PPARγ accelerates cellular senescence by inducing p16INK4α expression in human diploid fibroblasts

Journal of Cell Science

Volumn 121, Issue 13, 2008, Pages 2235-2245

  Gan, Qini ^a   Huang, Jing ^a   Zhou, Rui ^a   Niu, Jing ^a   Zhu, Xiaojun ^a   Wang, Jing ^a   Zhang, Zongyu ^a   Tong, Tanjun ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Cellular senescence; Fibroblast; p16INK4 ; PPAR

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST;

ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL GROWTH; CONTROLLED STUDY; DIPLOIDY; EMBRYO; FEMALE; FETUS; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SENESCENCE; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING;

CELL AGING; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DIPLOIDY; FIBROBLASTS; HUMANS; PHOSPHORYLATION; PPAR GAMMA; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 48049108701     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.026633     Document Type: Article

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