Transgenic mice that overexpress human IL-15 in enterocytes recapitulate both B and T cell-mediated pathologic manifestations of celiac disease

Journal of Clinical Immunology

Volumn 31, Issue 6, 2011, Pages 1038-1044

  Yokoyama, Seiji ^a   Takada, Kazuko ^c   Hirasawa, Masatomo ^c   Perera, Liyanage P ^b   Hiroi, Takachika ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NIHON UNIVERSITY   (Japan)

Author keywords

Autoantibodies; Autoimmune diseases; Celiac disease; IL 15; Plasmacytosis

Indexed keywords

AUTOANTIBODY; INTERLEUKIN 5; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; B LYMPHOCYTE ACTIVATION; CELIAC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; INTESTINE CELL; LAMINA PROPRIA; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PLASMACYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTES; CELIAC DISEASE; CELL MOVEMENT; DISEASE MODELS, ANIMAL; ENTEROCYTES; GTP-BINDING PROTEINS; HUMANS; INFLAMMATION; INTERLEUKIN-15; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; PLASMA CELLS; T-LYMPHOCYTES; TRANSGENES; TRANSGLUTAMINASES;

EID: 84857059940     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-011-9586-7     Document Type: Article

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