Inhibitory effect of Iboga-type indole alkaloids on capsaicin-induced contraction in isolated mouse rectum

Journal of Natural Medicines

Volumn 65, Issue 1, 2011, Pages 157-165

  Lo, Mee Wah ^a,b   Matsumoto, Kenjiro ^b   Iwai, Masumi ^a   Tashima, Kimihito ^b   Kitajima, Mariko ^a   Horie, Syunji ^b   Takayama, Hiromitsu ^a  

^a CHIBA UNIVERSITY   (Japan)

^b JOSAI INTERNATIONAL UNIVERSITY   (Japan)

Author keywords

Apocynaceae; Colon; Diarrhea; Iboga alkaloid; TRPV1; Voacangine

Indexed keywords

(7ALPHA)VOACANGINE HYDROXYINDOLENINE; 3 OXOVOACANGINE; ACETYLCHOLINE; ALKALOID; ANTIDIARRHEAL AGENT; CAPSAICIN; CORONARIDINE; IBOGA TYPE ALKALOID; ISOVOACANGINE; METHANOL; N (4 TERT BUTYLPHENYL) 4 (3 CHLORO 2 PYRIDINYL) 1 PIPERAZINECARBOXAMIDE; NICOTINE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; SUBSESSILINE; TETRAHYDROALSTONINE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VOACAMINE; VOACANGA AFRICANA EXTRACT; VOACANGINE; VOACRISTINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BARK; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; PLANT ROOT; PROTEIN LOCALIZATION; RECTUM; SMOOTH MUSCLE RELAXATION; TABERNAEMONTANA; TABERNAEMONTANA SUBGLOBOSA; VOACANGA; VOACANGA AFRICANA;

ANIMALS; APOCYNACEAE; CAPSAICIN; IMMUNOHISTOCHEMISTRY; INDOLE ALKALOIDS; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RECTUM; TRPV CATION CHANNELS;

EID: 78651405184     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-010-0478-6     Document Type: Article

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