-
1
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
3
-
-
0033861419
-
The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products
-
Bowie A., O'Neill L.A. The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products. J. Leukocyte Biol. 2000, 67:508-514.
-
(2000)
J. Leukocyte Biol.
, vol.67
, pp. 508-514
-
-
Bowie, A.1
O'Neill, L.A.2
-
4
-
-
84891146679
-
Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: The functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells
-
Brietzke A., Goldammer T., Rebl H., Korytář T., Köllner B., Yang W., Rebl A., Seyfert H.M. Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: The functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells. Fish Shellfish Immunol. 2014, 36:206-214.
-
(2014)
Fish Shellfish Immunol.
, vol.36
, pp. 206-214
-
-
Brietzke, A.1
Goldammer, T.2
Rebl, H.3
Korytář, T.4
Köllner, B.5
Yang, W.6
Rebl, A.7
Seyfert, H.M.8
-
5
-
-
0029865142
-
IRAK: a kinase associated with the interleukin-1 receptor
-
Cao Z., Henzel W.J., Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science 1996, 271:1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
6
-
-
33845316120
-
Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop
-
Cheng H., Addona T., Keshishian H., Dahlstrand E., Lu C., Dorsch M., Li Z., Wang A., Ocain T.D., Li P., Parsons T.F., Jaffee B., Xu Y. Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop. Biochem. Biophys. Res. Commun. 2007, 352:609-616.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.352
, pp. 609-616
-
-
Cheng, H.1
Addona, T.2
Keshishian, H.3
Dahlstrand, E.4
Lu, C.5
Dorsch, M.6
Li, Z.7
Wang, A.8
Ocain, T.D.9
Li, P.10
Parsons, T.F.11
Jaffee, B.12
Xu, Y.13
-
7
-
-
0242715836
-
Cryptocaryon irritans Brown 1951, the cause of 'white spot disease' in marine fish: an update
-
Colorni A., Burgess P. Cryptocaryon irritans Brown 1951, the cause of 'white spot disease' in marine fish: an update. Aquat. Sci. Conserv. 1997, 1:217-238.
-
(1997)
Aquat. Sci. Conserv.
, vol.1
, pp. 217-238
-
-
Colorni, A.1
Burgess, P.2
-
8
-
-
78049431237
-
The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling
-
Flannery S., Bowie A.G. The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling. Biochem. Pharmacol. 2010, 80:1981-1991.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1981-1991
-
-
Flannery, S.1
Bowie, A.G.2
-
9
-
-
57649138445
-
The kinase activity of IL-1 receptor-associated kinase 4 is required for Interleukin-1 receptor/Toll-like receptor-induced TAK1-dependent NFκB activation
-
Fraczek J., Kim T.W., Xiao H., Yao J., Wen Q., Li Y., Casanova J.L., Pryjma J., Li X. The kinase activity of IL-1 receptor-associated kinase 4 is required for Interleukin-1 receptor/Toll-like receptor-induced TAK1-dependent NFκB activation. J. Biol. Chem. 2008, 283:31697-31705.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31697-31705
-
-
Fraczek, J.1
Kim, T.W.2
Xiao, H.3
Yao, J.4
Wen, Q.5
Li, Y.6
Casanova, J.L.7
Pryjma, J.8
Li, X.9
-
10
-
-
34249095729
-
Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling
-
Kawagoe T., Sato S., Jung A., Yamamoto M., Matsui K., Kato H., Uematsu S., Takeuchi O., Akira S. Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling. J. Exp. Med. 2007, 204:1013-1024.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1013-1024
-
-
Kawagoe, T.1
Sato, S.2
Jung, A.3
Yamamoto, M.4
Matsui, K.5
Kato, H.6
Uematsu, S.7
Takeuchi, O.8
Akira, S.9
-
11
-
-
34249078495
-
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity
-
Kim T.W., Staschke K., Bulek K., Yao J., Peters K., Oh K.H., Vandenburg Y., Xiao H., Qian W., Hamilton T., Min B., Sen G., Gilmour R., Li X. A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity. J. Exp. Med. 2007, 204:1025-1036.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1025-1036
-
-
Kim, T.W.1
Staschke, K.2
Bulek, K.3
Yao, J.4
Peters, K.5
Oh, K.H.6
Vandenburg, Y.7
Xiao, H.8
Qian, W.9
Hamilton, T.10
Min, B.11
Sen, G.12
Gilmour, R.13
Li, X.14
-
12
-
-
34250370957
-
IRAK-4 kinase activity is required for Interleukin-1 (IL-1) receptor- and Toll-like receptor 7-mediated signaling and gene expression
-
Koziczak-Holbro M., Joyce C., Glück A., Kinzel B., Müller M., Tschopp C., Mathison J.C., Davis C.N., Gram H. IRAK-4 kinase activity is required for Interleukin-1 (IL-1) receptor- and Toll-like receptor 7-mediated signaling and gene expression. J. Biol. Chem. 2007, 282:13552-13560.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13552-13560
-
-
Koziczak-Holbro, M.1
Joyce, C.2
Glück, A.3
Kinzel, B.4
Müller, M.5
Tschopp, C.6
Mathison, J.C.7
Davis, C.N.8
Gram, H.9
-
13
-
-
25444503240
-
Molecular structure of the TLR-associated kinase-4 death domain and its implications for TLR signaling
-
Lasker M.V., Gajjar M.M., Nair S.K. Molecular structure of the TLR-associated kinase-4 death domain and its implications for TLR signaling. J. Immunol. 2005, 175:4175-4179.
-
(2005)
J. Immunol.
, vol.175
, pp. 4175-4179
-
-
Lasker, M.V.1
Gajjar, M.M.2
Nair, S.K.3
-
14
-
-
43649094012
-
IRAK4 in TLR/IL-1R signaling: possible clinical applications
-
Li X. IRAK4 in TLR/IL-1R signaling: possible clinical applications. Eur. J. Immunol. 2008, 38:614-618.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 614-618
-
-
Li, X.1
-
15
-
-
0037117543
-
IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase
-
Li S., Strelow A., Fontana E.J., Wesche H. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc. Natl. Acad. Sci. USA 2002, 99:5567-5572.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5567-5572
-
-
Li, S.1
Strelow, A.2
Fontana, E.J.3
Wesche, H.4
-
16
-
-
79955991396
-
Orange-spotted grouper (Epinephelus coioides) TLR2, MyD88 and IL-1β involved in anti-Cryptocaryon irritans response
-
Li Y.W., Luo X.C., Dan X.M., Huang X.Z., Qiao W., Zhong Z.P., Li A.X. Orange-spotted grouper (Epinephelus coioides) TLR2, MyD88 and IL-1β involved in anti-Cryptocaryon irritans response. Fish Shellfish Immunol. 2011, 30:1230-1240.
-
(2011)
Fish Shellfish Immunol.
, vol.30
, pp. 1230-1240
-
-
Li, Y.W.1
Luo, X.C.2
Dan, X.M.3
Huang, X.Z.4
Qiao, W.5
Zhong, Z.P.6
Li, A.X.7
-
17
-
-
77953714711
-
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
-
Lin S.C., Lo Y.C., Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 2010, 465:885-890.
-
(2010)
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.C.1
Lo, Y.C.2
Wu, H.3
-
18
-
-
84866759390
-
Lipopolysaccharide-induced gene expression of interleukin-1 receptor-associated kinase 4 and interleukin-1β in roughskin sculpin (Trachidermus fasciatus)
-
Liu Y.Y., Yu S.S., Chai Y.M., Zhang Q.X., Yang H., Zhu Q. Lipopolysaccharide-induced gene expression of interleukin-1 receptor-associated kinase 4 and interleukin-1β in roughskin sculpin (Trachidermus fasciatus). Fish Shellfish Immunol. 2012, 33:690-698.
-
(2012)
Fish Shellfish Immunol.
, vol.33
, pp. 690-698
-
-
Liu, Y.Y.1
Yu, S.S.2
Chai, Y.M.3
Zhang, Q.X.4
Yang, H.5
Zhu, Q.6
-
20
-
-
69949161905
-
An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4
-
Motshwene P.G., Moncrieffe M.C., Grossmann J.G., Kao C., Ayaluru M., Sandercock A.M., Robinson C.V., Latz E., Gay N.J. An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4. J. Biol. Chem. 2009, 284:25404-25411.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25404-25411
-
-
Motshwene, P.G.1
Moncrieffe, M.C.2
Grossmann, J.G.3
Kao, C.4
Ayaluru, M.5
Sandercock, A.M.6
Robinson, C.V.7
Latz, E.8
Gay, N.J.9
-
21
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio M., Ni J., Feng P., Dixit V.M. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 1997, 278:1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
22
-
-
50849127162
-
Threonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation
-
Neumann D., Kollewe C., Pich A., Cao P., Resch K., Martin M.U. Threonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation. J. Leukocyte Biol. 2008, 84:807-813.
-
(2008)
J. Leukocyte Biol.
, vol.84
, pp. 807-813
-
-
Neumann, D.1
Kollewe, C.2
Pich, A.3
Cao, P.4
Resch, K.5
Martin, M.U.6
-
23
-
-
80455168991
-
Toll-like receptors in bony fish: from genomics to function
-
Palti Y. Toll-like receptors in bony fish: from genomics to function. Dev. Comp. Immunol. 2011, 35:1263-1272.
-
(2011)
Dev. Comp. Immunol.
, vol.35
, pp. 1263-1272
-
-
Palti, Y.1
-
24
-
-
17044410479
-
Functional characterization of full-length TLR3, IRAK-4, and TRAF6 in zebrafish (Danio rerio)
-
Phelan P.E., Mellon M.T., Kim C.H. Functional characterization of full-length TLR3, IRAK-4, and TRAF6 in zebrafish (Danio rerio). Mol. Immunol. 2005, 42:1057-1071.
-
(2005)
Mol. Immunol.
, vol.42
, pp. 1057-1071
-
-
Phelan, P.E.1
Mellon, M.T.2
Kim, C.H.3
-
25
-
-
0037471003
-
Pyogenic bacterial infections in humans with IRAK-4 deficiency
-
Picard C., Puel A., Bonnet M., Ku C.-L., Bustamante J., Yang K., Soudais C., Dupuis S., Feinberg J., Fieschi C., Elbim C., Hitchcock R., Lammas D., Davies G., Al-Ghonaium A., Al-Rayes H., Al-Jumaah S., Al-Hajjar S., Al-Mohsen I.Z., Frayha H.H., Rucker R., Hawn T.R., Aderem A., Tufenkeji H., Haraguchi S., Day N.K., Good R.A., Gougerot-Pocidalo M.A., Ozinsky A., Casanova J.-L. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003, 299:2076-2079.
-
(2003)
Science
, vol.299
, pp. 2076-2079
-
-
Picard, C.1
Puel, A.2
Bonnet, M.3
Ku, C.-L.4
Bustamante, J.5
Yang, K.6
Soudais, C.7
Dupuis, S.8
Feinberg, J.9
Fieschi, C.10
Elbim, C.11
Hitchcock, R.12
Lammas, D.13
Davies, G.14
Al-Ghonaium, A.15
Al-Rayes, H.16
Al-Jumaah, S.17
Al-Hajjar, S.18
Al-Mohsen, I.Z.19
Frayha, H.H.20
Rucker, R.21
Hawn, T.R.22
Aderem, A.23
Tufenkeji, H.24
Haraguchi, S.25
Day, N.K.26
Good, R.A.27
Gougerot-Pocidalo, M.A.28
Ozinsky, A.29
Casanova, J.-L.30
more..
-
26
-
-
2942748292
-
IRAK4 kinase activity is redundant for Interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness
-
Qin J., Jiang Z., Qian Y., Casanova J.L., Li X. IRAK4 kinase activity is redundant for Interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness. J. Biol. Chem. 2004, 279:26748-26753.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26748-26753
-
-
Qin, J.1
Jiang, Z.2
Qian, Y.3
Casanova, J.L.4
Li, X.5
-
27
-
-
33746365872
-
TLR8-mediated NF-κB and JNK activation are TAK1-independent and MEKK3-dependent
-
Qin J., Yao J., Cui G., Xiao H., Kim T.W., Fraczek J., Wightman P., Sato S., Akira S., Puel A., Casanova J.-L., Su B., Li X. TLR8-mediated NF-κB and JNK activation are TAK1-independent and MEKK3-dependent. J. Biol. Chem. 2006, 281:21013-21021.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 21013-21021
-
-
Qin, J.1
Yao, J.2
Cui, G.3
Xiao, H.4
Kim, T.W.5
Fraczek, J.6
Wightman, P.7
Sato, S.8
Akira, S.9
Puel, A.10
Casanova, J.-L.11
Su, B.12
Li, X.13
-
29
-
-
77957865629
-
Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation
-
Rebl A., Rebl H., Liu S., Goldammer T., Seyfert H.M. Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation. Dev. Comp. Immunol. 2011, 35:81-87.
-
(2011)
Dev. Comp. Immunol.
, vol.35
, pp. 81-87
-
-
Rebl, A.1
Rebl, H.2
Liu, S.3
Goldammer, T.4
Seyfert, H.M.5
-
30
-
-
0037020163
-
Identification of Threonine 66 as a functionally critical residue of the Interleukin-1 receptor-associated kinase
-
Ross K., Yang L., Dower S., Volpe F., Guesdon F. Identification of Threonine 66 as a functionally critical residue of the Interleukin-1 receptor-associated kinase. J. Biol. Chem. 2002, 277:37414-37421.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37414-37421
-
-
Ross, K.1
Yang, L.2
Dower, S.3
Volpe, F.4
Guesdon, F.5
-
31
-
-
62749099990
-
The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells
-
Song K.W., Talamas F.X., Suttmann R.T., Olson P.S., Barnett J.W., Lee S.W., Thompson K.D., Jin S., Hekmat-Nejad M., Cai T.Z., Manning A.M., Hill R.J., Wong B.R. The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells. Mol. Immunol. 2009, 46:1458-1466.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1458-1466
-
-
Song, K.W.1
Talamas, F.X.2
Suttmann, R.T.3
Olson, P.S.4
Barnett, J.W.5
Lee, S.W.6
Thompson, K.D.7
Jin, S.8
Hekmat-Nejad, M.9
Cai, T.Z.10
Manning, A.M.11
Hill, R.J.12
Wong, B.R.13
-
32
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki N., Suzuki S., Duncan G.S., Millar D.G., Wada T., Mirtsos C., Takada H., Wakeham A., Itie A., Li S., Penninger J.M., Wesche H., Ohashi P.S., Mak T.W., Yeh W.C. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature 2002, 416:750-756.
-
(2002)
Nature
, vol.416
, pp. 750-756
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
Millar, D.G.4
Wada, T.5
Mirtsos, C.6
Takada, H.7
Wakeham, A.8
Itie, A.9
Li, S.10
Penninger, J.M.11
Wesche, H.12
Ohashi, P.S.13
Mak, T.W.14
Yeh, W.C.15
-
33
-
-
77953238536
-
Evidence of molecular Toll-like receptor mechanisms in teleosts
-
Takano T., Hwang S.D., Kondo H., Hirono I., Aoki T., Sano M. Evidence of molecular Toll-like receptor mechanisms in teleosts. Fish Pathol. 2010, 45:1-16.
-
(2010)
Fish Pathol.
, vol.45
, pp. 1-16
-
-
Takano, T.1
Hwang, S.D.2
Kondo, H.3
Hirono, I.4
Aoki, T.5
Sano, M.6
-
34
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
35
-
-
84855725332
-
Innate and adaptive immunity in teleost fish: a review
-
Uribe C., Folch H., Enriquez R., Moran G. Innate and adaptive immunity in teleost fish: a review. Vet. Med. 2011, 56:486-503.
-
(2011)
Vet. Med.
, vol.56
, pp. 486-503
-
-
Uribe, C.1
Folch, H.2
Enriquez, R.3
Moran, G.4
-
36
-
-
33845231575
-
Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper
-
Wang Z., Liu J., Sudom A., Ayres M., Li S., Wesche H., Powers J.P., Walker N.P.C. Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper. Structure 2006, 14:1835-1844.
-
(2006)
Structure
, vol.14
, pp. 1835-1844
-
-
Wang, Z.1
Liu, J.2
Sudom, A.3
Ayres, M.4
Li, S.5
Wesche, H.6
Powers, J.P.7
Walker, N.P.C.8
-
37
-
-
0033516561
-
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
-
Wesche H., Gao X., Li X., Kirschning C.J., Stark G.R., Cao Z. IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J. Biol. Chem. 1999, 274:19403-19410.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19403-19410
-
-
Wesche, H.1
Gao, X.2
Li, X.3
Kirschning, C.J.4
Stark, G.R.5
Cao, Z.6
-
38
-
-
0034597766
-
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
-
Xu Y., Tao X., Shen B., Horng T., Medzhitov R., Manley J.L., Tong L. Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature 2000, 408:111-115.
-
(2000)
Nature
, vol.408
, pp. 111-115
-
-
Xu, Y.1
Tao, X.2
Shen, B.3
Horng, T.4
Medzhitov, R.5
Manley, J.L.6
Tong, L.7
-
39
-
-
84890817605
-
Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish
-
Yeh D.W., Liu Y.L., Lo Y.C., Yuh C.H., Yu G.Y., Lo J.F., Luo Y., Xiang R., Chuang T.H. Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish. Proc. Natl. Acad. Sci. USA 2013, 110:20711-20716.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20711-20716
-
-
Yeh, D.W.1
Liu, Y.L.2
Lo, Y.C.3
Yuh, C.H.4
Yu, G.Y.5
Lo, J.F.6
Luo, Y.7
Xiang, R.8
Chuang, T.H.9
-
40
-
-
84862806416
-
Identification and characterization of IL-1 receptor-associated kinase-4 (IRAK-4) in half-smooth tongue sole Cynoglossus semilaevis
-
Yu Y., Zhong Q., Li C., Jiang L., Wang Y., Sun Y., Wang X., Wang Z., Zhang Q. Identification and characterization of IL-1 receptor-associated kinase-4 (IRAK-4) in half-smooth tongue sole Cynoglossus semilaevis. Fish Shellfish Immunol. 2012, 32:609-615.
-
(2012)
Fish Shellfish Immunol.
, vol.32
, pp. 609-615
-
-
Yu, Y.1
Zhong, Q.2
Li, C.3
Jiang, L.4
Wang, Y.5
Sun, Y.6
Wang, X.7
Wang, Z.8
Zhang, Q.9
|