Aging-related changes in cutaneous corticotropin-releasing hormone system reflect a defective neuroendocrine-stress response in aging

Rejuvenation Research

Volumn 15, Issue 4, 2012, Pages 366-373

  Elewa, Rana Mohsen ^a,b   Abdallah, Marwa ^b   Youssef, Nagwa ^b   Zouboulis, Christos C ^a  

^a DESSAU MEDICAL CENTER   (Germany)

^b AIN SHAMS UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; HORMONE BINDING PROTEIN;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; CHILD; CLINICAL ARTICLE; DISEASE ASSOCIATION; EPIDERMIS; FEMALE; GROWTH, DEVELOPMENT AND AGING DISORDERS; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NEUROENDOCRINOLOGY; PRIORITY JOURNAL; SCHOOL CHILD; SEBACEOUS GLAND; STRESS;

ADULT; AGED; AGING; CARRIER PROTEINS; CORTICOTROPIN-RELEASING HORMONE; FEMALE; HUMANS; MALE; MIDDLE AGED; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SEBACEOUS GLANDS; SKIN; STRESS, PHYSIOLOGICAL; YOUNG ADULT;

EID: 84864947957     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2011.1294     Document Type: Article

References (21)

1. Bove M, Carnevali L, Cicero AF, Grandi E, Gaddoni M, Noera G, Gaddi AV. Psychosocial factors and metabolic parameters: Is there any association in elderly people? The Massa Lombarda Project. Aging Ment Health 2010;14:801-806.
2. Cai A, Wise PM. Age-related changes in the diurnal rhythm of CRH gene expression in the paraventricular nuclei. Am J Physiol 1996;270:E238-E243.
3. Otte C, Hart S, Neylan TC, Marmar CR, Yaffe K, Mohr DC. A meta-analysis of cortisol response to challenge in human aging: Importance of gender. Psychoneuroendocrinology 2005;30:80-91. (Pubitemid 39195047)
4. Raadsheer FC, Oorschot DE, Verwer RW, Tilders FJ, Swaab DF. Age-related increase in the total number of corticotropin-releasing hormone neurons in the human paraventricular nucleus in controls and Alzheimer's disease: Comparison of the disector with an unfolding method. J Comp Neurol 1994;15;339:447-457. (Pubitemid 24012954)
5. Hauger RL, Thrivikraman KV, Plotsky PM. Age-related alterations of hypothalamic-pituitary-adrenal axis function in male Fischer 344 rats. Endocrinology 1994;134:1528-1536. (Pubitemid 24085613)
6. Swaab DF, Bao AM, Lucassen PJ. The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 2005;4:141-194. (Pubitemid 41114861)
7. Cizza G, Calogero AE, Brady LS, Bagdy G, Bergamini E, Blackman MR, Chrousos GP, Gold PW. Male Fischer 344/N rats show a progressive central impairment of the hypothalamic-pituitary-adrenal axis with advancing age. Endocrinology 1994;134:1611-1620. (Pubitemid 24110714)
8. Kasckow JW, Regmi A, Mulchahey JJ, Plotsky PM, Hauger RL. Changes in brain corticotropin-releasing factor messenger RNA expression in aged Fischer 344 rats. Brain Res 1999;822:228-230. (Pubitemid 29222846)
9. Slominski A, Wortsman J, Pisarchik A, Zbytek B, Linton EA, Mazurkiewicz JE, Wei ET. Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors. FASEB J 2001;15:1678-1693. (Pubitemid 32730215)
10. Slominski A, Pisarchik A, Tobin DJ, Mazurkiewicz JE, Wortsman J. Differential expression of a cutaneous corticotropin-releasing hormone system. Endocrinology 2004;145: 941-950. (Pubitemid 38183838)
11. Slominski A, Ermak G, Mazurkiewicz JE, Baker J, Wortsman J. Characterization of corticotropin-releasing hormone (CRH) in human skin. J Clin Endocrinol Metab 1998;83: 1020-1024. (Pubitemid 28496487)
12. Ganceviciene R, Graziene V, Fimmel S, Zouboulis CC. Involvement of the corticotropin-releasing hormone system in the pathogenesis of acne vulgaris. Br J Dermatol 2009;160:345-352.
13. Slominski A, Wortsman J, Luger T, Paus R, Solomon S. Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol Rev 2000;80:979-1020. (Pubitemid 30452009)
14. Krause K, Schnitger A, Fimmel S, Glass E, Zouboulis CC. Corticotropin-releasing hormone skin signaling is receptormediated and is predominant in the sebaceous glands. Horm Metab Res 2007;39:166-170. (Pubitemid 46535575)
15. Zouboulis CC, Seltmann H, Hiroi N, Chen W, Young M, Oeff M, Scherbaum WA, Orfanos CE, McCann SM, Bornstein SR. Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes. Proc Natl Acad Sci USA 2002;99:7148-7153. (Pubitemid 34526270)
16. Zouboulis CC, Boschnakow A. Chronological ageing and photoageing of the human sebaceous gland. Clin Exp Dermatol 2001;26:600-607. (Pubitemid 32989585)
17. Ziegler CG, Krug AW, Zouboulis CC, Bornstein SR. Corticotropin releasing hormone and its function in the skin. Horm Metab Res 2007;39:106-109. (Pubitemid 46535568)
18. Makrantonaki E, Adjaye J, Herwig R, Brink TC, Groth D, Hultschig C, Lehrach H, Zouboulis CC. Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro. Aging Cell 2006;5:331-344. (Pubitemid 44109063)
19. Pedersen WA, McCullers D, Culmsee C, Haughey NJ, Herman JP, Mattson MP. Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease. Neurobiol Dis 2001;8:492-503. (Pubitemid 32566139)
20. Makrantonaki E, Schönknecht P, Hossini AM, Kaiser E, Katsouli M-M, Adjaye J, Schröder J, Zouboulis CC. Skin and brain age together: The role of hormones in the ageing process. Exp Gerontol 2010;45:801-813.
21. Slominski A. On the role of the corticotropin-releasing hormone signalling system in the aetiology of inflammatory skin disorders. Br J Dermatol 2009, 160:229-232.