A microfluidic system for investigation of extravascular transport and cellular uptake of drugs in tumors

Biotechnology and Bioengineering

Volumn 109, Issue 5, 2012, Pages 1326-1335

  Elliott, Nelita T ^a   Yuan, Fan ^a  

^a Duke University   (United States)

Author keywords

Drug transport; In vitro tumor models; Microfluidics; Multicellular structures

Indexed keywords

3D STRUCTURE; CELL DENSITY; CELLULAR UPTAKE; CENTRAL CHANNELS; DRUG TRANSPORT; EXTRACELLULAR SPACE; FLUORESCENT MOLECULES; HIGH DENSITY; HIGH RESISTANCE; HOECHST; IN-VITRO; IN-VIVO; MELANOMA CELLS; MEMBRANE-IMPERMEANT; MICRO FLUIDIC SYSTEM; MICRO-FLUIDIC DEVICES; MOLECULAR DIFFUSION; MULTICELLULAR STRUCTURE; NON-UNIFORM DISTRIBUTION; PARALLEL CHANNEL; SMALL MOLECULES; SOLID TUMORS; TUMOR CELLS; TUMOR MODELS; TUMOR TISSUES;

CELL CULTURE; CELLS; DRUG DELIVERY; FLUIDIC DEVICES; GENES; MICROFLUIDICS; MOLECULES; SODIUM; TRANSPORT PROPERTIES; TUMORS;

THREE DIMENSIONAL;

FLUORESCENT DYE;

ARTICLE; CELL DENSITY; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CELL TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; DIFFUSION; EXTRACELLULAR SPACE; IN VITRO STUDY; IN VIVO STUDY; MELANOMA CELL; MICROFLUIDICS; MICROTECHNOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; MICE; MICROFLUIDICS; MODELS, THEORETICAL; ORGAN CULTURE TECHNIQUES; PLASMACYTOMA;

EID: 84858451188     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24397     Document Type: Article

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