HIV-2 Vpx protein interacts with interferon regulatory factor 5 (IRF5) and inhibits its function

Journal of Biological Chemistry

Volumn 289, Issue 13, 2014, Pages 9146-9157

  Cheng, Xiaogang ^a   Ratner, Lee ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; GLYCOPROTEINS;

BINDING ACTIVITIES; CELL GROWTH REGULATION; CHROMATIN IMMUNOPRECIPITATION ASSAY; INTERFERON REGULATORY FACTORS; LIPOPOLYSACCHARIDES; PRO-INFLAMMATORY CYTOKINES; PROTEIN PRODUCTION; TYPE I INTERFERONS;

INTERFERONS;

HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 12P40; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VPX PROTEIN; CARRIER PROTEIN; CYTOKINE; DNA; INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, HUMAN; PROTEIN BINDING; VIRUS PROTEIN; VPRBP PROTEIN, HUMAN; VPX PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 2;

ARTICLE; BINDING AFFINITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; IL12P40 GENE; IMMUNE EVASION; INNATE IMMUNITY; INTERLEUKIN 6 GENE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; TRANSACTIVATION; TUMOR NECROSIS FACTOR ALPHA GENE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; GENETICS; HEK293 CELL LINE; HUMAN IMMUNODEFICIENCY VIRUS 2; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION; VIRUS REPLICATION;

CARRIER PROTEINS; CYTOKINES; DNA; HEK293 CELLS; HIV-2; HUMANS; INTERFERON REGULATORY FACTORS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANSCRIPTIONAL ACTIVATION; VIRAL REGULATORY AND ACCESSORY PROTEINS; VIRUS REPLICATION;

EID: 84897420352     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.534321     Document Type: Article

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