Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an african tree

Journal of Natural Products

Volumn 77, Issue 2, 2014, Pages 285-297

  Terada, Yuko ^a   Horie, Syunji ^b   Takayama, Hiromitsu ^c   Uchida, Kunitoshi ^d   Tominaga, Makoto ^d   Watanabe, Tatsuo ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b JOSAI INTERNATIONAL UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 HYDROXYPHENYL) 4 (3 NITROPHENYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 2 ONE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALKALOID; CALCIUM ION; CAPSAICIN; MENTHOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VOACANGINE;

ANIMAL TISSUE; ARTICLE; BARK; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STRAIN HEK293; COLD; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; HUMAN; HUMAN CELL; IC 50; MOLECULAR IMAGING; MOUSE; NONHUMAN; PLANT ROOT; RAT; SPINAL CORD NERVE CELL; SPINAL GANGLION; STIMULUS RESPONSE; TEMPERATURE SENSITIVITY; VOACANGA; VOACANGA AFRICANA;

AFRICA; ALKALOIDS; CALCIUM; CAPSAICIN; HUMANS; IBOGAINE; MENTHOL; MOLECULAR STRUCTURE; PLANT BARK; PYRIMIDINONES; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TREES; TRPV CATION CHANNELS; VOACANGA;

EID: 84896837091     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400885u     Document Type: Article

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