Microfluidic chip: Next-generation platform for systems biology

Analytica Chimica Acta

Volumn 650, Issue 1, 2009, Pages 83-97

  Feng, Xiaojun ^a   Du, Wei ^a   Luo, Qingming ^a   Liu, Bi Feng ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

C. elegans; Cell; Microfluidic chip; Omics; Systems biology

Indexed keywords

ANALYSIS TIME; ANALYTICAL TOOL; BIOLOGICAL RESEARCH; BIOLOGICAL SAMPLES; C. ELEGANS; CELLULAR LEVELS; COMPLEX BIOLOGICAL SYSTEMS; HIGH-THROUGHPUT; INDIVIDUAL COMPONENTS; MICROFLUIDIC CHIP; MICROFLUIDIC TECHNOLOGIES; MOLECULAR LEVELS; OMICS; SAMPLE CONSUMPTION; SYSTEMS BIOLOGY;

BIOLOGICAL SYSTEMS; CELL MEMBRANES; FLUIDIC DEVICES; MICROFLUIDICS;

BIOCHIPS;

ANALYTIC METHOD; CELL CULTURE; CELL SELECTION; ELECTRONICS; ELECTROPORATION; GENE SEQUENCE; GENOMICS; HIGH THROUGHPUT SCREENING; HUMAN; IMMOBILIZED CELL; MASS SPECTROMETRY; METABOLOMICS; MICROFLUIDICS; NONHUMAN; PATCH CLAMP; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEOMICS; REVIEW; SEPARATION TECHNIQUE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY;

GENOMICS; METABOLOMICS; MICROFLUIDIC ANALYTICAL TECHNIQUES; PROTEOMICS; SYSTEMS BIOLOGY;

CAENORHABDITIS ELEGANS;

EID: 69349103437     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2009.04.051     Document Type: Review

References (212)

1. Du W., Wang Y., Luo Q.M., and Liu B.F. Anal. Bioanal. Chem. 386 (2006) 444
2. Hood L., and Perlmutter M. Nat. Biotechnol. 22 (2004) 1215
3. Kirschner M.W. Cell 121 (2005) 503
4. In: Kitano H. (Ed). Foundations of Systems Biology (2001), MIT Press, Cambridge, MA
5. Kitano H. Science 295 (2002) 1662
6. Liu B.F., Xu B., Zhang G., Du W., and Luo Q.M. J. Chromatogr. A 1106 (2006) 19
7. Feng X.J., Liu X., Luo Q.M., and Liu B.F. Mass Spectrom. Rev. 27 (2008) 635
8. Manz A., Graber N., and Widmer H.M. Sens. Actuators B 1 (1990) 244
9. Watson J.D., and Crick F.H. Nature 171 (1953) 737
10. Mathies R.A., and Huang X.C. Nature 359 (1992) 167
11. Kambara H., and Takahashi S. Nature 361 (1993) 565
12. Huang X.C., Quesada M.A., and Mathies R.A. Anal. Chem. 64 (1992) 2149
13. Woolley A.T., and Mathies R.A. Proc. Nat. Acad. Sci. U.S.A. 91 (1994) 11348
14. Woolley A.T., and Mathies R.A. Anal. Chem. 67 (1995) 3676
15. Woolley A.T., Sensabaugh G.F., and Mathies R.A. Anal. Chem. 69 (1997) 2181
16. Backhouse C., Caamano M., Oaks F., Nordman E., Carrillo A., Johnson B., and Bay S. Electrophoresis 21 (2000) 150
17. Huang Z., Munro N., Huhmer A.F.R., and Landers J.P. Anal. Chem. 71 (1999) 5309
18. Liu S.R., Ren H.J., Gao Q.F., Roach D.J., Loder R.T., Armstrong T.M., Mao Q.L., Blaga I., Barker D.L., and Jovanovich S.B. Proc. Nat. Acad. Sci. U.S.A. 97 (2000) 5369
19. Simpson P.C., Roach D., Woolley A.T., Thorsen T., Johnston R., Sensabaugh G.F., and Mathies R.A. Proc. Nat. Acad. Sci. U.S.A. 95 (1998) 2256
20. Paegel B.M., Emrich C.A., Weyemayer G.J., Scherer J.R., and Mathies R.A. Proc. Nat. Acad. Sci. U.S.A. 99 (2002) 574
21. Shi Y.N., Simpson P.C., Scherer J.R., Wexler D., Skibola C., Smith M.T., and Mathies R.A. Anal. Chem. 71 (1999) 5354
22. Medintz I., Wong W.W., Berti L., Shiow L., Tom J., Scherer J., Sensabaugh G., and Mathies R.A. Genome Res. 11 (2001) 413
23. Emrich C.A., Tian H.J., Medintz I.L., and Mathies R.A. Anal. Chem. 74 (2002) 5076
24. Shi Y.N., and Anderson R.C. Electrophoresis 24 (2003) 3371
25. Kartalov E.P., and Quake S.R. Nucleic Acids Res. 32 (2004) 2873
26. Russom A., Tooke N., Andersson H., and Stemme G. Anal. Chem. 77 (2005) 7505
27. Carrilho E. Electrophoresis 21 (2000) 55
28. Medintz I.L., Paegel B.M., Blazej R.G., Emrich C.A., Berti L., Scherer J.R., and Mathies R.A. Electrophoresis 22 (2001) 3845
29. Paegel B.M., Blazej R.G., and Mathies R.A. Curr. Opin. Biotechnol. 14 (2003) 42
30. Kan C.W., Fredlake C.P., Doherty E.A.S., and Barron A.E. Electrophoresis 25 (2004) 3564
31. Sinville R., and Soper S.A. J. Sep. Sci. 30 (2007) 1714
32. Metzker M.L. Genome Res. 15 (2005) 1767
33. Riehn R., Lu M.C., Wang Y.M., Lim S.F., Cox E.C., and Austin R.H. Proc. Nat. Acad. Sci. U.S.A. 102 (2005) 10012
34. Heule M., and Manz A. Lab Chip 4 (2004) 506
35. Wang T.H., Peng Y.H., Zhang C.Y., Wong P.K., and Ho C.M. J. Am. Chem. Soc. 127 (2005) 5354
36. Kaji N., Tezuka Y., Takamura Y., Ueda M., Nishimoto T., Nakanishi H., Horiike Y., and Baba Y. Anal. Chem. 76 (2004) 15
37. Zeng Y., and Harrison D.J. Anal. Chem. 79 (2007) 2289
38. Li B.Q., Fang X.H., Luo H.B., Seo Y.S., Petersen E., Ji Y., Rafailovich M., Sokolov J., Gersappe D., and Chu B. Anal. Chem. 78 (2006) 4743
39. Lagally E.T., Medintz I., and Mathies R.A. Anal. Chem. 73 (2001) 565
40. Wang H., Chen J.F., Zhu L., Shadpour H., Hupert M.L., and Soper S.A. Anal. Chem. 78 (2006) 6223
41. Chen J.F., Wabuyele M., Chen H.W., Patterson D., Hupert M., Shadpour H., Nikitopoulos D., and Soper S.A. Anal. Chem. 77 (2005) 658
42. Chen L., West J., Auroux P.A., Manz A., and Day P.J.R. Anal. Chem. 79 (2007) 9185
43. Marcus J.S., Anderson W.F., and Quake S.R. Anal. Chem. 78 (2006) 956
44. Ottesen E.A., Hong J.W., Quake S.R., and Leadbetter J.R. Science 314 (2006) 1464
45. Song S., Singh A.K., and Kirby B.J. Anal. Chem. 76 (2004) 4589
46. Kelly R.T., Li Y., and Woolley A.T. Anal. Chem. 78 (2006) 2565
47. Wang Y.-C., Stevens A.L., and Han J. Anal. Chem. 77 (2005) 4293
48. Kim S.M., Burns M.A., and Hasselbrink E.F. Anal. Chem. 78 (2006) 4779
49. Guzman N.A. Electrophoresis 24 (2003) 3718
50. Mao X.L., Luo Y., Dai Z.P., Wang K.Y., Du Y.G., and Lin B.C. Anal. Chem. 76 (2004) 6941
51. Ramsey J.D., and Collins G.E. Anal. Chem. 77 (2005) 6664
52. Long Z.C., Shen Z., Wu D.P., Qin J.H., and Lin B.C. Lab Chip 7 (2007) 1819
53. Olvecka E., Kaniansky D., Pollak B., and Stanislawski B. Electrophoresis 25 (2004) 3865
54. Huang H., Xu F., Dai Z., and Lin B. Electrophoresis 26 (2005) 2254
55. Lin C.C., Hsu B.K., and Chen S.H. Electrophoresis 29 (2008) 1228
56. Harrison D.J., Fluri K., Seiler K., Fan Z., Effenhauser C.S., and Manz A. Science 261 (1993) 895
57. Seiler K., Harrison D.J., and Manz A. Anal. Chem. 65 (1993) 1481
58. Harrison D.J., Manz A., Fan Z., Luedi H., and Widmer H.M. Anal. Chem. 64 (1992) 1926
59. Manz A., Miyahara Y., Miura J., Watanabe Y., Miyagi H., and Sato K. Sens. Actuators B 1 (1990) 249
60. Jorgenson J.W., and Lukacs K.D. Anal. Chem. 53 (1981) 1298
61. Terabe S., Otsuka K., Ichikawa K., Tsuchiya A., and Ando T. Anal. Chem. 56 (1984) 111
62. Hjerten S., and Zhu M.D. J. Chromatogr. A 346 (1985) 265
63. Cohen A.S., Najarian A., Paulus A., Guttman A., Smith J.A., and Karger B.L. Proc. Nat. Acad. Sci. U.S.A. 85 (1988) 9660
64. Tsuda T. Anal. Chem. 59 (1987) 521
65. Duffy D.C., McDonald J.C., Schueller O.J.A., and Whitesides G.M. Anal. Chem. 70 (1998) 4974
66. Hofmann O., Che D., Cruickshank K.A., and Muller U.R. Anal. Chem. 71 (1999) 678
67. Macounova K., Cabrera C.R., Holl M.R., and Yager P. Anal. Chem. 72 (2000) 3745
68. Cabrera C.R., Finlayson B., and Yager P. Anal. Chem. 73 (2001) 658
69. Macounova K., Cabrera C.R., and Yager P. Anal. Chem. 73 (2001) 1627
70. Cui H., Horiuchi K., Dutta P., and Ivory C.F. Anal. Chem. 77 (2005) 7878
71. Cui H., Horiuchi K., Dutta P., and Ivory C.F. Anal. Chem. 77 (2005) 1303
72. Jesus D.P.D., Blanes L., and Lago C.L.D. Electrophoresis 27 (2006) 4935
73. Tan W., Fan Z.H., Qiu C.X., Ricco A.J., and Gibbons I. Electrophoresis 23 (2002) 3638
74. Throckmorton D.J., Shepodd T.J., and Singh A.K. Anal. Chem. 74 (2002) 784
75. Michels D.A., Hu S., Schoenherr R.M., Eggertson M.J., and Dovichi N.J. Mol. Cell. Proteomics 1 (2002) 69
76. Hu S., Michels D.A., Fazal M.A., Ratisoontorn C., Cunningham M.L., and Dovichi N.J. Anal. Chem. 76 (2004) 4044
77. Michels D.A., Hu S., Dambrowitz K.A., Eggertson M.J., Lauterbach K., and Dovichi N.J. Electrophoresis 25 (2004) 3098
78. Kraly J.R., Jones M.R., Gomez D.G., Dickerson J.A., Harwood M.M., Eggertson M., Paulson T.G., Sanchez C.A., Odze R., Feng Z., Reid B.J., and Dovichi N.J. Anal. Chem. 78 (2006) 5977
79. Rocklin R.D., Ramsey R.S., and Ramsey J.M. Anal. Chem. 72 (2000) 5244
80. Gottschlich N., Jacobson S.C., Culbertson C.T., and Ramsey J.M. Anal. Chem. 73 (2001) 2669
81. Ramsey J.D., Jacobson S.C., Culbertson C.T., and Ramsey J.M. Anal. Chem. 75 (2003) 3758
82. Griebel A., Rund S., Schönfeld F., Dörner W., Konrad R., and Hardt S. Lab Chip 4 (2004) 18
83. Li Y., Buch J.S., Rosenberger F., DeVoe D.L., and Lee C.S. Anal. Chem. 76 (2004) 742
84. Emrich C.A., Medintz I.L., Chu W.K., and Mathies R.A. Anal. Chem. 79 (2007) 7360
85. Herr A.E., Molho J.I., Drouvalakis K.A., Mikkelsen J.C., Utz P.J., Santiago J.G., and Kenny T.W. Anal. Chem. 75 (2003) 1180
86. Wang Y.C., Choi M.H., and Han J. Anal. Chem. 76 (2004) 4426
87. Ostrowski S.G., Kurczy M.E., Roddy T.P., Winograd N., and Ewing A.G. Anal. Chem. 79 (2007) 3554
88. Piehowski P.D., Carado A.J., Kurczy M.E., Ostrowski S.G., Heien M.L., Winograd N., and Ewing A.G. Anal. Chem. 80 (2008) 8662
89. Zheng L., McQuaw C.M., Ewing A.G., and Winograd N. J. Am. Chem. Soc. 129 (2007) 15730
90. Kurczy M.E., Kozole J., Parry S.A., Piehowski P.D., Winograd N., and Ewing A.G. Appl. Surf. Sci. 255 (2008) 1158
91. Xu B., Du W., Liu B.-F., and Luo Q. Curr. Anal. Chem. 2 (2006) 67
92. McClain M.A., Culbertson C.T., Jacobson S.C., Allbritton N.L., Sims C.E., and Ramsey J.M. Anal. Chem. 75 (2003) 5646
93. Wu H., Wheeler A., and Zare R.N. Proc. Nat. Acad. Sci. U.S.A. 101 (2004) 12809
94. Huang B., Wu H., Bhaya D., Grossman A., Granier S., Kobilka B.K., and Zare R.N. Science 315 (2007) 81
95. Gao J., Yin X.F., and Fang Z.L. Lab Chip 4 (2004) 47
96. Ling Y.Y., Yin X.F., and Fang Z.L. Electrophoresis 26 (2005) 4759
97. Ros A., Hellmich W., Regtmeier J., Duong T.T., and Anselmetti D. Electrophoresis 27 (2006) 2651
98. Aebersold R., and Mann M. Nature 422 (2003) 198
99. Li J., Kelly J.F., Chemushevich I., Harrison D.J., and Thibault P. Anal. Chem. 72 (2000) 599
100. Li J., Tremblay T.L., Wang C., Attiya S., Harrison D.J., and Thibault P. Proteomics 1 (2001) 975
101. Li J., LeRiche T., Tremblay T.L., Wang C., Bonneil E., Harrison D.J., and Thibault P. Mol. Cell. Proteomics 1 (2002) 157
102. Gustafsson M., Hirschberg D., Palmberg C., Jornvall H., and Bergman T. Anal. Chem. 76 (2004) 345
103. Wheeler A.R., Moon H., Bird C.A., Ogorzalek Loo R.R., Kim C.-J., Loo J.A., and Garrell R.L. Anal. Chem. 77 (2005) 534
104. Dodge A., Brunet E., Chen S.L., Goulpeau J., Labas V., Vinh J., and Tabeling P. Analyst 131 (2006) 1122
105. Liu Y., Qu H.Y., Xue Y., Wu Z.L., Yang P.Y., and Liu B.H. Proteomics 7 (2007) 1373
106. Culbertson C.T., Jacobson S.C., and Ramsey J.M. Anal. Chem. 72 (2000) 5814
107. Skelley A.M., Scherer J.R., Aubrey A.D., Grover W.H., Ivester R.H.C., Ehrenfreund P., Grunthaner F.J., Bada J.L., and Mathies R.A. Proc. Nat. Acad. Sci. U.S.A. 102 (2005) 1041
108. Hutt L.D., Glavin D.P., Bada J.L., and Mathies R.A. Anal. Chem. 71 (1999) 4000
109. Ro K.W., and Hahn J.H. Electrophoresis 26 (2005) 4767
110. Roper M.G., Shackman J.G., Dahlgren G.M., and Kennedy R.T. Anal. Chem. 75 (2003) 4711
111. Dishinger J.F., and Kennedy R.T. Anal. Chem. 79 (2007) 947
112. Liu B.F., Ozaki M., Hisamoto H., Luo Q.M., Utsumi Y., Hattori T., and Terabe S. Anal. Chem. 77 (2005) 573
113. Urbanski J.P., Johnson M.T., Craig D.D., Potter D.L., Gardner D.K., and Thorsen T. Anal. Chem. 80 (2008) 6500
114. Chen P., Feng X.J., Du W., and Liu B.F. Front. Biosci. 13 (2008) 2464
115. Dittrich P.S., and Schwille P. Anal. Chem. 75 (2003) 5767
116. Kang Y.J., Wu X.D., Wang Y.N., and Li D.Q. Anal. Chim. Acta 626 (2008) 97
117. Fu A.Y., Spence C., Scherer A., Arnold F.H., and Quake S.R. Nat. Biotechnol. 17 (1999) 1109
118. Fu L.M., Yang R.J., Lin C.H., Pan Y.J., and Lee G.B. Anal. Chim. Acta 507 (2004) 163
119. Yao B., Luo G.A., Feng X., Wang W., Chen L.X., and Wang Y.M. Lab Chip 4 (2004) 603
120. Fuchs A.B., Romani A., Freida D., Medoro G., Abonnenc M.L., Altomare L., Chartier I., Guergour D., Villiers C., Marche P.N., Tartagni M., Guerrieri R., Chatelain F., and Manaresi N. Lab Chip 6 (2006) 121
121. Gascoyne P., Mahidol C., Ruchirawat M., Satayavivad J., Watcharasit P., and Becker F.F. Lab Chip 2 (2002) 70
122. Hu X., Bessette P.H., Qian J., Meinhart C.D., Daugherty P.S., and Soh H.T. Proc. Nat. Acad. Sci. U.S.A. 102 (2005) 15757
123. Kim U., Qian J.R., Kenrick S.A., Daugherty P.S., and Soh H.T. Anal. Chem. 80 (2008) 8656
124. Kim U., Shu C.-W., Dane K.Y., Daugherty P.S., Wang J.Y.J., and Soh H.T. Proc. Nat. Acad. Sci. U.S.A. 104 (2007) 20708
125. Kua C.H., Lam Y.C., Rodriguez I., Yang C., and Youcef-Toumi K. Anal. Chem. 79 (2007) 6975
126. Li Y.L., Dalton C., Crabtree H.J., Nilsson G., and Kaler K.V.I.S. Lab Chip 7 (2007) 239
127. Park J., Kim B., Choi S.K., Hong S., Lee S.H., and Leed K.-I. Lab Chip 5 (2005) 1264
128. Toner M., and Irimia D. Annu. Rev. Biomed. Eng. 7 (2005) 77
129. Voldman J., Gray M.L., Toner M., and Schmidt M.A. Anal. Chem. 74 (2002) 3984
130. Vykoukal J., Vykoukal D.M., Freyberg S., Alt E.U., and Gascoyne P.R.C. Lab Chip 8 (2008) 1386
131. Safarik I., and Safarikova M. J. Chromatogr. B 722 (1999) 33
132. Han K.H., and Frazier A.B. J. Appl. Phys. 96 (2004) 5797
133. Furdui V.I., and Harrison D.J. Lab Chip 4 (2004) 461
134. Inglis D.W., Riehn R., Austin R.H., and Sturm J.C. Appl. Phys. Lett. 85 (2004) 5093
135. Lee H., Purdon A.M., and Westervelt R.M. Appl. Phys. Lett. 85 (2004) 1063
136. Pamme N., and Wilhelm C. Lab Chip 6 (2006) 974
137. Wolff A., Perch-Nielsen I.R., Larsen U.D., Friis P., Goranovic G., Poulsen C.R., Kutter J.P., and Tellemana P. Lab Chip 3 (2003) 22
138. Fu A.Y., Chou H.-P., Spence C., Arnold F.H., and Quake S.R. Anal. Chem. 74 (2002) 2451
139. Chabert M., and Viovy J.L. Proc. Nat. Acad. Sci. U.S.A. 105 (2008) 3191
140. Applegate R.W., and Squier J.J. Opt. Express 12 (2004) 4390
141. Arai F., Ng C., Maruyama H., Ichikawa A., El-Shimy H., and Fukuda T. Lab Chip 5 (2005) 1399
142. Kovac J.R., and Voldman J. Anal. Chem. 79 (2007) 9321
143. Lau A.Y., Lee L.P., and Chan J.W. Lab Chip 8 (2008) 1116
144. Perroud T.D., Kaiser J.N., Sy J.C., Lane T.W., Branda C.S., Singh A.K., and Patel K.D. Anal. Chem. 80 (2008) 6365
145. Wang M.M., Tu E., Raymond D.E., Yang J.M., Zhang H., Hagen N., Dees B., Mercer E.M., Forster A.H., Kariv I., Marchand P.J., and Butler W.F. Nat. Biotechnol. 23 (2005) 83
146. Xie C., Dinno M.A., and Li Y.-Q. Opt. Lett. 27 (2002) 249
147. Gaugiran S., Gétin S., and Fedeli J.M. Opt. Express 13 (2005) 6956
148. Grujic K., Hellesø O.G., Hole J.P., and Wilkinson J.S. Opt. Express 13 (2005) 1
149. Marchington R.F., Mazilu M., Kuriakose S., Garces-Chavez V., Reece P.J., Krauss T.F., Gu M., and Dholakia K. Opt. Express 16 (2008) 3712
150. MacDonald M.P., Spalding G.C., and Dholakia K. Nature 426 (2003) 421
151. Nilsson A., Petersson F., Jönsson H., and Laurell T. Lab Chip 4 (2004) 131
152. Petersson F., Aberg L., Sward-Nilsson A.M., and Laurell T. Anal. Chem. 79 (2007) 5117
153. Petersson F., Nilsson A., Holm C., Jönssonc H., and Laurell T. Lab Chip 5 (2004) 20
154. Adams A.A., Okagbare P.I., Feng J., Hupert M.L., Patterson D., Goettert J., McCarley R.L., Nikitopoulos D., Murphy M.C., and Soper S.A. J. Am. Chem. Soc. 130 (2008) 8633
155. Chang W.C., Lee L.P., and Liepmann D. Lab Chip 5 (2005) 64
156. Horsman K.M., Barker S.L.R., Ferrance J.P., Forrest K.A., Koen K.A., and Landers J.P. Anal. Chem. 77 (2005) 742
157. Nagrath S., Sequist L.V., Maheswaran S., Bell D.W., Irimia D., Ulkus L., Smith M.R., Kwak E.L., Digumarthy S., Muzikansky A., Ryan P., Balis U.J., Tompkins R.G., Haber D.A., and Toner M. Nature 450 (2007) 1235
158. Revzin A., Sekine K., Sin A., Tompkins R.G., and Toner M. Lab Chip 5 (2005) 30
159. Nam K.H., Chang W.J., Hong H., Lim S.M., Kim D., and Koo Y.M. Biomed. Microdevices 7 (2005) 189
160. Yamada M., Kasim V., Nakashima M., Edahiro J., and Seki M. Biotechnol. Bioeng. 88 (2004) 489
161. Ho C.T., Lin R.Z., Chang H.Y., and Liu C.H. Lab Chip 5 (2005) 1248
162. Shirasaki Y., Tanaka J., Makazu H., Tashiro K., Shoji S., Tsukita S., and Funatsu T. Anal. Chem. 78 (2006) 695
163. Kane R.S., Takayama S., Ostuni E., Ingber D.E., and Whitesides G.M. Biomaterials 20 (1999) 2363
164. Takayama S., McDonald J.C., Ostuni E., Liang M.N., Kenis P.J.A., Ismagilov R.F., and Whitesides G.M. Proc. Nat. Acad. Sci. U.S.A. 96 (1999) 5545
165. Chiu D.T., Jeon N.L., Huang S., Kane R.S., Wargo C.J., Choi I.S., Ingber D.E., and Whitesides G.M. Proc. Nat. Acad. Sci. U.S.A. 97 (2000) 2408
166. Kaji H., Nishizawa M., and Matsue T. Lab Chip 3 (2003) 208
167. Rhee S.W., Taylor A.M., Tu C.H., Cribbs D.H., Cotman C.W., and Jeon N.L. Lab Chip 5 (2005) 102
168. Di Carlo D., Wu L.Y., and Lee L.P. Lab Chip 6 (2006) 1445
169. Manbachi A., Shrivastava S., Cioffi M., Chung B.G., Moretti M., Demirci U., Yliperttula M., and Khademhosseini A. Lab Chip 8 (2008) 747
170. Evander M., Johansson L., Lilliehorn T., Piskur J., Lindvall M., Johansson S., Almqvist M., Laurell T., and Nilsson J. Anal. Chem. 79 (2007) 2984
171. Shao B., Shi L.Z., Nascimento J.M., Botvinick E.L., Ozkan M., Berns M.W., and Esener S.C. Biomed. Microdevices 9 (2007) 361
172. Chung B.G., Flanagan L.A., Rhee S.W., Schwartz P.H., Lee A.P., Monuki E.S., and Jeon N.L. Lab Chip 5 (2005) 401
173. Park J.Y., Hwang C.M., Lee S.H., and Lee S.H. Lab Chip 7 (2007) 1673
174. Kim L., Vahey M.D., Lee H.Y., and Voldman J. Lab Chip 6 (2006) 394
175. Martinoia S., Bove M., Tedesco M., Margesin B., and Grattarola M. J. Neurosci. Methods 87 (1999) 35
176. Millet L.J., Stewart M.E., Sweedler J.V., Nuzzo R.G., and Gillette M.U. Lab Chip 7 (2007) 987
177. Park J.W., Vahidi B., Taylor A.M., Rhee S.W., and Jeon N.L. Nat. Protoc. 1 (2006) 2128
178. Takayama S., Ostuni E., LeDuc P., Naruse K., Ingber D.E., and Whitesides G.M. Nature 411 (2001) 1016
179. Lucchetta E.M., Lee J.H., Fu L.A., Patel N.H., and Ismagilov R.F. Nature 434 (2005) 1134
180. Sawano A., Takayama S., Matsuda M., and Miyawaki A. Dev. Cell 3 (2002) 245
181. Neubert H.J. Anal. Chem. 76 (2004) 327A
182. Klemic K.G., Klemic J.F., Reed M.A., and Sigworth F.J. Biosens. Bioelectron. 17 (2002) 597
183. Lehnert T., Gijs M.A.M., Netzer R., and Bischoff U. Appl. Phys. Lett. 81 (2002) 5063
184. Lehnert T., Nguyen D.M.T., Baldi L., and Gijs M.A.M. Microfluid. Nanofluid. 3 (2007) 109
185. Li X.H., Klemic K.G., Reed M.A., and Sigworth F.J. Nano Lett. 6 (2006) 815
186. Sordel T., Garnier-Raveaud S., Sauter F., Pudda C., Marcel F., De Waard M., Arnoult C., Vivaudou M., Chatelain F., and Picollet-D'hahan N. J. Biotechnol. 125 (2006) 142
187. Chen C.C., and Folch A. Lab Chip 6 (2006) 1338
188. Ionescu-Zanetti C., Shaw R.M., Seo J.G., Jan Y.N., Jan L.Y., and Lee L.P. Proc. Nat. Acad. Sci. U.S.A. 102 (2005) 9112
189. Lau A.Y., Hung P.J., Wu A.R., and Lee L.P. Lab Chip 6 (2006) 1510
190. Ong W.L., Kee J.S., Ajay A., Ranganathan N., Tang K.C., and Yobas L. Appl. Phys. Lett. 89 (2006) 093902
191. Seo J., Ionescu-Zanetti C., Diamond J., Lal R., and Lee L.P. Appl. Phys. Lett. 84 (2004) 1973
192. Kim S.K., Kim J.Y., Kim K.P., and Chung T.D. Anal. Chem. 79 (2007) 7761
193. Wang J., Stine M.J., and Lu C. Anal. Chem. 79 (2007) 9584
194. Lu H., Schmidt M.A., and Jensen K.F. Lab Chip 5 (2005) 23
195. Bao N., Wang J., and Lu C. Electrophoresis 29 (2008) 2939
196. Wang J., Bao N., Paris L.L., Wang H.Y., Geahlen R.L., and Lu C. Anal. Chem. 80 (2008) 1087
197. Bao N., Zhan Y.H., and Lu C. Anal. Chem. 80 (2008) 7714
198. Klauke N., Smith G., and Cooper J.M. Lab Chip 7 (2007) 731
199. Wei C.W., Cheng J.Y., and Young T.H. Biomed. Microdevices 8 (2006) 65
200. Song X.Y., Kong B.H., and Li D. Biotechnol. Lett. 30 (2008) 1537
201. Hulme S.E., Shevkoplyas S.S., Apfeld J., Fontana W., and Whitesides G.M. Lab Chip 7 (2007) 1515
202. Chronis N., Zimmer M., and Bargmann C.I. Nat. Methods 4 (2007) 727
203. Chalasani S.H., Chronis N., Tsunozaki M., Gray J.M., Ramot D., Goodman M.B., and Bargmann C.I. Nature 450 (2007) 63
204. Rohde C.B., Zeng F., Gonzalez-Rubio R., Angel M., and Yanik M.F. Proc. Nat. Acad. Sci. U.S.A. 104 (2007) 13891
205. Chung K.H., Crane M.M., and Lu H. Nat. Methods 5 (2008) 637
206. Zeng F., Rohde C.B., and Yanik M.F. Lab Chip 8 (2008) 653
207. Guo S.X., Bourgeois F., Chokshi T., Durr N.J., Hilliard M.A., Chronis N., and Ben-Yakar A. Nat. Methods 5 (2008) 531
208. Heng X., Erickson D., Baugh L.R., Yaqoob Z., Sternberg P.W., Psaltis D., and Yang C. Lab Chip 6 (2006) 1274
209. Lange D., Storment C.W., Conley C.A., and Kovacs G.T.A. Sens. Actuators B 107 (2005) 904
210. Qin J., and Wheeler A.R. Lab Chip 7 (2007) 186
211. Kim N., Dempsey C.M., Zoval J.V., Sze J.Y., and Madou M.J. Sens. Actuators B 122 (2007) 511
212. Kim N., Dempsey C.M., Kuan C.J., Zoval J.V., O'Rourke E., Ruvkun G., Madou M.J., and Sze J.Y. Genetics 177 (2007) 835