-
1
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J, (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
2
-
-
38149056462
-
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs
-
Alejandre-Alcazar MA, Michiels-Corsten M, Vicencio AG, Reiss I, Ryu J, et al. (2008) TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn 237: 259-269.
-
(2008)
Dev Dyn
, vol.237
, pp. 259-269
-
-
Alejandre-Alcazar, M.A.1
Michiels-Corsten, M.2
Vicencio, A.G.3
Reiss, I.4
Ryu, J.5
-
3
-
-
33646562542
-
The logic of TGFbeta signaling
-
Massague J, Gomis RR, (2006) The logic of TGFbeta signaling. FEBS Lett 580: 2811-2820.
-
(2006)
FEBS Lett
, vol.580
, pp. 2811-2820
-
-
Massague, J.1
Gomis, R.R.2
-
4
-
-
33745808765
-
Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis
-
Sheppard D, (2006) Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc Am Thorac Soc 3: 413-417.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 413-417
-
-
Sheppard, D.1
-
5
-
-
2542609844
-
Smad3 as a mediator of the fibrotic response
-
Flanders KC, (2004) Smad3 as a mediator of the fibrotic response. Int J Exp Pathol 85: 47-64.
-
(2004)
Int J Exp Pathol
, vol.85
, pp. 47-64
-
-
Flanders, K.C.1
-
6
-
-
33744944779
-
Epithelial origin of myofibroblasts during fibrosis in the lung
-
Willis BC, duBois RM, Borok Z, (2006) Epithelial origin of myofibroblasts during fibrosis in the lung. Proc Am Thorac Soc 3: 377-382.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 377-382
-
-
Willis, B.C.1
duBois, R.M.2
Borok, Z.3
-
7
-
-
26444585020
-
Transforming growth factor-beta signaling in stem cells and cancer
-
Mishra L, Derynck R, Mishra B, (2005) Transforming growth factor-beta signaling in stem cells and cancer. Science 310: 68-71.
-
(2005)
Science
, vol.310
, pp. 68-71
-
-
Mishra, L.1
Derynck, R.2
Mishra, B.3
-
8
-
-
3543109115
-
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis
-
Lee CG, Cho SJ, Kang MJ, Chapoval SP, Lee PJ, et al. (2004) Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med 200: 377-389.
-
(2004)
J Exp Med
, vol.200
, pp. 377-389
-
-
Lee, C.G.1
Cho, S.J.2
Kang, M.J.3
Chapoval, S.P.4
Lee, P.J.5
-
9
-
-
34548329486
-
Differentiation plasticity regulated by TGF-beta family proteins in development and disease
-
Derynck R, Akhurst RJ, (2007) Differentiation plasticity regulated by TGF-beta family proteins in development and disease. Nat Cell Biol 9: 1000-1004.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1000-1004
-
-
Derynck, R.1
Akhurst, R.J.2
-
10
-
-
30944466813
-
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
-
Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, et al. (2006) Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. Cytokine Growth Factor Rev 17: 19-27.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 19-27
-
-
Roberts, A.B.1
Tian, F.2
Byfield, S.D.3
Stuelten, C.4
Ooshima, A.5
-
12
-
-
23044466047
-
Specificity and versatility in tgf-beta signaling through Smads
-
Feng XH, Derynck R, (2005) Specificity and versatility in tgf-beta signaling through Smads. Annu Rev Cell Dev Biol 21: 659-693.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
13
-
-
0033367321
-
Regulation and regulatory activities of transforming growth factor beta
-
Bonewald LF, (1999) Regulation and regulatory activities of transforming growth factor beta. Crit Rev Eukaryot Gene Expr 9: 33-44.
-
(1999)
Crit Rev Eukaryot Gene Expr
, vol.9
, pp. 33-44
-
-
Bonewald, L.F.1
-
14
-
-
0029742706
-
Transforming growth factor-beta: a general review
-
Lawrence DA, (1996) Transforming growth factor-beta: a general review. Eur Cytokine Netw 7: 363-374.
-
(1996)
Eur Cytokine Netw
, vol.7
, pp. 363-374
-
-
Lawrence, D.A.1
-
15
-
-
34247539528
-
A tale of two proteins: Differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling
-
Brown KA, Pietenpol JA, Moses HL, (2007) A tale of two proteins: Differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling. J Cell Biochem 101: 9-33.
-
(2007)
J Cell Biochem
, vol.101
, pp. 9-33
-
-
Brown, K.A.1
Pietenpol, J.A.2
Moses, H.L.3
-
16
-
-
33847210725
-
Effect of TGF-beta/Smad signaling pathway on lung myofibroblast differentiation
-
Gu L, Zhu YJ, Yang X, Guo ZJ, Xu WB, et al. (2007) Effect of TGF-beta/Smad signaling pathway on lung myofibroblast differentiation. Acta Pharmacol Sin 28: 382-391.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 382-391
-
-
Gu, L.1
Zhu, Y.J.2
Yang, X.3
Guo, Z.J.4
Xu, W.B.5
-
17
-
-
2142646426
-
TGF-beta signaling and the fibrotic response
-
Leask A, Abraham DJ, (2004) TGF-beta signaling and the fibrotic response. FASEB J 18: 816-827.
-
(2004)
FASEB J
, vol.18
, pp. 816-827
-
-
Leask, A.1
Abraham, D.J.2
-
18
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn T, (2008) Cellular and molecular mechanisms of fibrosis. J Pathol 214: 199-210.
-
(2008)
J Pathol
, vol.214
, pp. 199-210
-
-
Wynn, T.1
-
19
-
-
36148956552
-
Transforming growth factor beta1 induces epithelial-to-mesenchymal transition of A549 cells
-
Kim JH, Jang YS, Eom KS, Hwang YI, Kang HR, et al. (2007) Transforming growth factor beta1 induces epithelial-to-mesenchymal transition of A549 cells. J Korean Med Sci 22: 898-904.
-
(2007)
J Korean Med Sci
, vol.22
, pp. 898-904
-
-
Kim, J.H.1
Jang, Y.S.2
Eom, K.S.3
Hwang, Y.I.4
Kang, H.R.5
-
20
-
-
33748375828
-
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
-
Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, et al. (2006) Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A 103: 13180-13185.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13180-13185
-
-
Kim, K.K.1
Kugler, M.C.2
Wolters, P.J.3
Robillard, L.4
Galvez, M.G.5
-
21
-
-
24644487312
-
TGF-beta and epithelial-to-mesenchymal transitions
-
Zavadil J, Bottinger EP, (2005) TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 24: 5764-5774.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
22
-
-
25444457220
-
Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder
-
Selman M, Pardo A, (2002) Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder. Respir Res 3: 3.
-
(2002)
Respir Res
, vol.3
, pp. 3
-
-
Selman, M.1
Pardo, A.2
-
23
-
-
17844384822
-
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis
-
Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, et al. (2005) Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 166: 1321-1332.
-
(2005)
Am J Pathol
, vol.166
, pp. 1321-1332
-
-
Willis, B.C.1
Liebler, J.M.2
Luby-Phelps, K.3
Nicholson, A.G.4
Crandall, E.D.5
-
24
-
-
0036177427
-
Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation
-
Verrecchia F, Mauviel A, (2002) Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation. J Invest Dermatol 118: 211-215.
-
(2002)
J Invest Dermatol
, vol.118
, pp. 211-215
-
-
Verrecchia, F.1
Mauviel, A.2
-
25
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG, (2003) Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
26
-
-
33747506955
-
Membrane type-matrix metalloproteinases in idiopathic pulmonary fibrosis
-
Garcia-Alvarez J, Ramirez R, Sampieri CL, Nuttall RK, Edwards DR, et al. (2006) Membrane type-matrix metalloproteinases in idiopathic pulmonary fibrosis. Sarcoidosis Vasc Diffuse Lung Dis 23: 13-21.
-
(2006)
Sarcoidosis Vasc Diffuse Lung Dis
, vol.23
, pp. 13-21
-
-
Garcia-Alvarez, J.1
Ramirez, R.2
Sampieri, C.L.3
Nuttall, R.K.4
Edwards, D.R.5
-
27
-
-
8144226794
-
Idiopathic pulmonary fibrosis: misunderstandings between epithelial cells and fibroblasts?
-
Selman M, Pardo A, (2004) Idiopathic pulmonary fibrosis: misunderstandings between epithelial cells and fibroblasts? Sarcoidosis Vasc Diffuse Lung Dis 21: 165-172.
-
(2004)
Sarcoidosis Vasc Diffuse Lung Dis
, vol.21
, pp. 165-172
-
-
Selman, M.1
Pardo, A.2
-
28
-
-
0037474330
-
Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest
-
Nicolas FJ, Lehmann K, Warne PH, Hill CS, Downward J, (2003) Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest. J Biol Chem 278: 3251-3256.
-
(2003)
J Biol Chem
, vol.278
, pp. 3251-3256
-
-
Nicolas, F.J.1
Lehmann, K.2
Warne, P.H.3
Hill, C.S.4
Downward, J.5
-
29
-
-
0036024955
-
Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation
-
Weinmann AS, Farnham PJ, (2002) Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods 26: 37-47.
-
(2002)
Methods
, vol.26
, pp. 37-47
-
-
Weinmann, A.S.1
Farnham, P.J.2
-
30
-
-
84984933073
-
Structure and function of a transcriptional network activated by the MAPK Hog1
-
Capaldi AP, Kaplan T, Liu Y, Habib N, Regev A, et al. (2008) Structure and function of a transcriptional network activated by the MAPK Hog1. Nat Genet 40: 1300-1306.
-
(2008)
Nat Genet
, vol.40
, pp. 1300-1306
-
-
Capaldi, A.P.1
Kaplan, T.2
Liu, Y.3
Habib, N.4
Regev, A.5
-
31
-
-
2642572859
-
TRANSFAC, TRANSPATH and CYTOMER as starting points for an ontology of regulatory networks
-
Wingender E, (2004) TRANSFAC, TRANSPATH and CYTOMER as starting points for an ontology of regulatory networks. In Silico Biol 4: 55-61.
-
(2004)
In Silico Biol
, vol.4
, pp. 55-61
-
-
Wingender, E.1
-
32
-
-
58149200952
-
UniPROBE: an online database of protein binding microarray data on protein-DNA interactions
-
Newburger DE, Bulyk ML, (2009) UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic Acids Res 37: D77-82.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 77-82
-
-
Newburger, D.E.1
Bulyk, M.L.2
-
33
-
-
2942558697
-
On the power of profiles for transcription factor binding site detection
-
Article7
-
Rahmann S, Muller T, Vingron M, (2003) On the power of profiles for transcription factor binding site detection. Stat Appl Genet Mol Biol 2: Article7.
-
(2003)
Stat Appl Genet Mol Biol
, vol.2
-
-
Rahmann, S.1
Muller, T.2
Vingron, M.3
-
34
-
-
31044448265
-
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression
-
Jinnin M, Ihn H, Tamaki K, (2006) Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol 69: 597-607.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 597-607
-
-
Jinnin, M.1
Ihn, H.2
Tamaki, K.3
-
35
-
-
30344482268
-
Comparison of normalization methods for CodeLink Bioarray data
-
Wu W, Dave N, Tseng GC, Richards T, Xing EP, et al. (2005) Comparison of normalization methods for CodeLink Bioarray data. BMC Bioinformatics 6: 309.
-
(2005)
BMC Bioinformatics
, vol.6
, pp. 309
-
-
Wu, W.1
Dave, N.2
Tseng, G.C.3
Richards, T.4
Xing, E.P.5
-
36
-
-
24944463801
-
Analysis of microarray experiments for pulmonary fibrosis
-
Dave NB, Kaminski N, (2005) Analysis of microarray experiments for pulmonary fibrosis. Methods Mol Med 117: 333-358.
-
(2005)
Methods Mol Med
, vol.117
, pp. 333-358
-
-
Dave, N.B.1
Kaminski, N.2
-
37
-
-
0041827284
-
Microarray analysis of idiopathic pulmonary fibrosis
-
Kaminski N, (2003) Microarray analysis of idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 29: S32-36.
-
(2003)
Am J Respir Cell Mol Biol
, vol.29
-
-
Kaminski, N.1
-
38
-
-
77955399498
-
Inhibition and role of let-7d in idiopathic pulmonary fibrosis
-
Pandit KV, Corcoran D, Yousef H, Yarlagadda M, Tzouvelekis A, et al. (2010) Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 182: 220-229.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 220-229
-
-
Pandit, K.V.1
Corcoran, D.2
Yousef, H.3
Yarlagadda, M.4
Tzouvelekis, A.5
-
39
-
-
43249084804
-
MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis
-
Rosas IO, Richards TJ, Konishi K, Zhang Y, Gibson K, et al. (2008) MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med 5: e93.
-
(2008)
PLoS Med
, vol.5
-
-
Rosas, I.O.1
Richards, T.J.2
Konishi, K.3
Zhang, Y.4
Gibson, K.5
-
40
-
-
67650721786
-
Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis
-
Konishi K, Gibson KF, Lindell KO, Richards TJ, Zhang Y, et al. (2009) Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 180: 167-175.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 167-175
-
-
Konishi, K.1
Gibson, K.F.2
Lindell, K.O.3
Richards, T.J.4
Zhang, Y.5
-
41
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G, (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-5121.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
42
-
-
33646344978
-
STEM: a tool for the analysis of short time series gene expression data
-
Ernst J, Bar-Joseph Z, (2006) STEM: a tool for the analysis of short time series gene expression data. BMC Bioinformatics 7: 191.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 191
-
-
Ernst, J.1
Bar-Joseph, Z.2
-
43
-
-
28644452470
-
Clustering short time series gene expression data
-
Ernst J, Nau GJ, Bar-Joseph Z, (2005) Clustering short time series gene expression data. Bioinformatics 21 (Suppl 1): i159-168.
-
(2005)
Bioinformatics
, vol.21
, Issue.SUPPL. 1
-
-
Ernst, J.1
Nau, G.J.2
Bar-Joseph, Z.3
-
44
-
-
0025730640
-
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
-
Andrews NC, Faller DV, (1991) A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 19: 2499.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 2499
-
-
Andrews, N.C.1
Faller, D.V.2
-
45
-
-
58149462180
-
-
Ingenuity Pathways Analysis, Ingenuity® Systems
-
Ingenuity® S, (2008) Ingenuity Pathways Analysis. Ingenuity Pathways Analysis Ingenuity® Systems.
-
(2008)
Ingenuity Pathways Analysis
-
-
Ingenuity, S.1
-
46
-
-
33751578696
-
Algorithms for network analysis in systems-ADME/Tox using the MetaCore and MetaDrug platforms
-
Ekins S, Bugrim A, Brovold L, Kirillov E, Nikolsky Y, et al. (2006) Algorithms for network analysis in systems-ADME/Tox using the MetaCore and MetaDrug platforms. Xenobiotica 36: 877-901.
-
(2006)
Xenobiotica
, vol.36
, pp. 877-901
-
-
Ekins, S.1
Bugrim, A.2
Brovold, L.3
Kirillov, E.4
Nikolsky, Y.5
-
47
-
-
79956324007
-
GeneGo is a leading provider of bioinformatics software solutions for data mining applications in systems biology
-
GeneGo M, (2008) GeneGo is a leading provider of bioinformatics software solutions for data mining applications in systems biology.
-
(2008)
-
-
GeneGo, M.1
-
48
-
-
44949201593
-
Transgelin is a direct target of TGF-{beta}/Smad3-dependent epithelial cell migration in lung fibrosis
-
Yu H, Konigshoff M, Jayachandran A, Handley D, Seeger W, et al. (2008) Transgelin is a direct target of TGF-{beta}/Smad3-dependent epithelial cell migration in lung fibrosis. Faseb J.
-
(2008)
Faseb J
-
-
Yu, H.1
Konigshoff, M.2
Jayachandran, A.3
Handley, D.4
Seeger, W.5
-
49
-
-
0034671506
-
Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcription
-
Zhang W, Ou J, Inagaki Y, Greenwel P, Ramirez F, (2000) Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcription. J Biol Chem 275: 39237-39245.
-
(2000)
J Biol Chem
, vol.275
, pp. 39237-39245
-
-
Zhang, W.1
Ou, J.2
Inagaki, Y.3
Greenwel, P.4
Ramirez, F.5
-
50
-
-
1342283994
-
Foxa2 regulates alveolarization and goblet cell hyperplasia
-
Wan H, Kaestner KH, Ang SL, Ikegami M, Finkelman FD, et al. (2004) Foxa2 regulates alveolarization and goblet cell hyperplasia. Development 131: 953-964.
-
(2004)
Development
, vol.131
, pp. 953-964
-
-
Wan, H.1
Kaestner, K.H.2
Ang, S.L.3
Ikegami, M.4
Finkelman, F.D.5
-
51
-
-
0027425313
-
Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm
-
Monaghan AP, Kaestner KH, Grau E, Schutz G, (1993) Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development 119: 567-578.
-
(1993)
Development
, vol.119
, pp. 567-578
-
-
Monaghan, A.P.1
Kaestner, K.H.2
Grau, E.3
Schutz, G.4
-
52
-
-
3242799550
-
Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis
-
Bonniaud P, Kolb M, Galt T, Robertson J, Robbins C, et al. (2004) Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J Immunol 173: 2099-2108.
-
(2004)
J Immunol
, vol.173
, pp. 2099-2108
-
-
Bonniaud, P.1
Kolb, M.2
Galt, T.3
Robertson, J.4
Robbins, C.5
-
53
-
-
0346727324
-
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
-
Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A, (2003) Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494.
-
(2003)
J Clin Invest
, vol.112
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
54
-
-
26844479068
-
TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis
-
Bonniaud P, Margetts PJ, Ask K, Flanders K, Gauldie J, et al. (2005) TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis. J Immunol 175: 5390-5395.
-
(2005)
J Immunol
, vol.175
, pp. 5390-5395
-
-
Bonniaud, P.1
Margetts, P.J.2
Ask, K.3
Flanders, K.4
Gauldie, J.5
-
55
-
-
58649088728
-
Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis
-
Latella G, Vetuschi A, Sferra R, Zanninelli G, D'Angelo A, et al. (2009) Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis. Eur J Clin Invest 39: 145-156.
-
(2009)
Eur J Clin Invest
, vol.39
, pp. 145-156
-
-
Latella, G.1
Vetuschi, A.2
Sferra, R.3
Zanninelli, G.4
D'Angelo, A.5
-
56
-
-
67650501166
-
Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice
-
Latella G, Vetuschi A, Sferra R, Catitti V, D'Angelo A, et al. (2009) Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice. Liver Int 29: 997-1009.
-
(2009)
Liver Int
, vol.29
, pp. 997-1009
-
-
Latella, G.1
Vetuschi, A.2
Sferra, R.3
Catitti, V.4
D'Angelo, A.5
-
57
-
-
77950873888
-
Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis
-
Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, et al. (2010) Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis. Thorax 65: 334-340.
-
(2010)
Thorax
, vol.65
, pp. 334-340
-
-
Senoo, T.1
Hattori, N.2
Tanimoto, T.3
Furonaka, M.4
Ishikawa, N.5
-
58
-
-
44949201593
-
Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis
-
Yu H, Konigshoff M, Jayachandran A, Handley D, Seeger W, et al. (2008) Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis. Faseb J 22: 1778-1789.
-
(2008)
Faseb J
, vol.22
, pp. 1778-1789
-
-
Yu, H.1
Konigshoff, M.2
Jayachandran, A.3
Handley, D.4
Seeger, W.5
-
59
-
-
17144407948
-
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis
-
Wan H, Dingle S, Xu Y, Besnard V, Kaestner KH, et al. (2005) Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem 280: 13809-13816.
-
(2005)
J Biol Chem
, vol.280
, pp. 13809-13816
-
-
Wan, H.1
Dingle, S.2
Xu, Y.3
Besnard, V.4
Kaestner, K.H.5
-
60
-
-
5144226404
-
Foxa2 is required for transition to air breathing at birth
-
Wan H, Xu Y, Ikegami M, Stahlman MT, Kaestner KH, et al. (2004) Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci U S A 101: 14449-14454.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14449-14454
-
-
Wan, H.1
Xu, Y.2
Ikegami, M.3
Stahlman, M.T.4
Kaestner, K.H.5
-
61
-
-
33749236661
-
Transcriptional regulation of perinatal lung maturation
-
Whitsett JA, Matsuzaki Y, (2006) Transcriptional regulation of perinatal lung maturation. Pediatr Clin North Am 53: 873-887, viii.
-
(2006)
Pediatr Clin North Am
, vol.53
-
-
Whitsett, J.A.1
Matsuzaki, Y.2
-
62
-
-
19644362513
-
Homeobox B3, FoxA1 and FoxA2 interactions in epithelial lung cell differentiation of the multipotent M3E3/C3 cell line
-
Yoshimi T, Nakamura N, Shimada S, Iguchi K, Hashimoto F, et al. (2005) Homeobox B3, FoxA1 and FoxA2 interactions in epithelial lung cell differentiation of the multipotent M3E3/C3 cell line. Eur J Cell Biol 84: 555-566.
-
(2005)
Eur J Cell Biol
, vol.84
, pp. 555-566
-
-
Yoshimi, T.1
Nakamura, N.2
Shimada, S.3
Iguchi, K.4
Hashimoto, F.5
-
63
-
-
2442655261
-
Forkhead box A2 transcription factor is expressed in all types of neuroendocrine lung tumors
-
Khoor A, Stahlman MT, Johnson JM, Olson SJ, Whitsett JA, (2004) Forkhead box A2 transcription factor is expressed in all types of neuroendocrine lung tumors. Hum Pathol 35: 560-564.
-
(2004)
Hum Pathol
, vol.35
, pp. 560-564
-
-
Khoor, A.1
Stahlman, M.T.2
Johnson, J.M.3
Olson, S.J.4
Whitsett, J.A.5
-
64
-
-
0037180829
-
Hydrophobic surfactant proteins in lung function and disease
-
Whitsett JA, Weaver TE, (2002) Hydrophobic surfactant proteins in lung function and disease. N Engl J Med 347: 2141-2148.
-
(2002)
N Engl J Med
, vol.347
, pp. 2141-2148
-
-
Whitsett, J.A.1
Weaver, T.E.2
-
65
-
-
38349135908
-
SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains
-
Minoo P, Hu L, Zhu N, Borok Z, Bellusci S, et al. (2008) SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains. Nucleic Acids Res 36: 179-188.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 179-188
-
-
Minoo, P.1
Hu, L.2
Zhu, N.3
Borok, Z.4
Bellusci, S.5
-
66
-
-
0037064066
-
Transforming growth factor-beta inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors
-
Li C, Zhu NL, Tan RC, Ballard PL, Derynck R, et al. (2002) Transforming growth factor-beta inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors. J Biol Chem 277: 38399-38408.
-
(2002)
J Biol Chem
, vol.277
, pp. 38399-38408
-
-
Li, C.1
Zhu, N.L.2
Tan, R.C.3
Ballard, P.L.4
Derynck, R.5
-
67
-
-
0029815021
-
Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung
-
Zhou L, Lim L, Costa RH, Whitsett JA, (1996) Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem 44: 1183-1193.
-
(1996)
J Histochem Cytochem
, vol.44
, pp. 1183-1193
-
-
Zhou, L.1
Lim, L.2
Costa, R.H.3
Whitsett, J.A.4
-
68
-
-
0028024585
-
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
-
Bohinski RJ, Di Lauro R, Whitsett JA, (1994) The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol Cell Biol 14: 5671-5681.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5671-5681
-
-
Bohinski, R.J.1
Di Lauro, R.2
Whitsett, J.A.3
-
69
-
-
79956322385
-
Role of ER Stress in EMT of Alveolar Epithelial Cells: Effects of Misfolded Surfactant Protein
-
Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, et al. (2010) Role of ER Stress in EMT of Alveolar Epithelial Cells: Effects of Misfolded Surfactant Protein. Am J Respir Cell Mol Biol.
-
(2010)
Am J Respir Cell Mol Biol
-
-
Zhong, Q.1
Zhou, B.2
Ann, D.K.3
Minoo, P.4
Liu, Y.5
-
70
-
-
77954589474
-
Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress
-
Maitra M, Wang Y, Gerard RD, Mendelson CR, Garcia CK, (2010) Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress. J Biol Chem 285: 22103-22113.
-
(2010)
J Biol Chem
, vol.285
, pp. 22103-22113
-
-
Maitra, M.1
Wang, Y.2
Gerard, R.D.3
Mendelson, C.R.4
Garcia, C.K.5
-
71
-
-
79952219426
-
Endoplasmic Reticulum Stress Induced by Surfactant Protein C Brichos Mutants Promotes Proinflammatory Signaling by Epithelial Cells
-
Maguire JA, Mulugeta S, Beers MF, (2011) Endoplasmic Reticulum Stress Induced by Surfactant Protein C Brichos Mutants Promotes Proinflammatory Signaling by Epithelial Cells. Am J Respir Cell Mol Biol 44: 404-414.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 404-414
-
-
Maguire, J.A.1
Mulugeta, S.2
Beers, M.F.3
-
72
-
-
77957273623
-
TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer
-
Yao Z, Fenoglio S, Gao DC, Camiolo M, Stiles B, et al. (2010) TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proc Natl Acad Sci U S A 107: 15535-15540.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15535-15540
-
-
Yao, Z.1
Fenoglio, S.2
Gao, D.C.3
Camiolo, M.4
Stiles, B.5
-
73
-
-
77649167803
-
Tgf-beta signaling pathway in lung adenocarcinoma invasion
-
Toonkel RL, Borczuk AC, Powell CA, (2010) Tgf-beta signaling pathway in lung adenocarcinoma invasion. J Thorac Oncol 5: 153-157.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 153-157
-
-
Toonkel, R.L.1
Borczuk, A.C.2
Powell, C.A.3
-
74
-
-
77950977675
-
TGF-beta signaling and the role of inhibitory Smads in non-small cell lung cancer
-
Jeon HS, Jen J, (2010) TGF-beta signaling and the role of inhibitory Smads in non-small cell lung cancer. J Thorac Oncol 5: 417-419.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 417-419
-
-
Jeon, H.S.1
Jen, J.2
|