Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling

Clinical Immunology

Volumn 152, Issue 1-2, 2014, Pages 101-110

  Lee, Naeun ^a   Shin, Min Sun ^a   Kang, Ki Soo ^a,b   Yoo, Seung Ah ^a   Mohanty, Subhasis ^a   Montgomery, Ruth R ^a   Shaw, Albert C ^a   Kang, Insoo ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Jeju National University School of Medicine   (South Korea)

Author keywords

Human; IFN ; IL 15; Monocytes and aging

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; GAMMA INTERFERON RECEPTOR 1; GAMMA INTERFERON RECEPTOR 2; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; AGING; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; GENE EXPRESSION; HOST RESISTANCE; HUMAN; HUMAN CELL; INFLAMMATION; INTERFERON INDUCTION; MALE; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

HUMAN; IFN-Γ; IL-15; MONOCYTES AND AGING;

ADULT; AGE FACTORS; AGING; HUMANS; INFLAMMATION; INTERFERON REGULATORY FACTOR-1; INTERFERON-GAMMA; INTERLEUKIN-15; MIDDLE AGED; MONOCYTES; RECEPTORS, INTERFERON; RECEPTORS, INTERLEUKIN-15; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR;

EID: 84897488461     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2014.03.003     Document Type: Article

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