Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels

Molecular Pain

Volumn 5, Issue , 2009, Pages

  Malkia, Annika ^a   Pertusa, María ^a   Fernández Ballester, Gregorio ^a   Ferrer Montiel, Antonio ^a   Viana, Félix ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 (3 (4 METHOXYPHENYL)PROPOXY) 4 METHOXYPHENYLETHYL) 1H IMIDAZOLE; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; CAPSAICIN; CAPSAZEPINE; CLOTRIMAZOLE; DRUG DERIVATIVE; IMIDAZOLE DERIVATIVE; MENTHOL; MUTANT PROTEIN; N (4 TERT BUTYLPHENYL) 4 (3 CHLORO 2 PYRIDINYL) 1 PIPERAZINECARBOXAMIDE; N-(4-TERT-BUTYLPHENYL)-4-(3-CHLOROPYRIDIN-2-YL)TETRAHYDROPYRAZINE-1(2H)-CARBOXAMIDE; PYRAZINE DERIVATIVE; PYRIDINE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM8 PROTEIN, MOUSE; TYROSINE;

ANIMAL; ARTICLE; CHANNEL GATING; CHEMICAL STRUCTURE; CHEMISTRY; COLD; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MOUSE; MUTATION; PHENOTYPE; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CAPSAICIN; CLOTRIMAZOLE; COLD TEMPERATURE; HUMANS; IMIDAZOLES; ION CHANNEL GATING; MENTHOL; MICE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTANT PROTEINS; MUTATION; PHENOTYPE; PYRAZINES; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRPM CATION CHANNELS; TYROSINE;

EID: 75349111700     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-5-62     Document Type: Article

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