Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system

Biotechnology and Bioengineering

Volumn 110, Issue 3, 2013, Pages 958-968

  Yang, Ying ^a   Li, Jianzhou ^a   Pan, Xiaoping ^a   Zhou, Pengcheng ^a   Yu, Xiaopeng ^a   Cao, Hongcui ^a   Wang, Yingjie ^a   Li, Lanjuan ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Bioartificial liver; Fluidized bed bioreactor; Human placental mesenchymal stem cells (hPMSC); Microspheres

Indexed keywords

BIOARTIFICIAL LIVER; CO-CULTURE SYSTEM; COCULTURE; DRUG METABOLISMS; EXTRACELLULAR CUES; FLUIDIZED BED BIOREACTORS; IN-VITRO; LIVER CELLS; MESENCHYMAL STEM CELL; METABOLIC FUNCTION; MICROENVIRONMENTS; SIGNALING PATHWAYS; THREE-DIMENSIONAL CULTURE SYSTEM; UREA SYNTHESIS;

ARTIFICIAL ORGANS; BIOCONVERSION; BIOREACTORS; CELLS; ENZYME ACTIVITY; FLUIDIZATION; FLUIDIZED BEDS; METABOLISM; MICROSPHERES; PHYSIOLOGY; THREE DIMENSIONAL; UREA;

CELL CULTURE;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALBUMIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450 1A2; CYTOCHROME P450 3A4; MICROSPHERE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C; PROTEOME; THREONINE; UREA;

ARTICLE; BIOARTIFICIAL LIVER; BIOREACTOR; CELL METABOLISM; COCULTURE; CONTROLLED STUDY; DRUG METABOLISM; FLOW CYTOMETRY; FLUIDIZATION; FLUIDIZED BIOREACTOR; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIVER CELL; LIVER METABOLISM; MESENCHYMAL STEM CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSLATION; SIGNAL TRANSDUCTION; UREA CYCLE; WESTERN BLOTTING;

ALBUMINS; BIOREACTORS; COCULTURE TECHNIQUES; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; LIVER, ARTIFICIAL; MESENCHYMAL STROMAL CELLS; MICROSPHERES; SIGNAL TRANSDUCTION; UREA;

EID: 84872658891     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24752     Document Type: Article

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