijat ^c   Behera, Amit K ^c   Hui, Kam M ^f   Basha, Jeelan ^c   Natesh, Nagashayana ^g   Luk, John M ^a,b,f   Kundu, Tapas K ^c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

^d CURTIN UNIVERSITY   (Australia)

^e UNIVERSITY OF NORTH TEXAS   (United States)

^f INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^g Central Government Health Scheme Dispensary No 3   (India)

Author keywords

Acetylation; Apoptosis; Garcinol; HCC; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; BENZOPHENONE DERIVATIVE; CYCLIN D1; GARCINOL; INTERLEUKIN 6; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; STAT3 PROTEIN; SURVIVIN; UNCLASSIFIED DRUG; VASCULOTROPIN; STAT3 PROTEIN, HUMAN; TERPENE;

ACETYLATION; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL SURVIVAL; DIMERIZATION; DNA BINDING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARCINOMA, HEPATOCELLULAR; DRUG EFFECTS; GENETICS; LIVER NEOPLASMS; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ACETYLATION; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DIMERIZATION; HUMANS; LIVER NEOPLASMS; MICE; PHOSPHORYLATION; STAT3 TRANSCRIPTION FACTOR; TERPENES;

EID: 84897504974     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-66     Document Type: Article

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