Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: Heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin

Biochemistry

Volumn 36, Issue 27, 1997, Pages 8422-8427

  Mayer, Bernd ^a   Wu, Chaoqun ^b   Gorren, Antonius C F ^a   Pfeiffer, Silvia ^a   Schmidt, Kurt ^a   Clark, Pamela ^b   Stuehr, Dennis J ^b   Werner, Ernst R ^c  

^a UNIVERSITY OF GRAZ   (Austria)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE SYNTHASE; PTERIN DERIVATIVE; TETRAHYDROBIOPTERIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; ENZYME ACTIVITY; GEL ELECTROPHORESIS; GEL FILTRATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY;

ANIMALS; BIOPTERIN; DIMERIZATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEME; KINETICS; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE; PTERIDINES; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY;

ESCHERICHIA COLI;

EID: 0030793667     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970144z     Document Type: Article

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