Functional analysis of a dominant negative mutation of interferon regulatory factor 5

PLoS ONE

Volumn 4, Issue 5, 2009, Pages

  Yang, Long ^a,b   Zhao, Tiejun ^a   Shi, Xiaoliu ^a,c   Nakhaei, Peyman ^a,b   Wang, Yunling ^a   Sun, Qiang ^a   Hiscott, John ^a,b   Lin, Rongtuan ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; CPG OLIGODEOXYNUCLEOTIDE; DNA; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 12P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PROLINE; TOLL LIKE RECEPTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; INTERFERON REGULATORY FACTOR; INTERLEUKIN 12; IRF5 PROTEIN, HUMAN; IRF5 PROTEIN, MOUSE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL LINE; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MISSENSE MUTATION; MUTANT; NONHUMAN; PHENOTYPE; PLASMID; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; START CODON; T CELL LEUKEMIA; T LYMPHOCYTE; VIRUS INFECTION; WILD TYPE; ANIMAL; BLOOD; CYTOLOGY; DOMINANT GENE; DRUG EFFECT; GENETICS; IMMUNOPRECIPITATION; LEUKEMIA CELL LINE; LYMPHOCYTE; METABOLISM; MONOCYTE; MOUSE; PATHOLOGY; PHYSIOLOGY; PROTEIN BINDING; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENES, DOMINANT; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTERFERON REGULATORY FACTORS; INTERLEUKIN-12; INTERLEUKIN-6; JURKAT CELLS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LEUKEMIA-LYMPHOMA, ADULT T-CELL; LIPOPOLYSACCHARIDES; LYMPHOCYTES; MICE; MONOCYTES; MUTANT PROTEINS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTIONAL ACTIVATION;

EID: 65549099807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005500     Document Type: Article

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