Interaction between neuronal nitric-oxide synthase and tetrahydrobiopterin revisited: Studies on the nature and mechanism of tight pterin binding

Biochemistry

Volumn 53, Issue 8, 2014, Pages 1284-1295

  Heine, Christian L ^a   Kolesnik, Bernd ^a   Schmidt, Renate ^a   Werner, Ernst R ^b   Mayer, Bernd ^a   Gorren, Antonius C F ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROPERTIES; DISSOCIATION CONSTANT; EXPRESSION SYSTEM; KINETIC EXPERIMENT; NEURONAL NITRIC-OXIDE SYNTHASE (NNOS); NITRIC-OXIDE SYNTHASE; REDOX CHEMISTRY; TETRAHYDROBIOPTERIN;

BINDING ENERGY; BINDING SITES; COENZYMES; DISSOCIATION; ESCHERICHIA COLI; EXPERIMENTS;

DIMERS;

4 AMINO DIHYDROBIOPTERIN; 4 AMINO TETRAHYDROBIOPTERIN; DIHYDROBIOPTERIN; DIMER; NEURONAL NITRIC OXIDE SYNTHASE; PTERIDINE DERIVATIVE; PTERIN; RECOMBINANT ENZYME; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACULOVIRUS; BINDING AFFINITY; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; GEL ELECTROPHORESIS; INSECT CELL; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BINDING SITES; BIOPTERIN; ENZYME STABILITY; KINETICS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; OXYGEN; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RATS; SF9 CELLS; SPODOPTERA;

EID: 84896766944     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401307r     Document Type: Article

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