Oxygen-induced radical intermediates in the nNOS oxygenase domain regulated by L-arginine, tetrahydrobiopterin, and thiol

Biochemistry

Volumn 47, Issue 1, 2008, Pages 405-420

  Berka, Vladimír ^a   Wang, Lee Ho ^a   Tsai, Ah Lim ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; HYDROGEN PEROXIDE; NITRIC OXIDE; PARAMAGNETIC RESONANCE;

BIOPTERIN RADICALS; PEROXYNITRITE; SUPEROXIDES;

ENZYMES;

ARGININE; CITRULLINE; CYSTEINE; DITHIOTHREITOL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FERROUS ION; HYDROGEN PEROXIDE; NEURONAL NITRIC OXIDE SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITRIC OXIDE; OXYGEN; OXYGENASE; PEROXYNITRITE; RADICAL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TETRAHYDROBIOPTERIN; THIOL; WATER;

ARTICLE; CATALYSIS; DEGENERATIVE DISEASE; ELECTRON SPIN RESONANCE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT;

ANIMALS; ARGININE; BIOPTERIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; KINETICS; NITRIC OXIDE SYNTHASE TYPE I; OXIDATION-REDUCTION; OXYGEN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; REACTIVE OXYGEN SPECIES;

EID: 37849015171     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701677r     Document Type: Article

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