Lab-on-a-chip technologies for oral-based cancer screening and diagnostics: Capabilities, issues, and prospects

Annals of the New York Academy of Sciences

Volumn 1098, Issue , 2007, Pages 467-475

  Mauk, Michael G ^a   Ziober, Barry L ^b   Chen, Zongyuan ^a   Thompson, Jason A ^a   Bau, Haim H ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c Utah Valley State College   (United States)

Author keywords

Cancer diagnostics; EpCAM; Lab on a chip; Microfluidics; Oral squamous cell carcinoma (OSCC)

Indexed keywords

EPITHELIAL CELL ADHESION MOLECULE; MESSENGER RNA; NUCLEIC ACID; CANCER ANTIBODY; TUMOR ANTIGEN;

CANCER CELL; CANCER DIAGNOSIS; CANCER SCREENING; CELL ISOLATION; CELL POPULATION; CELL SELECTION; CONFERENCE PAPER; CYTOLYSIS; GENE ISOLATION; GENETIC TRANSCRIPTION; LAB ON A CHIP; MICROFLUIDIC ANALYSIS; MOUTH CARCINOMA; NUCLEIC ACID AMPLIFICATION; NUCLEIC ACID ANALYSIS; SQUAMOUS CELL CARCINOMA; CHEMISTRY; ECONOMICS; FEASIBILITY STUDY; HUMAN; IMMUNOLOGY; INSTRUMENTATION; MASS SCREENING; MICROCHIP ANALYSIS; MICROFLUIDICS; MOUTH TUMOR; PATHOLOGY; PREDICTION AND FORECASTING; REVIEW;

ANTIBODIES, NEOPLASM; ANTIGENS, NEOPLASM; CARCINOMA, SQUAMOUS CELL; FEASIBILITY STUDIES; HUMANS; MASS SCREENING; MICROCHIP ANALYTICAL PROCEDURES; MICROFLUIDICS; MOUTH NEOPLASMS; PREDICTIVE VALUE OF TESTS;

EID: 34248215135     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1384.025     Document Type: Conference Paper

References (12)

1. WEINBERG, M.A. & D.J. ESTEFAN. 2002. Assessing oral malignancies. Am. Family Phys. 65: 1379-1384.
2. SOPER, S.A. et al. 2006. Point of care biosensor systems for cancer diagnostics/prognostics. Biosens. Bioelectron. 21: 1932-1942.
3. SELVAGANAPATHY, P.R., E.T. CARLEN & C.H. MASTRANGELO. 2003. Recent progress in microfluidic devices for nucleic acid and antibody assays. Proc. IEEE 91: 954-975.
4. VILKNER, T., D. JANASEK & A. MANZ. 2004. Micro total analysis systems. Recent developments. Anal. Chem. 76: 3373-3386.
5. TONER, M. & D. IRIMIA. 2005. Blood-on-a-chip. Annu. Rev. Biomed. Engng. 7: 77-103.
6. BAO, Y.P. et al. 2006. Detection of protein analytes via nanoparticle-based bio bar code technology. Anal. Chem. 78: 2055-2059.
7. THAXTON, C.S., D.G. GEORGANOPOULOU & C.A. MIRKIN. 2006. Gold nanoparticle probes for the detection of nucleic acid targets. Clinica Chimica Acta 363: 120-126.
8. WENT, P.T. et al. 2004. Frequent EpCAM protein expression in human carcinomas. Human Pathol. 35: 122-128.
9. SAUK, J.J., N. NIKITAKIS & H. SIAVASH. 2005. Hsp 47, a novel collagen binding serpin chaperone, autoantigen, and therapeutic agent. Front Biosci. 10: 107-118.
10. ZIOBER, A.F. et al. 2006. Identification of a gene signature for rapid screening of oral squamous cell carcinoma. Clin. Cancer Res. 20: 5960-5971.
11. BERTHIER, J. & P. SILBERZAN. 2006. Microfluidics for Biotechnology. Artech House. Norwood, MA.
12. WEIGL, B.H. et al. 2006. Fully integrated multiplexed lab-on-a-card assay for enteric pathogens. Microfluidics, BioMEMS, and Medical Microsystems. Proc. SPIE 6112: 611202.